UniProtKB - A0A3B3IU26 (A0A3B3IU26_HUMAN)
Protein
Submitted name:
Tight junction protein ZO-2
Gene
TJP2
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Tight junction protein ZO-2Imported |
Gene namesi | Name:TJP2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:11828, TJP2 |
Subcellular locationi
Other locations
- bicellular tight junction Source: InterPro
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 10 – 97 | PDZInterPro annotationAdd BLAST | 88 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 129 – 156 | DisorderedSequence analysisAdd BLAST | 28 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 139 – 156 | PolyampholyteSequence analysisAdd BLAST | 18 |
Phylogenomic databases
GeneTreei | ENSGT00940000158634 |
Family and domain databases
Gene3Di | 2.30.42.10, 1 hit |
InterProi | View protein in InterPro IPR001478, PDZ IPR036034, PDZ_sf IPR005419, ZO-2 |
Pfami | View protein in Pfam PF00595, PDZ, 1 hit |
PRINTSi | PR01599, ZONOCCLUDNS2 |
SMARTi | View protein in SMART SM00228, PDZ, 1 hit |
SUPFAMi | SSF50156, SSF50156, 1 hit |
PROSITEi | View protein in PROSITE PS50106, PDZ, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 12 potential isoforms that are computationally mapped.Show allAlign All
A0A3B3IU26-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEELIWEQYT VTLQKDSKRG FGIAVSGGRD NPHFENGETS IVISDVLPGG
60 70 80 90 100
PADGLLQEND RVVMVNGTPM EDVLHSFAVQ QLRKSGKVAA IVVKRPRKVQ
110 120 130 140 150
VAALQASPPL DQDDRAFEVM DEFDGRSFRS GYSERSRLNS HGGRSRSWED
SPERGR
Computationally mapped potential isoform sequencesi
There are 12 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9UDY2 | ZO2_HUMAN | Tight junction protein ZO-2 | TJP2 X104, ZO2 | 1,190 | Annotation score: | ||
A0A1B0GTW1 | A0A1B0GTW1_HUMAN | Tight junction protein ZO-2 | TJP2 | 1,249 | Annotation score: | ||
A0A3B3IU51 | A0A3B3IU51_HUMAN | Tight junction protein ZO-2 | TJP2 | 1,047 | Annotation score: | ||
A0A3B3IRI3 | A0A3B3IRI3_HUMAN | Tight junction protein ZO-2 | TJP2 | 1,128 | Annotation score: | ||
A0A3B3IRV6 | A0A3B3IRV6_HUMAN | Tight junction protein ZO-2 | TJP2 | 851 | Annotation score: | ||
A0A3B3ISF1 | A0A3B3ISF1_HUMAN | Tight junction protein ZO-2 | TJP2 | 989 | Annotation score: | ||
A0A3B3ISZ5 | A0A3B3ISZ5_HUMAN | Tight junction protein ZO-2 | TJP2 | 1,099 | Annotation score: | ||
A0A3B3ITE1 | A0A3B3ITE1_HUMAN | Tight junction protein ZO-2 | TJP2 | 1,191 | Annotation score: | ||
A0A3B3IT83 | A0A3B3IT83_HUMAN | Tight junction protein ZO-2 | TJP2 | 621 | Annotation score: | ||
B1AN86 | B1AN86_HUMAN | Tight junction protein ZO-2 | TJP2 | 161 | Annotation score: | ||
There are more potential isoformsShow all |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 156 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL162730 Genomic DNA No translation available. AL358113 Genomic DNA No translation available. AL590238 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000649939; ENSP00000498043; ENSG00000119139 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL162730 Genomic DNA No translation available. AL358113 Genomic DNA No translation available. AL590238 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | A0A3B3IU26 |
Protocols and materials databases
Antibodypediai | 784, 387 antibodies |
Genome annotation databases
Ensembli | ENST00000649939; ENSP00000498043; ENSG00000119139 |
Organism-specific databases
HGNCi | HGNC:11828, TJP2 |
OpenTargetsi | ENSG00000119139 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000158634 |
Miscellaneous databases
ChiTaRSi | TJP2, human |
Gene expression databases
ExpressionAtlasi | A0A3B3IU26, baseline and differential |
Family and domain databases
Gene3Di | 2.30.42.10, 1 hit |
InterProi | View protein in InterPro IPR001478, PDZ IPR036034, PDZ_sf IPR005419, ZO-2 |
Pfami | View protein in Pfam PF00595, PDZ, 1 hit |
PRINTSi | PR01599, ZONOCCLUDNS2 |
SMARTi | View protein in SMART SM00228, PDZ, 1 hit |
SUPFAMi | SSF50156, SSF50156, 1 hit |
PROSITEi | View protein in PROSITE PS50106, PDZ, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A3B3IU26_HUMAN | |
Accessioni | A0A3B3IU26Primary (citable) accession number: A0A3B3IU26 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 5, 2018 |
Last sequence update: | December 5, 2018 | |
Last modified: | August 12, 2020 | |
This is version 10 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |