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Entry version 11 (07 Apr 2021)
Sequence version 1 (05 Dec 2018)
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Protein
Submitted name:

Laminin subunit alpha-3

Gene

LAMA3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.ARBA annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Laminin subunit alpha-3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LAMA3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 18

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:6483, LAMA3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Basement membraneARBA annotation, Extracellular matrix, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000053747

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi230 ↔ 242PROSITE-ProRule annotation
Disulfide bondi232 ↔ 249PROSITE-ProRule annotation
Disulfide bondi251 ↔ 260PROSITE-ProRule annotation
Disulfide bondi292 ↔ 301PROSITE-ProRule annotation
Disulfide bondi344 ↔ 353PROSITE-ProRule annotation
Disulfide bondi369 ↔ 381PROSITE-ProRule annotation
Disulfide bondi371 ↔ 388PROSITE-ProRule annotation
Disulfide bondi390 ↔ 399PROSITE-ProRule annotation
Disulfide bondi670 ↔ 679PROSITE-ProRule annotation
Disulfide bondi698 ↔ 710PROSITE-ProRule annotation
Disulfide bondi721 ↔ 730PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation, GlycoproteinARBA annotation

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
A0A3B3ITG1

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A3B3ITG1, baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini230 – 275Laminin EGF-likeInterPro annotationAdd BLAST46
Domaini276 – 319Laminin EGF-likeInterPro annotationAdd BLAST44
Domaini320 – 368Laminin EGF-likeInterPro annotationAdd BLAST49
Domaini369 – 419Laminin EGF-likeInterPro annotationAdd BLAST51
Domaini440 – 617Laminin IV type AInterPro annotationAdd BLAST178
Domaini651 – 697Laminin EGF-likeInterPro annotationAdd BLAST47
Domaini698 – 750Laminin EGF-likeInterPro annotationAdd BLAST53
Domaini1255 – 1456LAM_G_DOMAINInterPro annotationAdd BLAST202
Domaini1463 – 1625LAM_G_DOMAINInterPro annotationAdd BLAST163
Domaini1632 – 1792LAM_G_DOMAINInterPro annotationAdd BLAST161
Domaini1851 – 2015LAM_G_DOMAINInterPro annotationAdd BLAST165
Domaini2022 – 2195LAM_G_DOMAINInterPro annotationAdd BLAST174

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili817 – 900Sequence analysisAdd BLAST84
Coiled coili985 – 1026Sequence analysisAdd BLAST42
Coiled coili1062 – 1096Sequence analysisAdd BLAST35
Coiled coili1099 – 1133Sequence analysisAdd BLAST35
Coiled coili1187 – 1207Sequence analysisAdd BLAST21
Coiled coili1228 – 1248Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysisARBA annotation, Laminin EGF-like domainPROSITE-ProRule annotationARBA annotation, RepeatARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155638

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013320, ConA-like_dom_sf
IPR000742, EGF-like_dom
IPR009254, Laminin_aI
IPR010307, Laminin_dom_II
IPR002049, Laminin_EGF
IPR001791, Laminin_G
IPR000034, Laminin_IV

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00052, Laminin_B, 1 hit
PF00053, Laminin_EGF, 6 hits
PF00054, Laminin_G_1, 1 hit
PF02210, Laminin_G_2, 4 hits
PF06008, Laminin_I, 1 hit
PF06009, Laminin_II, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181, EGF, 4 hits
SM00180, EGF_Lam, 6 hits
SM00281, LamB, 1 hit
SM00282, LamG, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49899, SSF49899, 5 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS01248, EGF_LAM_1, 3 hits
PS50027, EGF_LAM_2, 6 hits
PS50025, LAM_G_DOMAIN, 5 hits
PS51115, LAMININ_IVA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Fragment.

This entry has 1 described isoform and 10 potential isoforms that are computationally mapped.Show allAlign All

A0A3B3ITG1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
IPIEEFSAEY VRPQVHCIAS YGRFVNQSAT CVSLAHETPP TALILDVLSG
60 70 80 90 100
RPFPHLPQQS SPSVDVLPGV TLKAPQNQVT LRGRVPHLGR YVFVIHFYQA
110 120 130 140 150
AHPTFPAQVS VDGGWPRAGS FHASFCPHVL GCRDQVIAEG QIEFDISEPE
160 170 180 190 200
VAATVKVPEG KSLVLVRVLV VPAENYDYQI LHKKSMDKSL EFITNCGKNS
210 220 230 240 250
FYLDPQTASR FCKNSARSLV AFYHKGALPC ECHPTGATGP HCSPEGGQCP
260 270 280 290 300
CQPNVIGRQC TRCATGHYGF PRCKPCSCGR RLCEEMTGQC RCPPRTVRPQ
310 320 330 340 350
CEVCETHSFS FHPMAGCEGC NCSRRGTIEA AMPECDRDSG QCRCKPRITG
360 370 380 390 400
RQCDRCASGF YRFPECVPCN CNRDGTEPGV CDPGTGACLC KENVEGTECN
410 420 430 440 450
VCREGSFHLD PANLKGCTSC FCFGVNNQCH SSHKRRTKFV DMLGWHLETA
460 470 480 490 500
DRVDIPVSFN PGSNSMVADL QELPATIHSA SWVAPTSYLG DKVSSYGGYL
510 520 530 540 550
TYQAKSFGLP GDMVLLEKKP DVQLTGQHMS IIYEETNTPR PDRLHHGRVH
560 570 580 590 600
VVEGNFRHAS SRAPVSREEL MTVLSRLADV RIQGLYFTET QRLTLSEVGL
610 620 630 640 650
EEASDTGSGR IALAVEICAC PPAYAGDSCQ GCSPGYYRDH KGLYTGRCVP
660 670 680 690 700
CNCNGHSNQC QDGSGICVNC QHNTAGEHCE RCQEGYYGNA VHGSCRACPC
710 720 730 740 750
PHTNSFATGC VVNGGDVRCS CKAGYTGTQC ERCAPGYFGN PQKFGGSCQP
760 770 780 790 800
CSCNSNGQLG SCHPLTGDCI NQEPKDSSPA EECDDCDSCV MTLLNDLATM
810 820 830 840 850
GEQLRLVKSQ LQGLSASAGL LEQMRHMETQ AKDLRNQLLN YRSAISNHGS
860 870 880 890 900
KIEGLERELT DLNQEFETLQ EKAQVNSRKA QTLNNNVNRA TQSAKELDVK
910 920 930 940 950
IKNVIRNVHI LLKQISGTDG EGNNVPSGDF SREWAEAQRM MRELRNRNFG
960 970 980 990 1000
KHLREAEADK RESQLLLNRI RTWQKTHQGE NNGLANSIRD SLNEYEAKLS
1010 1020 1030 1040 1050
DLRARLQEAA AQAKQANGLN QENERALGAI QRQVKEINSL QSDFTKYLTT
1060 1070 1080 1090 1100
ADSSLLQTNI ALQLMEKSQK EYEKLAASLN EARQELSDKV RELSRSAGKT
1110 1120 1130 1140 1150
SLVEEAEKHA RSLQELAKQL EEIKRNASGD ELVRCAVDAA TAYENILNAI
1160 1170 1180 1190 1200
KAAEDAANRA ASASESALQT VIKEDLPRKA KTLSSNSDKL LNEAKMTQKK
1210 1220 1230 1240 1250
LKQVNKLTNK LPDLWRKIES INQQLLPLGN ISDNMDRIRE LIQQARDAAS
1260 1270 1280 1290 1300
KVAVPMRFNG KSGVEVRLPN DLEDLKGYTS LSLFLQRPNS RENGGTENMF
1310 1320 1330 1340 1350
VMYLGNKDAS RDYIGMAVVD GQLTCVYNLG DREAELQVDQ ILTKSETKEA
1360 1370 1380 1390 1400
VMDRVKFQRI YQFARLNYTK GATSSKPETP GVYDMDGRNS NTLLNLDPEN
1410 1420 1430 1440 1450
VVFYVGGYPP DFKLPSRLSF PPYKGCIELD DLNENVLSLY NFKKTFNLNT
1460 1470 1480 1490 1500
TEVEPCRRRK EESDKNYFEG TGYARVPTQP HAPIPTFGQT IQTTVDRGLL
1510 1520 1530 1540 1550
FFAENGDRFI SLNIEDGKLM VRYKLNSELP KERGVGDAIN NGRDHSIQIK
1560 1570 1580 1590 1600
IGKLQKRMWI NVDVQNTIID GEVFDFSTYY LGGIPIAIRE RFNISTPAFR
1610 1620 1630 1640 1650
GCMKNLKKTS GVVRLNDTVG VTKKCSEDWK LVRSASFSRG GQLSFTDLGL
1660 1670 1680 1690 1700
PPTDHLQASF GFQTFQPSGI LLDHQTWTRN LQVTLEDGYI ELSTSDSGGP
1710 1720 1730 1740 1750
IFKSPQTYMD GLLHYVSVIS DNSGLRLLID DQLLRNSKRL KHISSSRQSL
1760 1770 1780 1790 1800
RLGGSNFEGC ISNVFVQRLS LSPEVLDLTS NSLKRDVSLG GCSLNKPPFL
1810 1820 1830 1840 1850
MLLKGSTRFN KTKTFRINQL LQDTPVASPR SVKVWQDACS PLPKTQANHG
1860 1870 1880 1890 1900
ALQFGDIPTS HLLFKLPQEL LKPRSQFAVD MQTTSSRGLV FHTGTKNSFM
1910 1920 1930 1940 1950
ALYLSKGRLV FALGTDGKKL RIKSKEKCND GKWHTVVFGH DGEKGRLVVD
1960 1970 1980 1990 2000
GLRAREGSLP GNSTISIRAP VYLGSPPSGK PKSLPTNSFV GCLKNFQLDS
2010 2020 2030 2040 2050
KPLYTPSSSF GVSSCLGGPL EKGIYFSEEG GHVVLAHSVL LGPEFKLVFS
2060 2070 2080 2090 2100
IRPRSLTGIL IHIGSQPGKH LCVYLEAGKV TASMDSGAGG TSTSVTPKQS
2110 2120 2130 2140 2150
LCDGQWHSVA VTIKQHILHL ELDTDSSYTA GQIPFPPAST QEPLHLGGAP
2160 2170 2180 2190
ANLTTLRIPV WKSFFGCLRN IHVNHIPVPV TEALEVQGPV SLNGCPDQ
Length:2,198
Mass (Da):242,172
Last modified:December 5, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i02F462D6DA5F5D83
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 10 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q16787LAMA3_HUMAN
Laminin subunit alpha-3
LAMA3 LAMNA
3,333Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MSA0A0A0A0MSA0_HUMAN
Laminin subunit alpha-3
LAMA3
3,277Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A0MTS5A0A0A0MTS5_HUMAN
HCG1811249, isoform CRA_f
LAMA3 hCG_1811249
1,668Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0A6YYF2A0A0A6YYF2_HUMAN
HCG1811249, isoform CRA_e
LAMA3 hCG_1811249
1,724Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EIP4K7EIP4_HUMAN
Laminin subunit alpha-3
LAMA3
1,147Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A075B783A0A075B783_HUMAN
Laminin subunit alpha-3
LAMA3
576Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7ERM0K7ERM0_HUMAN
Laminin subunit alpha-3
LAMA3
134Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EPP3K7EPP3_HUMAN
Laminin subunit alpha-3
LAMA3
94Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EMU9K7EMU9_HUMAN
Laminin subunit alpha-3
LAMA3
37Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
K7EQ42K7EQ42_HUMAN
Laminin subunit alpha-3
LAMA3
59Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section is used for sequence fragments to indicate that the residue at the extremity of the sequence is not the actual terminal residue in the complete protein sequence.<p><a href='/help/non_ter' target='_top'>More...</a></p>Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC010754 Genomic DNA No translation available.
AC067796 Genomic DNA No translation available.
AC090366 Genomic DNA No translation available.
KF456351 Genomic DNA No translation available.

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000649721; ENSP00000497885; ENSG00000053747

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC010754 Genomic DNA No translation available.
AC067796 Genomic DNA No translation available.
AC090366 Genomic DNA No translation available.
KF456351 Genomic DNA No translation available.

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PeptideAtlasiA0A3B3ITG1

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
1948, 192 antibodies

Genome annotation databases

EnsembliENST00000649721; ENSP00000497885; ENSG00000053747

Organism-specific databases

HGNCiHGNC:6483, LAMA3
OpenTargetsiENSG00000053747

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

GeneTreeiENSGT00940000155638

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
LAMA3, human

Gene expression databases

ExpressionAtlasiA0A3B3ITG1, baseline and differential

Family and domain databases

InterProiView protein in InterPro
IPR013320, ConA-like_dom_sf
IPR000742, EGF-like_dom
IPR009254, Laminin_aI
IPR010307, Laminin_dom_II
IPR002049, Laminin_EGF
IPR001791, Laminin_G
IPR000034, Laminin_IV
PfamiView protein in Pfam
PF00052, Laminin_B, 1 hit
PF00053, Laminin_EGF, 6 hits
PF00054, Laminin_G_1, 1 hit
PF02210, Laminin_G_2, 4 hits
PF06008, Laminin_I, 1 hit
PF06009, Laminin_II, 1 hit
SMARTiView protein in SMART
SM00181, EGF, 4 hits
SM00180, EGF_Lam, 6 hits
SM00281, LamB, 1 hit
SM00282, LamG, 5 hits
SUPFAMiSSF49899, SSF49899, 5 hits
PROSITEiView protein in PROSITE
PS01248, EGF_LAM_1, 3 hits
PS50027, EGF_LAM_2, 6 hits
PS50025, LAM_G_DOMAIN, 5 hits
PS51115, LAMININ_IVA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A3B3ITG1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A3B3ITG1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: December 5, 2018
Last sequence update: December 5, 2018
Last modified: April 7, 2021
This is version 11 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
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