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Protein

Cell division protein FtsA

Gene

ftsA

Organism
Shigella sp.
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.UniRule annotation

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell cycle, Cell divisionUniRule annotationImported

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Cell division protein FtsAUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ftsAUniRule annotation
ORF Names:DC037_17650Imported, DCS40_06330Imported, DCW67_18320Imported, DCW69_05480Imported, DCW70_04290Imported, DCW75_18180Imported, DCW77_19705Imported, DCW79_21350Imported, DCW81_14870Imported, DCW85_14555Imported, DCZ64_05830Imported, DCZ66_03360Imported, DCZ67_14170Imported, DD419_14425Imported, DD428_19935Imported, DD463_00430Imported, DD772_04815Imported, DDZ00_08185Imported, DDZ03_02230Imported, DEA93_19025Imported, DEF09_18075Imported, DEF15_17640Imported, DEF29_00870Imported, DEF31_09260Imported, DEF71_05120Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiShigella sp.Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri625 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeShigella

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell membraneUniRule annotation, Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with FtsZ.UniRule annotation
Self-interacts. Interacts with FtsZ.UniRule annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini10 – 196FtsAInterPro annotationAdd BLAST187

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili51 – 71Sequence analysisAdd BLAST21

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FtsA/MreB family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

HAMAP database of protein families

More...
HAMAPi
MF_02033 FtsA, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR020823 Cell_div_FtsA
IPR003494 SHS2_FtsA

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02491 SHS2_FTSA, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF003101 FtsA, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00842 FtsA, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01174 ftsA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A350HU21-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIKATDRKLV VGLEIGTAKV AALVGEVLPD GMVNIIGVGS CPSRGMDKGG
60 70 80 90 100
VNDLESVVKC VQRAIDQAEL MADCQISSVY LALSGKHISC QNEIGMVPIS
110 120 130 140 150
EEEVTQEDVE NVVHTAKSVR VRDEHRVLHV IPQEYAIDYQ EGIKNPVGLS
160 170 180 190 200
GVRMQAKVHL ITCHNDMAKN IVKAVERCGL KVDQLIFAGL ASSYSVLTED
210 220 230 240 250
ERELGVCVVD IGGGTMDIAV YTGGALRHTK VIPYAGNVVT SDIAYAFGTP
260 270 280 290 300
PSDAEAIKVR HGCALGSIVG KDESVEVPSV GGRPPRSLQR QTLAEVIEPR
310 320 330 340 350
YTELLNLVNE EILQLQEKLR QQGVKHHLAA GIVLTGGAAQ IEGLAACAQR
360 370 380 390 400
VFHTQVRIGA PLNITGLTDY AQEPYYSTAV GLLHYGKESH LNGEAEVEKR
410 420
VTASVGSWIK RLNSWLRKEF
Length:420
Mass (Da):45,330
Last modified:November 7, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC2475377A229B982
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
DMWL01000033 Genomic DNA Translation: HAS65742.1
DNAJ01000055 Genomic DNA Translation: HAU47132.1
DNAL01000044 Genomic DNA Translation: HAU63999.1
DNAG01000054 Genomic DNA Translation: HAU73336.1
DNAM01000051 Genomic DNA Translation: HAV85553.1
DNAO01000072 Genomic DNA Translation: HAV99037.1
DNAK01000023 Genomic DNA Translation: HAW66209.1
DNAH01000041 Genomic DNA Translation: HAZ71368.1
DNAI01000009 Genomic DNA Translation: HAZ81934.1
DNJZ01000038 Genomic DNA Translation: HBA76418.1
DNJT01000009 Genomic DNA Translation: HBA78721.1
DNMV01000045 Genomic DNA Translation: HBC13065.1
DNJY01000011 Genomic DNA Translation: HBC65511.1
DNWV01000045 Genomic DNA Translation: HBJ56361.1
DNWX01000035 Genomic DNA Translation: HBJ63270.1
DOBB01000047 Genomic DNA Translation: HBM20329.1
DOCO01000002 Genomic DNA Translation: HBN64924.1
DOBK01000052 Genomic DNA Translation: HBN72687.1
DOHU01000021 Genomic DNA Translation: HBQ69950.1
DOKS01000075 Genomic DNA Translation: HBS97714.1
DOOJ01000060 Genomic DNA Translation: HBU72289.1
DONY01000075 Genomic DNA Translation: HBV29749.1
DOOW01000002 Genomic DNA Translation: HBV33897.1
DOOM01000061 Genomic DNA Translation: HBV72524.1
DOQD01000144 Genomic DNA Translation: HBW44263.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
DMWL01000033 Genomic DNA Translation: HAS65742.1
DNAJ01000055 Genomic DNA Translation: HAU47132.1
DNAL01000044 Genomic DNA Translation: HAU63999.1
DNAG01000054 Genomic DNA Translation: HAU73336.1
DNAM01000051 Genomic DNA Translation: HAV85553.1
DNAO01000072 Genomic DNA Translation: HAV99037.1
DNAK01000023 Genomic DNA Translation: HAW66209.1
DNAH01000041 Genomic DNA Translation: HAZ71368.1
DNAI01000009 Genomic DNA Translation: HAZ81934.1
DNJZ01000038 Genomic DNA Translation: HBA76418.1
DNJT01000009 Genomic DNA Translation: HBA78721.1
DNMV01000045 Genomic DNA Translation: HBC13065.1
DNJY01000011 Genomic DNA Translation: HBC65511.1
DNWV01000045 Genomic DNA Translation: HBJ56361.1
DNWX01000035 Genomic DNA Translation: HBJ63270.1
DOBB01000047 Genomic DNA Translation: HBM20329.1
DOCO01000002 Genomic DNA Translation: HBN64924.1
DOBK01000052 Genomic DNA Translation: HBN72687.1
DOHU01000021 Genomic DNA Translation: HBQ69950.1
DOKS01000075 Genomic DNA Translation: HBS97714.1
DOOJ01000060 Genomic DNA Translation: HBU72289.1
DONY01000075 Genomic DNA Translation: HBV29749.1
DOOW01000002 Genomic DNA Translation: HBV33897.1
DOOM01000061 Genomic DNA Translation: HBV72524.1
DOQD01000144 Genomic DNA Translation: HBW44263.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

HAMAPiMF_02033 FtsA, 1 hit
InterProiView protein in InterPro
IPR020823 Cell_div_FtsA
IPR003494 SHS2_FtsA
PfamiView protein in Pfam
PF02491 SHS2_FTSA, 1 hit
PIRSFiPIRSF003101 FtsA, 1 hit
SMARTiView protein in SMART
SM00842 FtsA, 1 hit
TIGRFAMsiTIGR01174 ftsA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A350HU21_9ENTR
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A350HU21
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 7, 2018
Last sequence update: November 7, 2018
Last modified: December 5, 2018
This is version 2 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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