UniProtKB - A0A384NL63 (A0A384NL63_HUMAN)
Protein
Submitted name:
Epididymis secretory sperm binding protein
Gene
HNRPA3
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- mRNA binding Source: Ensembl
- RNA transmembrane transporter activity Source: Ensembl
GO - Biological processi
- mRNA transport Source: Ensembl
Keywordsi
Molecular function | RibonucleoproteinImportedARBA annotation, RNA-bindingPROSITE-ProRule annotationARBA annotation, Viral nucleoproteinImported |
Names & Taxonomyi
Protein namesi | Submitted name: Epididymis secretory sperm binding proteinImportedSubmitted name: Heterogeneous nuclear ribonucleoprotein A3, isoform CRA_bImported |
Gene namesi | Name:HNRPA3Imported ORF Names:hCG_2005824Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Other locations
- cytoplasm Source: Ensembl
- messenger ribonucleoprotein complex Source: Ensembl
- neuron projection Source: Ensembl
- ribonucleoprotein granule Source: Ensembl
Keywords - Cellular componenti
NucleusARBA annotation, VirionFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 35 – 118 | RRMInterPro annotationAdd BLAST | 84 | |
Domaini | 126 – 205 | RRMInterPro annotationAdd BLAST | 80 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 35 | DisorderedSequence analysisAdd BLAST | 35 | |
Regioni | 204 – 225 | DisorderedSequence analysisAdd BLAST | 22 | |
Regioni | 336 – 378 | DisorderedSequence analysisAdd BLAST | 43 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 11 – 34 | PolyampholyteSequence analysisAdd BLAST | 24 |
Keywords - Domaini
RepeatARBA annotationPhylogenomic databases
OMAi | SFTKHFE |
Family and domain databases
CDDi | cd12763, RRM1_hnRNPA3, 1 hit cd12582, RRM2_hnRNPA3, 1 hit |
Gene3Di | 3.30.70.330, 2 hits |
InterProi | View protein in InterPro IPR034513, hnRNPA3_RRM1 IPR034516, hnRNPA3_RRM2 IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom |
Pfami | View protein in Pfam PF00076, RRM_1, 2 hits |
SMARTi | View protein in SMART SM00360, RRM, 2 hits |
SUPFAMi | SSF54928, SSF54928, 2 hits |
PROSITEi | View protein in PROSITE PS50102, RRM, 2 hits |
i Sequence
Sequence statusi: Complete.
A0A384NL63-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEVKPPPGRP QPDSGRRRRR RGEEGHDPKE PEQLRKLFIG GLSFETTDDS
60 70 80 90 100
LREHFEKWGT LTDCVVMRDP QTKRSRGFGF VTYSCVEEVD AAMCARPHKV
110 120 130 140 150
DGRVVEPKRA VSREDSVKPG AHLTVKKIFV GGIKEDTEEY NLRDYFEKYG
160 170 180 190 200
KIETIEVMED RQSGKKRGFA FVTFDDHDTV DKIVVQKYHT INGHNCEVKK
210 220 230 240 250
ALSKQEMQSA GSQRGRGGGS GNFMGRGGNF GGGGGNFGRG GNFGGRGGYG
260 270 280 290 300
GGGGGSRGSY GGGDGGYNGF GGDGGNYGGG PGYSSRGGYG GGGPGYGNQG
310 320 330 340 350
GGYGGGGGYD GYNEGGNFGG GNYGGGGNYN DFGNYSGQQQ SNYGPMKGGS
360 370
FGGRSSGSPY GGGYGSGGGS GGYGSRRF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | GQ900946 mRNA Translation: ADO22463.1 CH471058 Genomic DNA Translation: EAX11064.1 |
RefSeqi | NP_001317178.1, NM_001330249.1 NP_919223.1, NM_194247.3 |
Genome annotation databases
GeneIDi | 220988 |
KEGGi | hsa:220988 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | GQ900946 mRNA Translation: ADO22463.1 CH471058 Genomic DNA Translation: EAX11064.1 |
RefSeqi | NP_001317178.1, NM_001330249.1 NP_919223.1, NM_194247.3 |
3D structure databases
SMRi | A0A384NL63 |
ModBasei | Search... |
Protocols and materials databases
Antibodypediai | 19537, 123 antibodies |
Genome annotation databases
GeneIDi | 220988 |
KEGGi | hsa:220988 |
Organism-specific databases
CTDi | 220988 |
Phylogenomic databases
OMAi | SFTKHFE |
Family and domain databases
CDDi | cd12763, RRM1_hnRNPA3, 1 hit cd12582, RRM2_hnRNPA3, 1 hit |
Gene3Di | 3.30.70.330, 2 hits |
InterProi | View protein in InterPro IPR034513, hnRNPA3_RRM1 IPR034516, hnRNPA3_RRM2 IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom |
Pfami | View protein in Pfam PF00076, RRM_1, 2 hits |
SMARTi | View protein in SMART SM00360, RRM, 2 hits |
SUPFAMi | SSF54928, SSF54928, 2 hits |
PROSITEi | View protein in PROSITE PS50102, RRM, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A384NL63_HUMAN | |
Accessioni | A0A384NL63Primary (citable) accession number: A0A384NL63 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 5, 2018 |
Last sequence update: | December 5, 2018 | |
Last modified: | December 2, 2020 | |
This is version 15 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |