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Entry version 4 (13 Feb 2019)
Sequence version 1 (07 Nov 2018)
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Protein
Submitted name:

CDK5 regulatory subunit-associated protein 2 isoform X4

Gene

CDK5RAP2

Organism
Balaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
CDK5 regulatory subunit-associated protein 2 isoform X4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:CDK5RAP2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiBalaenoptera acutorostrata scammoni (North Pacific minke whale) (Balaenoptera davidsoni)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri310752 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCetartiodactylaCetaceaMysticetiBalaenopteridaeBalaenoptera
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000261681 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini60 – 130Cnn_1NInterPro annotationAdd BLAST71

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili60 – 80Sequence analysisAdd BLAST21
Coiled coili103 – 130Sequence analysisAdd BLAST28
Coiled coili139 – 177Sequence analysisAdd BLAST39
Coiled coili216 – 243Sequence analysisAdd BLAST28
Coiled coili271 – 312Sequence analysisAdd BLAST42
Coiled coili320 – 354Sequence analysisAdd BLAST35
Coiled coili356 – 412Sequence analysisAdd BLAST57
Coiled coili502 – 546Sequence analysisAdd BLAST45
Coiled coili1139 – 1159Sequence analysisAdd BLAST21
Coiled coili1221 – 1241Sequence analysisAdd BLAST21
Coiled coili1327 – 1361Sequence analysisAdd BLAST35
Coiled coili1409 – 1457Sequence analysisAdd BLAST49
Coiled coili1527 – 1554Sequence analysisAdd BLAST28

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012943 Cnn_1N

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07989 Cnn_1N, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 7 potential isoforms that are computationally mapped.Show allAlign All

A0A383ZSS7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMDSVLEEDV TLPGIRSGCS GLVPNLPDDL DGISPIAGLG NGVLPRVSEE
60 70 80 90 100
TVSPTRARNM KDFENQITEL KKENFNLKLR IYFLEERMQQ EFDGPTEHVY
110 120 130 140 150
KTNIELKVEV ESLKRELQER ERLLVKASKA VESLAEGGGS EMQRVKQEAQ
160 170 180 190 200
KKVRQVEELL TRRMLLLEED VKAAQAELEK AFAGTETEKA LRLSLENKLS
210 220 230 240 250
EMKKMHEGDL EMALVLEEKD RLIEELKLSL KSKEALIQCL KEEKSQMASP
260 270 280 290 300
DENVSSGELR GLPAAVRGDE ERETEAAQME QEKERNRFEE RIQALQKDLR
310 320 330 340 350
EKEREIATEK KNSLKRDKAI QGLTMALKSK EKEIEELNSE IEELNAAFAK
360 370 380 390 400
AREAPQKAQT QKFQDLRNEV EKLRNEVNER EKAVENRYKS LLNESNKKLH
410 420 430 440 450
SQEQVIRSLT ESASQKDLLL QKFNEKELDA IQQNRYLMTA EDLEFRSENL
460 470 480 490 500
ITEKCSSQSP GSKSIFSEEK QPLGYEELIQ VLKKEQDIYT HLVKSLQDSD
510 520 530 540 550
SVNNLQAELN SIFALRKRLE RDVLSYQNLQ KALEEQISEI RRREEEPFSF
560 570 580 590 600
YSDQTSYLSI CLEEHNRFQV EHFSQEELKE KVGDLIQLVK ELYADNQHLK
610 620 630 640 650
KTIFDLSSMG FPGEDRPESV DQMELLASKE DEDSSRIGED DKNHLLSGEC
660 670 680 690 700
LEQRNKTMED NSKGGCKNGY LRHTDSSILD SDGAHRSGCP GDQSLEEGEL
710 720 730 740 750
LSLLAPLFSE KALWLLESRP DLQKVLRELL LEQMCLREQE ASGEHPDGKT
760 770 780 790 800
EKTLGQMAVQ LRGELGHFIQ ANLSSKPRDE LKWPPGAQLA KAAEASEVEQ
810 820 830 840 850
KDASTQTMAV EGDTVRFRHE GTREPWGEQP TDAVSSAERQ PESSRRMPGR
860 870 880 890 900
QAAALSFPRG TEKDVKKSRL PILIKPSRSL GSVCRLPAPQ EVVAQQQGEL
910 920 930 940 950
KEFKIRNKQR HQKLILAEAV MEGRPAPDKA LLKAQPLVGA AYRDSPGERE
960 970 980 990 1000
GPQATPCVWR DKERDEDQQA SCETDSEIYQ PDDLAIFPPC EEHPSEDFPG
1010 1020 1030 1040 1050
PTSVATYLSP KSQFSAKVSV VETNQLENSD TSNDKETLKR KICDLETELE
1060 1070 1080 1090 1100
VYRNFILQLQ KHSQFSEAIV TVLCGREGAQ DGLNKSKGST DEEEVTFSRL
1110 1120 1130 1140 1150
HQVRYVKHMK LLHLLAPEMI DGRALESLRL QLVDREYELQ KEQNLNLELF
1160 1170 1180 1190 1200
GEIHNLQNKF RDLSPSRYDS LVQAQARELS LQRQQIKDSH GICVVYRRHM
1210 1220 1230 1240 1250
NTMIKAFEEL LQASDVDCRV AEGFQEQLNQ CAELLKQLEK LFLKGNSVEV
1260 1270 1280 1290 1300
AMNTQEELRE RIEEDNLSYQ HILPESPAPS ASRALSDCHV LSDCEMSEKS
1310 1320 1330 1340 1350
SFSREQKQDS ETEKTSVLAN NVSHDLLMEH IQEIRSLRKR LEESIKTNEK
1360 1370 1380 1390 1400
LRRQLERQGS EVDQGFSNIF AYGSELHNSL TSEICFLRKQ NEALNAMLAK
1410 1420 1430 1440 1450
GSRDQQKENE KLRASLSRKT AGLEHLRREF ACVRAENDRL QRAVGEKESE
1460 1470 1480 1490 1500
NQRLLREVCH GRSELSRVQE EVKVRQQLLA QNDQLLQSLR VELKVYEKLD
1510 1520 1530 1540 1550
EEHRRPRETR AEASGEGWRG QDPSGHLHGL LTEIQALRAQ LERSIETNSA
1560 1570 1580 1590 1600
LQSRREEQLV QGGEEAQEAD LTLALQTLSV PERPLQLDKP DGDKCPVAAD
1610 1620 1630 1640 1650
NSYDLFDSTP AVPPRSASET PPLSANDMDT LSCDSGGSIT SASDMSRLVP
1660 1670 1680 1690 1700
GHRLWASTSG CHVLGLTEDY DALCEQVGRG QKLLAEMDMR IQEAPSPTSQ
1710 1720 1730 1740 1750
ELATKRPHAA PRSSFVAGVG AARLSLDEAS RLLTLLWRVS LPTSGQGALR
1760 1770 1780 1790 1800
CEQTGELKAE ISKLHKKLFE QEKKLQNTMK LLQLSKNQEK VIFDQLVVTH
1810 1820 1830
KVLRKARGNL EARECPSWNV QSQQARLLRR TFSQ
Length:1,834
Mass (Da):208,365
Last modified:November 7, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC791A9D9A4832429
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 7 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A383ZTD5A0A383ZTD5_BALAS
CDK5 regulatory subunit-associated ...
CDK5RAP2
1,898Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A383ZSV6A0A383ZSV6_BALAS
CDK5 regulatory subunit-associated ...
CDK5RAP2
1,902Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A383ZSX5A0A383ZSX5_BALAS
CDK5 regulatory subunit-associated ...
CDK5RAP2
1,868Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A383ZSV2A0A383ZSV2_BALAS
CDK5 regulatory subunit-associated ...
CDK5RAP2
1,875Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A383ZSU7A0A383ZSU7_BALAS
CDK5 regulatory subunit-associated ...
CDK5RAP2
1,907Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A383ZSY1A0A383ZSY1_BALAS
CDK5 regulatory subunit-associated ...
CDK5RAP2
1,870Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A383ZTE0A0A383ZTE0_BALAS
CDK5 regulatory subunit-associated ...
CDK5RAP2
1,661Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_007178187.1, XM_007178125.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
103013900

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_007178187.1, XM_007178125.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi103013900

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55755

Family and domain databases

InterProiView protein in InterPro
IPR012943 Cnn_1N
PfamiView protein in Pfam
PF07989 Cnn_1N, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A383ZSS7_BALAS
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A383ZSS7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 7, 2018
Last sequence update: November 7, 2018
Last modified: February 13, 2019
This is version 4 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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