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Entry version 14 (10 Feb 2021)
Sequence version 1 (05 Dec 2018)
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Protein

LAM_G_DOMAIN domain-containing protein

Gene
N/A
Organism
Paramormyrops kingsleyae
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
LAM_G_DOMAIN domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiParamormyrops kingsleyaeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1676925 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOsteoglossocephalaOsteoglossomorphaOsteoglossiformesMormyridaeParamormyrops
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000261540 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 23Sequence analysisAdd BLAST23
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501748648924 – 1280LAM_G_DOMAIN domain-containing proteinSequence analysisAdd BLAST1257

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini36 – 224LAM_G_DOMAINInterPro annotationAdd BLAST189

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni229 – 696DisorderedSequence analysisAdd BLAST468
Regioni718 – 749DisorderedSequence analysisAdd BLAST32
Regioni856 – 1007DisorderedSequence analysisAdd BLAST152

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi245 – 266PolyampholyteSequence analysisAdd BLAST22
Compositional biasi293 – 318PolarSequence analysisAdd BLAST26
Compositional biasi343 – 357Pro-richSequence analysisAdd BLAST15
Compositional biasi427 – 441Pro-richSequence analysisAdd BLAST15
Compositional biasi470 – 487Pro-richSequence analysisAdd BLAST18
Compositional biasi946 – 999Pro-richSequence analysisAdd BLAST54

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

CollagenARBA annotation, SignalSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000164061

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00247, Endostatin-like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.10.100.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016186, C-type_lectin-like/link_sf
IPR008160, Collagen
IPR010515, Collagenase_NC10/endostatin
IPR013320, ConA-like_dom_sf
IPR016187, CTDL_fold
IPR001791, Laminin_G

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01391, Collagen, 6 hits
PF06482, Endostatin, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00210, TSPN, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49899, SSF49899, 1 hit
SSF56436, SSF56436, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A3B3SBZ7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQSRLAQWSL GLCVVLCYCG LSAEVEVLEE ESSKAQLDLT ELIGVPLPPS
60 70 80 90 100
VSFITGYEGF PAYNFGPGAN IGRLTRMFVP DPFYRDFAIM ATVKPTTNHG
110 120 130 140 150
GVLFAITDAL QKVVHLGVAL SPVEDQTQRI ILYYSESGSS RSQEVASFKV
160 170 180 190 200
PDMSNKWNRF TLTMQEDEVR LYMDCEEYHR VAVQRSPWQL RFEASSGIFV
210 220 230 240 250
GNAGGTGLER FVGSIQQLVL KFDPRVADDQ CEEDDPYASG DGSGDDVTDS
260 270 280 290 300
REVPDELKKQ VEEREYAWSE NSQGAPVPAP PTEPYHDEDV TEYSGQPTPS
310 320 330 340 350
EEQTTVQPTP TAEPTTQRSS HTEEVEDRET FQTMSPGPKG EPGDPGVAGP
360 370 380 390 400
PGPRGPSGPS GEQEAQPGPR GPKGPPGPSG APGTPGKDGL PGIRGKDGKP
410 420 430 440 450
GEEGPQGFPG LPGEPGLKGE KGDPGVGLPG PPGPPGPPGL ASRPKFSGDV
460 470 480 490 500
EGYGSGFEDF DSDTEVIRGP PGLPGPPGPP GKPGPPGPRD DSASTGGLQT
510 520 530 540 550
GPLGPLGAAG EDGKPGEMGK PGAPGLDGAP GPEGQKGEKG DQGLTGPPGP
560 570 580 590 600
KGDSGEPGAT GLPGPMGAEG PAGFQGPPGP PGPPGRGFGL DLQDLEGSGI
610 620 630 640 650
LGMFEGAGPK GPPGLPGPPG LPGPKGKDGA DGVPGIGPKG SPGDPGQKGL
660 670 680 690 700
PGPAGSTGSP GVKGEKGDAG PKGEHGADGI SITGPPGPPG PPGSVINLQE
710 720 730 740 750
LLLNDTEGLF NFTEMLAPQG SQGLKGPKGD SGSAGIPGPA GPKGEKGEPG
760 770 780 790 800
LIITAEGSLI TGPLGPKGVK GERGLSGAVG IMGPIGPPGP KGEFGFPGRP
810 820 830 840 850
GRPGMIGIKG EKGETVGLPG PPGSPGPPGR PGFFNCPKGT VFQIPPRPHC
860 870 880 890 900
KTPINGNRES TPESGDGCQR TFVGTKGDKG EAGFPGQPGE TASWNPPISR
910 920 930 940 950
GENGDQGYKG EKGEKGEAGV TGPPGLPGKS GLVGPKGESV VGPQGPPGMP
960 970 980 990 1000
GLPGIPGYGR PGPQGPPGPP GPPGLPPRFG SAVAVPGPPG PPGPPGQPGS
1010 1020 1030 1040 1050
PSNGNSVVTY KNVESLFKHA HQAAEGTMVY ISDKSELYIR VREGWRKVQM
1060 1070 1080 1090 1100
GELISMPADS PSAAMPNGMG RPGEYSRPDV LSREPLGYLP GYNMLAHTIH
1110 1120 1130 1140 1150
TGPGLHLVAL NAPFSGDMGG TRGADFQCYQ QARAMGLEAT YRAFLSSHLQ
1160 1170 1180 1190 1200
DLITIVRKAN RHNVPVVNLK GETLFTNWMS IFSGNGGVFQ PDIPIYSFDG
1210 1220 1230 1240 1250
RNVMTDPSWP QKMLWHGSNM LGVRMTSSYC EAWRAGDMAV TGQASMLHGG
1260 1270 1280
LLLGQHSRSC SNRFVVLCVE NSYALDANGN
Length:1,280
Mass (Da):131,130
Last modified:December 5, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2594D7CC527A29CB
GO

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSPKIT00000008768; ENSPKIP00000027993; ENSPKIG00000009806

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSPKIT00000008768; ENSPKIP00000027993; ENSPKIG00000009806

Phylogenomic databases

GeneTreeiENSGT00940000164061

Family and domain databases

CDDicd00247, Endostatin-like, 1 hit
Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR016186, C-type_lectin-like/link_sf
IPR008160, Collagen
IPR010515, Collagenase_NC10/endostatin
IPR013320, ConA-like_dom_sf
IPR016187, CTDL_fold
IPR001791, Laminin_G
PfamiView protein in Pfam
PF01391, Collagen, 6 hits
PF06482, Endostatin, 2 hits
SMARTiView protein in SMART
SM00210, TSPN, 1 hit
SUPFAMiSSF49899, SSF49899, 1 hit
SSF56436, SSF56436, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3B3SBZ7_9TELE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3B3SBZ7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 5, 2018
Last sequence update: December 5, 2018
Last modified: February 10, 2021
This is version 14 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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