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Entry version 8 (11 Dec 2019)
Sequence version 1 (13 Feb 2019)
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Protein
Submitted name:

Cobaltochelatase subunit CobN

Gene

EFE42_02920

Organism
Methanohalophilus sp. RSK
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Cobaltochelatase subunit CobNImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:EFE42_02920Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMethanohalophilus sp. RSKImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri2485783 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiArchaeaEuryarchaeotaStenosarchaea groupMethanomicrobiaMethanosarcinalesMethanosarcinaceaeMethanohalophilusunclassified Methanohalophilus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000274413 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei1728 – 1750HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1643 – 1728DisorderedSequence analysisAdd BLAST86

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1645 – 1707PolarSequence analysisAdd BLAST63

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003672, CobN/Mg_chltase

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02514, CobN-Mg_chel, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A3M9LM43-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRFGKVCLLV LSVLIMLAVA MPAVSAAEQV NVTYIGLEDQ KGILNNASSG
60 70 80 90 100
NPYSDQINYT FVPAYDGWSV SDEIQNASTN GLNEFLLTQD VIFCDMLWEP
110 120 130 140 150
SWEPLNDTLY AAHLNGTSLL AIRSSSIPSY FDYKPDGTKE IWAEDKICTY
160 170 180 190 200
FNNMDSSSYS GRKSAENLLI HLSRDYGNHP EITDSWPVIN ITYIAYDSSN
210 220 230 240 250
PLSKASRTNP YAEFIDYTYI PSFNTSDWSP SDELMNASDS GFLSTQDVIF
260 270 280 290 300
CDMIMYDDFY NSTFYGPHEN GTSLLDVNSY GTPDFFDYVS NGSVNDHICN
310 320 330 340 350
YYNNMESSGN GLKSAENFLL HLSRNYGNHA EITDEWPQLN FTYVYYTHNE
360 370 380 390 400
PIEQASLTNP YAKFINFTYI PSYKSDWSGM SDELGNVSDS GFLSTQDAIF
410 420 430 440 450
CDMIGYDSEF NSTFLKAHDN GSSLLDINSA NAPAFFDYVS NGSENDTIAL
460 470 480 490 500
YYANMGESSS GRINAENLLI YSSREYGKMN FLTEGWQISG EGDVIPEAGL
510 520 530 540 550
YHPASEKRFF ETTEEYIQWY SNVSAGNHSY DPEKPTIGMW FHRSDITKEQ
560 570 580 590 600
LDVVNALIED IENKDCNVLV GFDTFNNITE YYCNENGTPL VQSVISLKSF
610 620 630 640 650
RLNYWNNEKG IEELKALNVP VLRGIVADVP SDPDPADANR GIPNSQMVYK
660 670 680 690 700
TIAPSVDGIF EYILIGNAVY DPDTESTQYI PLDSQIDWIS NRSIKWANLK
710 720 730 740 750
LKENKDKKVA VIYYNYPSGK DNIGASYLDT ITSMRLLLER MDSKNYTISN
760 770 780 790 800
IPENNSVLLE QLQSQGINAG SWAPGVMNEM VENRTEWGLQ LIPMETYHEW
810 820 830 840 850
FEQEVPENLQ NQVIEEWGAP WEEDLPENKS LMIWENETGK YLVIPAVQCG
860 870 880 890 900
DVWLMPQPAR GMMQNDDTLY HSALVPPPHQ YIGFYLWLNK EWNPDAIIHF
910 920 930 940 950
GTHGTHEWLP GQTYGLNRTE EWAPVLLQDL PNIYPYIVAN VGEGLTAEYR
960 970 980 990 1000
GNALIIDHLT PTLERSGSYG EIANLSQLMQ TYYGPEMSEQ TKQAYQVEII
1010 1020 1030 1040 1050
DEIVDLNLSV DLGLNVTELY DYNTSEFGDF IKNVLHEYVE EIEGENIPYG
1060 1070 1080 1090 1100
MHVLGEVPST NMTYPEKDEL SCMVRAMMGN KFEENVSAAF YPESEYPLGI
1110 1120 1130 1140 1150
PSNDTRVNLL VWEVVTNDTS VNDSQMLVYN ATNASVSSDL ERGIVYRDRL
1160 1170 1180 1190 1200
IGSAAEMDKM MSALSAGYIE PGPGTDPVMN PSAVPTGRNF YGVDPQLYPS
1210 1220 1230 1240 1250
EATWRLGKYL AEQMLTDYYD KHGEYPRKVS FSRFGVEFIR DHGTLEAEAL
1260 1270 1280 1290 1300
YLLGIKPGWD ANGRIDLSKF EVLPEEELQP SYGDYPGRPR IDIVYATAGM
1310 1320 1330 1340 1350
RDAFPGKIKM LDHAVAMADK APVGNYSNYV NESTSAIYDE LYAQFSKEMT
1360 1370 1380 1390 1400
EEEADELARQ LANMRCFAVM DGTYEIGTGN AIAASGSWDS EGEIAEIYLE
1410 1420 1430 1440 1450
KMGYVYGKDL WGFKCSELLT SNLRNVDASI HSDSSNLYDT LDNDDFFQYF
1460 1470 1480 1490 1500
GALNLATRYV SGTTPEMYVS DTRDPDAATM AGMQEYLMKN LRSRYWNPKW
1510 1520 1530 1540 1550
MDGMQESGYA GGRMMAEFVD NLWGWEVSNP ELVDDSVWQE TYELYVNEDM
1560 1570 1580 1590 1600
NEWFDANNAE AYQSISARML EAVRKGYWEP SNEVKETLVR EYVESVAENG
1610 1620 1630 1640 1650
PACCHHTCGN PLLDDYVDGI MSVPGADVVD QETMDKYKEQ LEAAIGSSEN
1660 1670 1680 1690 1700
PSDSESSSSS GGVGSAQIVN TTTTGTASNQ TTTTSDGGYG ESAQQPTSES
1710 1720 1730 1740 1750
AESSSDYVEG YEMTKENPRN KESGGSSFSG ADIVGTVLVL AGVGAMYVGF

RRRQL
Length:1,755
Mass (Da):196,959
Last modified:February 13, 2019 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCE83B28016C2EEEB
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
RDSK01000009 Genomic DNA Translation: RNI14356.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
RDSK01000009 Genomic DNA Translation: RNI14356.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR003672, CobN/Mg_chltase
PfamiView protein in Pfam
PF02514, CobN-Mg_chel, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3M9LM43_9EURY
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3M9LM43
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: February 13, 2019
Last sequence update: February 13, 2019
Last modified: December 11, 2019
This is version 8 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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