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Entry version 9 (12 Aug 2020)
Sequence version 1 (13 Feb 2019)
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Protein
Submitted name:

RNA polymerase II associated protein 1

Gene
N/A
Organism
Oryzias latipes (Japanese rice fish) (Japanese killifish)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
RNA polymerase II associated protein 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOryzias latipes (Japanese rice fish) (Japanese killifish)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataOvalentariaAtherinomorphaeBeloniformesAdrianichthyidaeOryziinaeOryzias
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000265180 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 22

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini230 – 270RPAP1_NInterPro annotationAdd BLAST41
Domaini360 – 425RPAP1_CInterPro annotationAdd BLAST66

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni19 – 100DisorderedSequence analysisAdd BLAST82
Regioni168 – 188DisorderedSequence analysisAdd BLAST21
Regioni268 – 297DisorderedSequence analysisAdd BLAST30

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi85 – 100PolyampholyteSequence analysisAdd BLAST16

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the RPAP1 family.ARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000007594

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024, ARM-type_fold
IPR013929, RNA_pol_II_AP1_C
IPR013930, RNA_pol_II_AP1_N
IPR039913, RPAP1/Rba50

The PANTHER Classification System

More...
PANTHERi
PTHR21483, PTHR21483, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08620, RPAP1_C, 1 hit
PF08621, RPAP1_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A3P9KNS2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLRRPQPSDC EADLLREQES FLASGAPSAA SVLRRPDKRR GQSGEAEGDG
60 70 80 90 100
SQENGGTQKD VVTIEDLPDE LPSLTPAPPK KSRFKASRVT FEEDDAEDRL
110 120 130 140 150
DTHDTHISAV LSRIVERDTS SVPISLPAFT GMAFPKVMHR SETSSQAPPS
160 170 180 190 200
SVRGMKSIFA RQIAAQKLNE AKTPQDHSSG SSQTSGLKEQ NLPAETGMDI
210 220 230 240 250
ALSDASVASQ PRLVSGQGLG VLDGSTETLR IHMENQAKLR VMSQSEILEE
260 270 280 290 300
QKKLLSQLDP RLVEFVRSQK AQSVQSEETN KKEDAREKAG GPPSSVPGFY
310 320 330 340 350
CERSMEEEEP QPPSAIITEV ELPVKPQKEW VHMDKLEPEK LEWMKDLPPP
360 370 380 390 400
RKKGTEKAMQ ARFDFAGTLM PPTEDLPTHL GLHHHGEEPE RAGYSLQELF
410 420 430 440 450
LLSRSQLIQQ RSLALNTLAN ILSKARAGEY ASALKGTVTS TLLDAGVLFL
460 470 480 490 500
LRFALDDGVE GVMSAAVHAL KALLVSSEDE ECMDSTFSWY LGLASFPLLP
510 520 530 540 550
SSQEDEEEED EGVDGCMKQT AKEKEEQKSD FDVTQQDVVK GLLKMKLLPR
560 570 580 590 600
LRYILEVMRP SPRVVQDVLQ ILTRVARHSL SSATEVLNCP RLMETVTSEF
610 620 630 640 650
LPTSWSASSS PNPQSIYGVP VASAMKLLRV LATSGRHNCA RLLNSLGVKE
660 670 680 690 700
RLSRLLGAEP SELLLEPSEA LRVTTEAYRF WAVAAGYGQA CQLYIDLYSA
710 720 730 740 750
LLKSLQSGHR LAPPSHSLQP LQLQRLSALL SLLTQVTHTA GCHQELQAGV
760 770 780 790 800
LSAQGEECPP PPPVSWGHVS GLQASLLGHL KGLVKNLDSP VQADSSLTLI
810 820 830 840 850
PAYLVYLQAY YQQLSRQVFF KPVETLQELE LLTSDVLLPL QCHSVVQGLM
860 870 880 890 900
NNLRSSSLVC NVQSHHPGPE TTSNLPGLAC AGWKERSGLV VPSSPFALVI
910 920 930 940 950
GLGALLETIT GIHRGLSSKF SSFLLSEPVI GYLQACSKST PTLSVSRAWL
960 970 980 990 1000
LRHEHLLLYL LLRMAHRLVP VDVEVAKQAS LYHQVALVLL PWLLPGSEYL
1010 1020 1030 1040 1050
AHELLSTVIF NKDFISEGHS GGPEAVELGE LKLHDDVRLH TTPSLQTVGA
1060 1070 1080 1090 1100
LLREACVQLP SIRGCFLTHL AYLEPSVIAS RKALLGRNPW ISSHLLPELT
1110 1120 1130 1140 1150
GPTLPSDWPF LPLIKLYEQT GVSGGGGLAV EELPAGALQA AVHCLQWLLL
1160 1170 1180 1190 1200
LEVWREESLK VVPPVAKLAR LSCVFLCSSD LFLERPVQKL TWGLFRLLTR
1210 1220 1230 1240 1250
ASRLDSLDLD VPPPGLASFQ DLYSALLAQY ESVSFGDQLF GCWVLLPLQR
1260 1270 1280 1290 1300
RYSASMRLAV FGEHVGMLRS LGVTLEQLSI PIERFTSPPE DSLPLLRLYF
1310 1320 1330 1340 1350
RSLVTGSLKL SWCPVLYVVA LSHVNSFIFS QDAAAQEVEA ARHSILRKIY
1360 1370 1380 1390 1400
YLTDEVLRNH LLLFRLPQPH TQLGFDTYAE LPPIRAKRLE SVCRAGTAKE

TA
Length:1,402
Mass (Da):154,204
Last modified:February 13, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD054E203C6FDFEAF
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSORLT00020016565; ENSORLP00020027785; ENSORLG00020010959
ENSORLT00020016651; ENSORLP00020010048; ENSORLG00020010959

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSORLT00020016565; ENSORLP00020027785; ENSORLG00020010959
ENSORLT00020016651; ENSORLP00020010048; ENSORLG00020010959

Phylogenomic databases

GeneTreeiENSGT00390000007594

Family and domain databases

InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR013929, RNA_pol_II_AP1_C
IPR013930, RNA_pol_II_AP1_N
IPR039913, RPAP1/Rba50
PANTHERiPTHR21483, PTHR21483, 1 hit
PfamiView protein in Pfam
PF08620, RPAP1_C, 1 hit
PF08621, RPAP1_N, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3P9KNS2_ORYLA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3P9KNS2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 13, 2019
Last sequence update: February 13, 2019
Last modified: August 12, 2020
This is version 9 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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