Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 9 (17 Jun 2020)
Sequence version 1 (07 Nov 2018)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

AF4/FMR2 family member 3

Gene

AFF3

Organism
Balaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
AF4/FMR2 family member 3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:AFF3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBalaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri310752 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaWhippomorphaCetaceaMysticetiBalaenopteridaeBalaenoptera
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000261681 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 45DisorderedSequence analysisAdd BLAST45
Regioni104 – 127DisorderedSequence analysisAdd BLAST24
Regioni195 – 240DisorderedSequence analysisAdd BLAST46
Regioni270 – 375DisorderedSequence analysisAdd BLAST106
Regioni393 – 582DisorderedSequence analysisAdd BLAST190
Regioni601 – 762DisorderedSequence analysisAdd BLAST162
Regioni817 – 882DisorderedSequence analysisAdd BLAST66
Regioni907 – 996DisorderedSequence analysisAdd BLAST90
Regioni1134 – 1172DisorderedSequence analysisAdd BLAST39

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi195 – 222PolarSequence analysisAdd BLAST28
Compositional biasi288 – 305PolarSequence analysisAdd BLAST18
Compositional biasi323 – 340PolarSequence analysisAdd BLAST18
Compositional biasi408 – 424PolarSequence analysisAdd BLAST17
Compositional biasi430 – 444PolarSequence analysisAdd BLAST15
Compositional biasi475 – 526PolarSequence analysisAdd BLAST52
Compositional biasi671 – 702PolyampholyteSequence analysisAdd BLAST32
Compositional biasi703 – 717PolarSequence analysisAdd BLAST15
Compositional biasi845 – 874PolyampholyteSequence analysisAdd BLAST30
Compositional biasi907 – 921PolarSequence analysisAdd BLAST15
Compositional biasi930 – 990PolarSequence analysisAdd BLAST61
Compositional biasi1134 – 1152PolarSequence analysisAdd BLAST19

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR007797 TF_AF4/FMR2

The PANTHER Classification System

More...
PANTHERi
PTHR10528 PTHR10528, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05110 AF-4, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A384BCQ1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MLSGSGRAEK PEERQSRSLA SCARFPLPSS GEGGRSSSSV IPVSADGVEG
60 70 80 90 100
TAWHRHRGGP MRGGQGEDIL NQRSDSLVVE FQSSASRCRR YYIGVYEPDR
110 120 130 140 150
NVLRRKERER RNQETQQDDG AFNSSYSLFS EPYKTNKGDE LSNRLQNTLG
160 170 180 190 200
NYDEMKDFLT DRSNQSHLVG VPKPGVPQAP VNKIDEHFVA DSRAQTQPAS
210 220 230 240 250
VCSTTSSTPA VVPGQQSKRG TVGWQKAGHP PSDGQQRATQ QGSLRTLLGD
260 270 280 290 300
GVGRQQPRTK QVCNVEVGLQ TQDRPPAMGA KHSGSGHCVQ NFPPSLASKP
310 320 330 340 350
SLVQQKPTAY VRPMDGQDQA PDESPKLKSS TETSVHCASY RGASGTKPES
360 370 380 390 400
ARAKAKLSKF SIPKQGEESR SGETNSCVEE IIREMTWLPP LSAIPAPGKV
410 420 430 440 450
EPSKFPFPNK DSQLTSSGHS NPKKGDAETG SPDNGTSTTS MLEDDLKLSS
460 470 480 490 500
DEEENEQQAA QRTALHALSD SAGLPQANCR PSVPSSKGSS SGSSSSGSSS
510 520 530 540 550
SSDSESSSGS DSESESSSSE SEGSKPPHYS SPEAEPASSN KWQLDKWLNK
560 570 580 590 600
VNPHKPPILI QNESHGPESN QYYTPVKDEA PDCGKLPDNV CPTSLRDKDI
610 620 630 640 650
KSACKEEQRP RTANKAPGSK GVKQKSPPAA VAVAVTTANA PPPTEPAGAD
660 670 680 690 700
ALGASVGIPP EPPKPRPCGN SRTSHRKELR SAVTCEKRRT RGLSRIVPKS
710 720 730 740 750
KEFIETESSS SSSSSDSDLE SEQEDFPLSK ATAASGSDPR LKEAANSISG
760 770 780 790 800
GGPRAPVGSI NARTTSDIAK ELEEQFYTLV PFGRNELLSP LKDSDEVRSL
810 820 830 840 850
WVKIDLTLLS RIPEHLPQEP GVLSAPAAKD TESAPPSHAS DAPAEKALPK
860 870 880 890 900
SKRKRKCDNE EDYREIKKAQ GEKESSSRLT ASANSTLSAN HCNVNVNSLA
910 920 930 940 950
IPINKNEKML RSPTSPLSDA SKHKYSGEDL TSPSRSNSNG LFTSASSNKK
960 970 980 990 1000
HKAENQLQTH GGDLTKAAHN NSENNVLHKS RPQTEPWSPG SNGHRDCKRQ
1010 1020 1030 1040 1050
KLIFDDMPRS ADYFMQEAKR MKHKADAMVE KFGKALNYAE AALSFIECGN
1060 1070 1080 1090 1100
AMEQGPMESK SPYTMYSETV ELIRYAMRLK THSGPNATPE DKQLAALCYR
1110 1120 1130 1140 1150
CLALLYWRMF RLKRDHAVKY SKALIDYFKN SSKAAQAPSP WGASGKSTGT
1160 1170 1180 1190 1200
PSPMSPNPSP TSSVGSQGSL SNGNALSPST IVSIPQRIHQ MAANHVSITN
1210 1220 1230 1240 1250
SILHSYDYWE MADNLAKENR EFFNDLDLLM GPVTLHSSME HLVQYSQQGL
1260
YWLRNSTHLT
Length:1,260
Mass (Da):136,467
Last modified:November 7, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD1AE6C791DE11D2E
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_007197471.1, XM_007197409.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
103013811

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
bacu:103013811

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_007197471.1, XM_007197409.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

GeneIDi103013811
KEGGibacu:103013811

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
3899

Family and domain databases

InterProiView protein in InterPro
IPR007797 TF_AF4/FMR2
PANTHERiPTHR10528 PTHR10528, 1 hit
PfamiView protein in Pfam
PF05110 AF-4, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A384BCQ1_BALAS
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A384BCQ1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 7, 2018
Last sequence update: November 7, 2018
Last modified: June 17, 2020
This is version 9 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again