UniProtKB - A0A3B3ISF6 (A0A3B3ISF6_HUMAN)
Protein
Submitted name:
Kelch domain-containing protein 7B
Gene
KLHDC7B
Organism
Homo sapiens (Human)
Status
Names & Taxonomyi
Protein namesi | Submitted name: Kelch domain-containing protein 7BImported |
Gene namesi | Name:KLHDC7BImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:25145, KLHDC7B |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 78 – 114 | DisorderedSequence analysisAdd BLAST | 37 | |
Regioni | 131 – 253 | DisorderedSequence analysisAdd BLAST | 123 | |
Regioni | 272 – 628 | DisorderedSequence analysisAdd BLAST | 357 | |
Regioni | 647 – 815 | DisorderedSequence analysisAdd BLAST | 169 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 228 – 250 | PolyampholyteSequence analysisAdd BLAST | 23 | |
Compositional biasi | 419 – 435 | Pro-richSequence analysisAdd BLAST | 17 | |
Compositional biasi | 483 – 506 | PolarSequence analysisAdd BLAST | 24 | |
Compositional biasi | 507 – 610 | Pro-richSequence analysisAdd BLAST | 104 | |
Compositional biasi | 667 – 691 | PolarSequence analysisAdd BLAST | 25 | |
Compositional biasi | 741 – 755 | Pro-richSequence analysisAdd BLAST | 15 |
Keywords - Domaini
Kelch repeatARBA annotation, RepeatARBA annotationPhylogenomic databases
GeneTreei | ENSGT00940000163480 |
Family and domain databases
Gene3Di | 2.120.10.80, 1 hit |
InterProi | View protein in InterPro IPR015915, Kelch-typ_b-propeller IPR006652, Kelch_1 |
Pfami | View protein in Pfam PF01344, Kelch_1, 2 hits |
SMARTi | View protein in SMART SM00612, Kelch, 3 hits |
SUPFAMi | SSF117281, SSF117281, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
A0A3B3ISF6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIQGTLEPDG PLWGWDWDSD NDWDSAVLAL LALAVVAATA LALHWFGSGH
60 70 80 90 100
DQEAAEPVST ALGAQPHQAG GAELALQPKS KVSDGSEGQS PGQGKPEPPG
110 120 130 140 150
RGQQSPVPAA APGGGLAAMA RLPLKTAVEE ARREALGQQR GSATPAAPRA
160 170 180 190 200
EGKEPPRPGT ALLGRSEAGG MSAPLLIHFT PRSPGSEAEA ETGGVRASSR
210 220 230 240 250
QAAGPAGQQD TGPWQAGAGP SGSMGRGRGR RRRMDAGSGD RARRPRKLDP
260 270 280 290 300
LRLGAAGSVW DAVDGAAALD AHARGLPTGP PLAQEPALPA LPAPRALQPG
310 320 330 340 350
SQTEGSGAKG GWSREASGVP APGGGWPWVS REVPGTRSFG PAPDSTRPWL
360 370 380 390 400
ESPPQGRPLS SQGPGATGAY DAGEAGADSS RDNSPAADLG PTRPPEQAKP
410 420 430 440 450
AAAGHSRAPS RSREPRPRSA SPPAAPGPGF PPEALTLPSP SDFLPLEVTQ
460 470 480 490 500
DPSVGENLRA APAPSSASAQ VLTSAPASVL APALASSPSS APTSATTSTS
510 520 530 540 550
SPTSAPAPAP TSAPTSTPAP APSPAAAATP APAPVPVPTL TPPSPALTPV
560 570 580 590 600
PTPALSPAPT PALTPAASPA LTPVPTPALS PAPTPAPTPA ASPAPAPTSA
610 620 630 640 650
PTPTPAASPA PADGSKPQES VALPRRYQEG QVSASWGNLI AMVLRSHPFP
660 670 680 690 700
RQDRPQGSVP RAVPGSPVGP STSTHSEDRH GPSSSVGTVI GTGTGGLVEA
710 720 730 740 750
GGQPQPRSSE TNGSPSPDPP PGLRGEGTRE KSLDPLPQAA MPRGPAQPPA
760 770 780 790 800
QRPPGPAASS SARRSQPVPQ LRKRSRCEIA PSSEQEVRPA ASGDPQGEAP
810 820 830 840 850
GEGGSPAGRS GALTEKQEEA RKLMVFLQRP GGWGVVEGPR KPSSRALEPA
860 870 880 890 900
TAAALRRRLD LGSCLDVLAF AQQHGEPGLA QETYALMSDN LLRVLGDPCL
910 920 930 940 950
YRRLSAADRE RILSLRTGRG RAVLGVLVLP SLYQGGRSGL PRGPRGEEPP
960 970 980 990 1000
AAAPVSLPLP AHLHVFNPRE NTWRPLTQVP EEAPLRGCGL CTMHNYLFLA
1010 1020 1030 1040 1050
GGIRGSGAKA VCSNEVFCYN PLTNIWSQVR PMQQARAQLK LVALDGLLYA
1060 1070 1080 1090 1100
IGGECLYSME CYDPRTDAWT PRAPLPAGTF PVAHEAVACR GDIYVTGGHL
1110 1120 1130 1140 1150
FYRLLRYSPV KDAWDECPYS ASHRRSSDIV ALGGFLYRFD LLRGVGAAVM
1160 1170 1180 1190 1200
RYNTVTGSWS RAASLPLPAP APLHCTTLGN TIYCLNPQVT ATFTVSGGTA
1210 1220 1230
QFQAKELQPF PLGSTGVLSP FILTLPPEDR LQTSL
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ96G42 | KLD7B_HUMAN | Kelch domain-containing protein 7B | KLHDC7B | 594 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U62317 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000648057; ENSP00000497256; ENSG00000130487 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U62317 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | A0A3B3ISF6 |
Protocols and materials databases
Antibodypediai | 237, 79 antibodies |
Genome annotation databases
Ensembli | ENST00000648057; ENSP00000497256; ENSG00000130487 |
Organism-specific databases
HGNCi | HGNC:25145, KLHDC7B |
OpenTargetsi | ENSG00000130487 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000163480 |
Miscellaneous databases
ChiTaRSi | KLHDC7B, human |
Gene expression databases
ExpressionAtlasi | A0A3B3ISF6, baseline and differential |
Family and domain databases
Gene3Di | 2.120.10.80, 1 hit |
InterProi | View protein in InterPro IPR015915, Kelch-typ_b-propeller IPR006652, Kelch_1 |
Pfami | View protein in Pfam PF01344, Kelch_1, 2 hits |
SMARTi | View protein in SMART SM00612, Kelch, 3 hits |
SUPFAMi | SSF117281, SSF117281, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A3B3ISF6_HUMAN | |
Accessioni | A0A3B3ISF6Primary (citable) accession number: A0A3B3ISF6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 5, 2018 |
Last sequence update: | December 5, 2018 | |
Last modified: | April 7, 2021 | |
This is version 10 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |