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Entry version 15 (10 Feb 2021)
Sequence version 1 (05 Dec 2018)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Seriola dumerili (Greater amberjack) (Caranx dumerili)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSeriola dumerili (Greater amberjack) (Caranx dumerili)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri41447 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiNeoteleosteiAcanthomorphataCarangariaCarangiformesCarangidaeSeriola
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000261420 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 306CENP-F_NInterPro annotationAdd BLAST306
Domaini1812 – 1953CENP-F_leu_zipInterPro annotationAdd BLAST142
Domaini2049 – 2192CENP-F_leu_zipInterPro annotationAdd BLAST144
Domaini2709 – 2751CENP-F_C_Rb_bdgInterPro annotationAdd BLAST43

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni123 – 159DisorderedSequence analysisAdd BLAST37
Regioni221 – 279DisorderedSequence analysisAdd BLAST59
Regioni442 – 523DisorderedSequence analysisAdd BLAST82
Regioni562 – 585DisorderedSequence analysisAdd BLAST24
Regioni1465 – 1487DisorderedSequence analysisAdd BLAST23
Regioni1519 – 1553DisorderedSequence analysisAdd BLAST35
Regioni1629 – 1694DisorderedSequence analysisAdd BLAST66
Regioni2622 – 2682DisorderedSequence analysisAdd BLAST61
Regioni2696 – 2718DisorderedSequence analysisAdd BLAST23
Regioni2757 – 2821DisorderedSequence analysisAdd BLAST65

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili20 – 68Sequence analysisAdd BLAST49
Coiled coili162 – 196Sequence analysisAdd BLAST35
Coiled coili279 – 437Sequence analysisAdd BLAST159
Coiled coili620 – 672Sequence analysisAdd BLAST53
Coiled coili687 – 714Sequence analysisAdd BLAST28
Coiled coili719 – 760Sequence analysisAdd BLAST42
Coiled coili782 – 813Sequence analysisAdd BLAST32
Coiled coili853 – 946Sequence analysisAdd BLAST94
Coiled coili1007 – 1077Sequence analysisAdd BLAST71
Coiled coili1095 – 1220Sequence analysisAdd BLAST126
Coiled coili1696 – 1723Sequence analysisAdd BLAST28
Coiled coili1731 – 1807Sequence analysisAdd BLAST77
Coiled coili1815 – 1884Sequence analysisAdd BLAST70
Coiled coili1927 – 1968Sequence analysisAdd BLAST42
Coiled coili1997 – 2017Sequence analysisAdd BLAST21
Coiled coili2025 – 2175Sequence analysisAdd BLAST151
Coiled coili2184 – 2309Sequence analysisAdd BLAST126
Coiled coili2324 – 2502Sequence analysisAdd BLAST179
Coiled coili2538 – 2593Sequence analysisAdd BLAST56

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi128 – 159PolarSequence analysisAdd BLAST32
Compositional biasi221 – 235PolarSequence analysisAdd BLAST15
Compositional biasi258 – 279PolarSequence analysisAdd BLAST22
Compositional biasi442 – 460PolyampholyteSequence analysisAdd BLAST19
Compositional biasi472 – 488PolyampholyteSequence analysisAdd BLAST17
Compositional biasi500 – 523PolyampholyteSequence analysisAdd BLAST24
Compositional biasi1465 – 1486PolyampholyteSequence analysisAdd BLAST22
Compositional biasi1629 – 1665PolyampholyteSequence analysisAdd BLAST37
Compositional biasi2622 – 2641PolarSequence analysisAdd BLAST20
Compositional biasi2775 – 2808PolarSequence analysisAdd BLAST34

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000111187

Identification of Orthologs from Complete Genome Data

More...
OMAi
YNAQLVQ

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR043513, Cenp-F
IPR018302, CenpF/LEK1_Rb-prot-bd
IPR019513, Centromere_CenpF_leu-rich_rpt
IPR018463, Centromere_CenpF_N

The PANTHER Classification System

More...
PANTHERi
PTHR18874, PTHR18874, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10490, CENP-F_C_Rb_bdg, 1 hit
PF10473, CENP-F_leu_zip, 2 hits
PF10481, CENP-F_N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A3B4T5Q2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSWAVEEWKD GLPGKALQKI QEMEVQLDKL KKERSQKQFQ LDSLEAALQK
60 70 80 90 100
QKQKVDSERT ETSALKRENQ CLVESCDSLE KTRQKVVHDL GVKEQQVSYL
110 120 130 140 150
EGQLNSCRKT IERLEQELKK YRNELDRSQP AGSCSLSSSS SEIQPYTTPQ
160 170 180 190 200
KSFSTPAPVP AYRQQDNRLE ELQEKYSQEV EERKKLETEL KVLQVKLLNQ
210 220 230 240 250
SSVSVSHKDI AARQAGSSIF PWQQQDQAHS RQSQDAMETP LKRRGASLWD
260 270 280 290 300
THEETPIKPN QRMSSSRAAQ SPSGSYQQME QLKTLNQELR GRVSELERNL
310 320 330 340 350
SNQEKEIRSQ AVKLQELQTQ LNQARKDLTE RDRDIAKTSH ELSQVTDRHQ
360 370 380 390 400
QAEAKCSSVE QKLKQVTEEM NCQRHNAESC KRTLEQKLKD QERDSQKELA
410 420 430 440 450
QLQSSHNALD QQLNQTRTKL TQEVQQSKKD YNVLQADMEK MGFQRRGMEK
460 470 480 490 500
EVEEQKQKLL RSEQSLQASQ TKEQDLRKKM EELQKEKNSV TVQLDQSSRR
510 520 530 540 550
LSQLEEEKKS ADQSLKRTQG QLDDLKAKSE GQLEELKKLQ LKLEQQTQAS
560 570 580 590 600
ARELDNLRKT LSDAETKNDR SQNELQKQKQ ETERVTNRFM DLEKESQELK
610 620 630 640 650
SNLTASQSEC KELKQEHQAL LEWKKEKETM INETEAVQKE LRDKMNNLES
660 670 680 690 700
SLSSLNETSD ELKKQLMSVE ADKASLSAHI DSLKGELLNK STELEEREHQ
710 720 730 740 750
YKELQSQLSE AGQKHTKELE NVGVQVAQLE AQVKNLELQL QKEITRAEQA
760 770 780 790 800
ERTNTQLLDE HQTACDLVRS KDQLVELGQA EISQLRESLS QTTAQQEEQN
810 820 830 840 850
ARLAEEKATL LKQCEESVSA KIEETEQIKL RFDESQQELL LTKNQVSSMQ
860 870 880 890 900
QFLKVQEQLG AELQKEIKTL SDNQEEHKKM YEKKSEELKL LEGELKDQQG
910 920 930 940 950
QTEEKEKQLR EAEAQILSLE KQKAELENVM QQMKKETEII QHVETEKINH
960 970 980 990 1000
LLEQISSLEE TVASNNDAAE KLPVLKNELD VVNQSHTDLK KSLEALEKSH
1010 1020 1030 1040 1050
SSTIQIKSNL ENTLTEKSNL VSALEKEVKE LTDKMSKELE SHASEIENFL
1060 1070 1080 1090 1100
NKEKNLKEQL QATKQSVTAA KAELSSRREE IRTMKTTLSA ASHGLEERDN
1110 1120 1130 1140 1150
TIKSLKEKLN KAEAEQAKTS DLLKEKMAAM NKIKVQLEML QMDLEDNETA
1160 1170 1180 1190 1200
MNTFDSQVEE LKGTIESLEA QLAQNETQMS HMEARLEDSK AQVSVLESRL
1210 1220 1230 1240 1250
EEVQSQNSVL ETQYVTAKEE LFDRSCEITR LEEDAVKGKQ LEESVAALES
1260 1270 1280 1290 1300
KLCQITEENI KLETALRQIT EDKDNDLNQF LQEKNIFETT LKQLTDNKEQ
1310 1320 1330 1340 1350
VENEIIQVKE QLEALEKLSE ENKQLQTTVE QLTEEKLQTD TKIDQMTAEK
1360 1370 1380 1390 1400
LDVESTVRQV TEEKAQLDHT LNLINEEKIQ LEAKLSELTS EKNDLVSNLN
1410 1420 1430 1440 1450
QVVEEKLQLE INYSQLTEEI IELQSSVNQV TEEKLQLQES TERHENEVAS
1460 1470 1480 1490 1500
LKGEKECIQR LLQASEQEHQ RTEEENRERS HQFEAEQAQL HQKLASLQKE
1510 1520 1530 1540 1550
LTVFRQQYES LLEQVGEQHS AIQQLSESQR TEGPGEEISH MESEETDIGV
1560 1570 1580 1590 1600
SPVEAEGQID VELTHDSSTK TESLPVKEQL SPVVSELGEL SHQSDEAFSE
1610 1620 1630 1640 1650
TELVFKEEVI DREMIQEHVE EERQACVVEE TRSNEEEKLH HQEQPSDQVP
1660 1670 1680 1690 1700
EDSSRPRDVL ENDPEVCEMS RPMSSLSETK ELKSPARDLS KGQDDLTHYK
1710 1720 1730 1740 1750
EMITKQENEL QTLRLEFDCL NSELALRKEL TSELEVQVTN LEKKVHAAEE
1760 1770 1780 1790 1800
EAHSAAHKLN ITLEEKTDLA DQLVRLSEER ETLTLQLQTA KCQLADVIEM
1810 1820 1830 1840 1850
LEGLEMAKGG CDEKFLQQES ELKRVRSEKA NLEQHILGME SELETMQVER
1860 1870 1880 1890 1900
ARLQDEMETK KRTCSGMEQQ IETLMAETSQ LRSELVSCTE ERDELNQSLG
1910 1920 1930 1940 1950
LWREKVHSLE KTNGDTRNLI SILEDDIRAG RKEYETLQGN MEKLKTERQQ
1960 1970 1980 1990 2000
LLEQINVQEQ AISQQSGERE ELIGHLNQIK EDHSSVNQST ESMVSKIQAL
2010 2020 2030 2040 2050
EGEVNRLSQS LESSLLEKGE IASRLNATQD EVQQMRTGIE KLQVRIESDE
2060 2070 2080 2090 2100
RKKKKMGELL KAAQRKSDLL QDRIDALERE KEDVEQSLEE AFLQAETAKA
2110 2120 2130 2140 2150
ELEEERRKVE EEKAKLSEKL LELSAMLESL RSEKQHMERE LETKHREIEE
2160 2170 2180 2190 2200
LKAAKEELER GLEKAEVDRR EEEERHKYKV EELEKGLREE AERQIREVDC
2210 2220 2230 2240 2250
LQEQLEASRQ REISLEQKSA ETEVEKDRVQ SLLVELEKEK QCLQSSLEEW
2260 2270 2280 2290 2300
QTEGDRLRSQ GDEWEKERNN LRARIEALEG EIKELKTLIK AKEEEKDVLE
2310 2320 2330 2340 2350
KEWEEEANQR QASVKSISSL MAEKERIEGE NGRMVEEKEK LQSTLLSVEQ
2360 2370 2380 2390 2400
ERNELRCTLA SVKEEKERLE QEREVVANEE KKLQTRLALI EEEKHDMQQT
2410 2420 2430 2440 2450
LSSLKQENKR IEEEKQKLEV EKQDLQSSLS LIESEKENLC SALSVLEKEK
2460 2470 2480 2490 2500
QRAEEEKEKL SESLQSTVAS MEKDLETHKL SVAQFNEQVS DLTSRAARLS
2510 2520 2530 2540 2550
KERDSALSKM NLWMKTCKQL EQEKQMMLNS SGNQKSTEAE KTKEMEELKA
2560 2570 2580 2590 2600
ALDGRKRELE EKDKELEEMK SELEEVNKLL EEKSTEADES MDKYCSLMVE
2610 2620 2630 2640 2650
VHKLEEANNA LTTRLEQITV SQRANEANTH SSSAVNAHLR RSGRKSSSKH
2660 2670 2680 2690 2700
QGEKMHENTE NMAPSTPQRS SPGKRGHRDI SDKDSAQEAL HNLTKKIKAN
2710 2720 2730 2740 2750
AATTPKPSTE QDDEFRPEGL PELVQKGFAD IPLGEMSPFI MRRTTVKRCS
2760 2770 2780 2790 2800
PRLAAKQTVL TSAPDGKLLG PTPLESPSAD SSNRKSLSPS SEEKPVCQSL
2810 2820
SLLKTPEQKD QTHQGDNCHV Q
Length:2,821
Mass (Da):324,765
Last modified:December 5, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF7A17CDF7D3F147D
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSSDUT00000001334; ENSSDUP00000001282; ENSSDUG00000001032

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSSDUT00000001334; ENSSDUP00000001282; ENSSDUG00000001032

Phylogenomic databases

GeneTreeiENSGT00730000111187
OMAiYNAQLVQ

Family and domain databases

InterProiView protein in InterPro
IPR043513, Cenp-F
IPR018302, CenpF/LEK1_Rb-prot-bd
IPR019513, Centromere_CenpF_leu-rich_rpt
IPR018463, Centromere_CenpF_N
PANTHERiPTHR18874, PTHR18874, 1 hit
PfamiView protein in Pfam
PF10490, CENP-F_C_Rb_bdg, 1 hit
PF10473, CENP-F_leu_zip, 2 hits
PF10481, CENP-F_N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3B4T5Q2_SERDU
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3B4T5Q2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 5, 2018
Last sequence update: December 5, 2018
Last modified: February 10, 2021
This is version 15 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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