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Entry version 4 (13 Feb 2019)
Sequence version 1 (07 Nov 2018)
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Protein
Submitted name:

CDK5 regulatory subunit-associated protein 2 isoform X3

Gene

CDK5RAP2

Organism
Balaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
CDK5 regulatory subunit-associated protein 2 isoform X3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CDK5RAP2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBalaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri310752 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaCetaceaMysticetiBalaenopteridaeBalaenoptera
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000261681 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini60 – 130Cnn_1NInterPro annotationAdd BLAST71

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili60 – 80Sequence analysisAdd BLAST21
Coiled coili103 – 130Sequence analysisAdd BLAST28
Coiled coili139 – 177Sequence analysisAdd BLAST39
Coiled coili216 – 243Sequence analysisAdd BLAST28
Coiled coili271 – 312Sequence analysisAdd BLAST42
Coiled coili320 – 354Sequence analysisAdd BLAST35
Coiled coili394 – 428Sequence analysisAdd BLAST35
Coiled coili436 – 485Sequence analysisAdd BLAST50
Coiled coili575 – 619Sequence analysisAdd BLAST45
Coiled coili1212 – 1232Sequence analysisAdd BLAST21
Coiled coili1294 – 1314Sequence analysisAdd BLAST21
Coiled coili1400 – 1441Sequence analysisAdd BLAST42
Coiled coili1443 – 1491Sequence analysisAdd BLAST49
Coiled coili1561 – 1588Sequence analysisAdd BLAST28

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012943 Cnn_1N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07989 Cnn_1N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

A0A383ZSX5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMDSVLEEDV TLPGIRSGCS GLVPNLPDDL DGISPIAGLG NGVLPRVSEE
60 70 80 90 100
TVSPTRARNM KDFENQITEL KKENFNLKLR IYFLEERMQQ EFDGPTEHVY
110 120 130 140 150
KTNIELKVEV ESLKRELQER ERLLVKASKA VESLAEGGGS EMQRVKQEAQ
160 170 180 190 200
KKVRQVEELL TRRMLLLEED VKAAQAELEK AFAGTETEKA LRLSLENKLS
210 220 230 240 250
EMKKMHEGDL EMALVLEEKD RLIEELKLSL KSKEALIQCL KEEKSQMASP
260 270 280 290 300
DENVSSGELR GLPAAVRGDE ERETEAAQME QEKERNRFEE RIQALQKDLR
310 320 330 340 350
EKEREIATEK KNSLKRDKAI QGLTMALKSK EKEIEELNSE IEELNAAFAK
360 370 380 390 400
AREAPQKAQT QKFQGSEDYE AALLEKAALL AELRSENLTK STENHRLRRS
410 420 430 440 450
IKRVTRELSD LQQERERLEK ELGAAHRERS KGDRITHDLR NEVEKLRNEV
460 470 480 490 500
NEREKAVENR YKSLLNESNK KLHSQEQVIR SLTESASQKD LLLQKFNEKE
510 520 530 540 550
LDAIQQNRYL MTAEDLEFRS ENLITEKCSS QSPGSKSIFS EEKQPLGYEE
560 570 580 590 600
LIQVLKKEQD IYTHLVKSLQ DSDSVNNLQA ELNSIFALRK RLERDVLSYQ
610 620 630 640 650
NLQKALEEQI SEIRRREEEP FSFYSDQTSY LSICLEEHNR FQVEHFSQEE
660 670 680 690 700
LKEKVGDLIQ LVKELYADNQ HLKKTIFDLS SMGFPGEDRP ESVDQMELLA
710 720 730 740 750
SKEDEDSSRI GEDDKNHLLS GECLEQRNKT MEDNSKGGCK NGYLRHTDSS
760 770 780 790 800
ILDSDGAHRS GCPGDQSLEE GELLSLLAPL FSEKALWLLE SRPDLQKVLR
810 820 830 840 850
ELLLEQMCLR EQEASGEHPD GKTEKTLGQM AVQLRGELGH FIQANLSSKP
860 870 880 890 900
RDELKWPPGA QLAKAAEASE VEQKDASTQT MAVEGDTVRF RHEGTREPWG
910 920 930 940 950
EQPTDAVSSA ERQPESSRRM PGRQAAALSF PRGTEKDVKK SRLPILIKPS
960 970 980 990 1000
RSLGSVCRLP APQEVVAQQQ GELKEFKIRN KQRHQKLILA EAVMEGRPAP
1010 1020 1030 1040 1050
DKALLKAQPL VGAAYRDSPG EREGPQATPC VWRDKERDED QQASCETDSE
1060 1070 1080 1090 1100
IYQPDDLAIF PPCEEHPSED FPGPTSVATY LSPKSQFSAK VSVVETNQLE
1110 1120 1130 1140 1150
NSDTSNDKET LKRKICDLET ELEVYRNFIL QLQKHSQFSE AIVTVLCGRE
1160 1170 1180 1190 1200
GAQDGLNKSK GSTDEEEVTF SRLHQVRYVK HMKLLHLLAP EMIDGRALES
1210 1220 1230 1240 1250
LRLQLVDREY ELQKEQNLNL ELFGEIHNLQ NKFRDLSPSR YDSLVQAQAR
1260 1270 1280 1290 1300
ELSLQRQQIK DSHGICVVYR RHMNTMIKAF EELLQASDVD CRVAEGFQEQ
1310 1320 1330 1340 1350
LNQCAELLKQ LEKLFLKGNS VEVAMNTQEE LRERIEEDNL SYQHILPESP
1360 1370 1380 1390 1400
APSASRALSD CHVLSDCEMS EKSSFSREQK QDSETEKTSV LANNVSHDLL
1410 1420 1430 1440 1450
MEHIQEIRSL RKRLEESIKT NEKLRRQLER QGSEVDQDQQ KENEKLRASL
1460 1470 1480 1490 1500
SRKTAGLEHL RREFACVRAE NDRLQRAVGE KESENQRLLR EVCHGRSELS
1510 1520 1530 1540 1550
RVQEEVKVRQ QLLAQNDQLL QSLRVELKVY EKLDEEHRRP RETRAEASGE
1560 1570 1580 1590 1600
GWRGQDPSGH LHGLLTEIQA LRAQLERSIE TNSALQSRRE EQLVQGGEEA
1610 1620 1630 1640 1650
QEADLTLALQ TLSVPERPLQ LDKPDGDKCP VAADNSYDLF DSTPAVPPRS
1660 1670 1680 1690 1700
ASETPPLSAN DMDTLSCDSG GSITSASDMS RLVPGHRLWA STSGCHVLGL
1710 1720 1730 1740 1750
TEDYDALCEQ VGRGQKLLAE MDMRIQEAPS PTSQELATKR PHAAPRSSFV
1760 1770 1780 1790 1800
AGVGAARLSL DEASRLLTLL WRVSLPTSGQ GALRCEQTGE LKAEISKLHK
1810 1820 1830 1840 1850
KLFEQEKKLQ NTMKLLQLSK NQEKVIFDQL VVTHKVLRKA RGNLEARECP
1860
SWNVQSQQAR LLRRTFSQ
Length:1,868
Mass (Da):212,543
Last modified:November 7, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7BAAABC1565E8397
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A383ZTD5A0A383ZTD5_BALAS
CDK5 regulatory subunit-associated ...
CDK5RAP2
1,898Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A383ZSS7A0A383ZSS7_BALAS
CDK5 regulatory subunit-associated ...
CDK5RAP2
1,834Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A383ZSV6A0A383ZSV6_BALAS
CDK5 regulatory subunit-associated ...
CDK5RAP2
1,902Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A383ZSV2A0A383ZSV2_BALAS
CDK5 regulatory subunit-associated ...
CDK5RAP2
1,875Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A383ZSU7A0A383ZSU7_BALAS
CDK5 regulatory subunit-associated ...
CDK5RAP2
1,907Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A383ZSY1A0A383ZSY1_BALAS
CDK5 regulatory subunit-associated ...
CDK5RAP2
1,870Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A383ZTE0A0A383ZTE0_BALAS
CDK5 regulatory subunit-associated ...
CDK5RAP2
1,661Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_007178186.1, XM_007178124.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
103013900

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_007178186.1, XM_007178124.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi103013900

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55755

Family and domain databases

InterProiView protein in InterPro
IPR012943 Cnn_1N
PfamiView protein in Pfam
PF07989 Cnn_1N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A383ZSX5_BALAS
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A383ZSX5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 7, 2018
Last sequence update: November 7, 2018
Last modified: February 13, 2019
This is version 4 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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