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UniProtKB - A0A340WFV8 (A0A340WFV8_LIPVE)

Entry version 12 (10 Feb 2021)
Sequence version 1 (10 Oct 2018)
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Protein
Submitted name:

kinectin isoform X1

Gene

KTN1

Organism
Lipotes vexillifer (Yangtze river dolphin)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
kinectin isoform X1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:KTN1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiLipotes vexillifer (Yangtze river dolphin)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri118797 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Artiodactyla › Whippomorpha › Cetacea › Odontoceti › Lipotidae › Lipotes
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000265300 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei7 – 29HelicalSequence analysisAdd BLAST23

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini29 – 128Rib_recp_KP_regInterPro annotationAdd BLAST100

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni48 – 81DisorderedSequence analysisAdd BLAST34
Regioni108 – 132DisorderedSequence analysisAdd BLAST25
Regioni146 – 219DisorderedSequence analysisAdd BLAST74

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili335 – 369Sequence analysisAdd BLAST35
Coiled coili406 – 433Sequence analysisAdd BLAST28
Coiled coili442 – 497Sequence analysisAdd BLAST56
Coiled coili565 – 592Sequence analysisAdd BLAST28
Coiled coili603 – 721Sequence analysisAdd BLAST119
Coiled coili731 – 754Sequence analysisAdd BLAST24
Coiled coili759 – 786Sequence analysisAdd BLAST28
Coiled coili797 – 852Sequence analysisAdd BLAST56
Coiled coili863 – 921Sequence analysisAdd BLAST59
Coiled coili929 – 984Sequence analysisAdd BLAST56
Coiled coili995 – 1036Sequence analysisAdd BLAST42
Coiled coili1116 – 1164Sequence analysisAdd BLAST49
Coiled coili1176 – 1276Sequence analysisAdd BLAST101
Coiled coili1333 – 1353Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi63 – 81PolyampholyteSequence analysisAdd BLAST19
Compositional biasi163 – 187PolyampholyteSequence analysisAdd BLAST25
Compositional biasi195 – 219PolyampholyteSequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR024854, Kinectin
IPR007794, Rib_rcpt_KP

The PANTHER Classification System

More...PANTHERi		PTHR18864, PTHR18864, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF05104, Rib_recp_KP_reg, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

A0A340WFV8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEFYESTYFI VLIPSVVITV IFLFFWLFMK ETLYDEVLAK QKREQKLIPT 
        60         70         80         90        100
KTDKKKAEKK KNKKKELQNG NLHESDSESV PRDFKLSDAL AVEDEQVVPV 
       110        120        130        140        150
PLNVVESSSS VRERKKKEKK HKPVLEEQVT KESDVSKIIP CKKVEPVPVT 
       160        170        180        190        200
KQPTPPLEAT ASKKKPGQKK SKNGSDDQDK KVEPLMAPSK KQESLPLHQE 
       210        220        230        240        250
TKQEGGSGKK KVSSKKQKTE NVLVDEPLIH ATTYIPLMDN ADSNPVVDKR 
       260        270        280        290        300
EVIDLIKPDQ VEGIQKTGAK KLKIEADKEN AEVKFKDFLL SLKTMMFSED 
       310        320        330        340        350
EALCVVDLLK EKSGVIQDAL KKSNKGELTA LVHQLQEKDK LLTALKEDAA 
       360        370        380        390        400
ALKDRCKQLT QEMMAEKERS NVVIARMKDR IGTLEKEHNV FQSKMHVSYQ 
       410        420        430        440        450
ETQQMQMKFQ QVREQMEAEI AHLKQENGIL RDAVSNTTNQ LESKQSAELN 
       460        470        480        490        500
KLRQDYARLV NELTEKTGKL QQEEVQKKNA EQAVTQLKVQ LQEAERRWEE 
       510        520        530        540        550
VQSYIRKRTA EHEAAQQDLQ SKFVAKENEV QSLHSKLTDT LVSKQQLEQR 
       560        570        580        590        600
LMQLMESEQK RVNKEESLQM QVQDILEQNE ALKAQIQQFH SQIAAQTSAS 
       610        620        630        640        650
ALAEELHKVI AEKDKQIKQT EDSLANEHDH LASKEEELKD IQNMNFLLKA 
       660        670        680        690        700
EVQKLQALAN EQAAAAHELE KMQKSIHVKD DKIRLLEEQL QCEISNKMEE 
       710        720        730        740        750
FKILNDQKKA LQLEVQKLQT LISEQPKKDV LEQMERCIQE KDEKLKTVEE 
       760        770        780        790        800
LLETGLIQVA TKEEELNAIR TENSSLTKEV QDLKAKQNDQ VSFASLVEEL 
       810        820        830        840        850
KKVIHEKDGK IKSVEELLEA ELLKVANKEK TIQDLKQEIE ALKEEIGNIQ 
       860        870        880        890        900
LEKAQQLSIT SQVQELQNLL KGKEEQMNTM KTVLEEKEKD LANKRKWLQD 
       910        920        930        940        950
LQEENESLKA HVQEVAQHNL REACSASRFE ELEIVLKEKE NEMKKLETVL 
       960        970        980        990       1000
KERESDLSRK TKLLQEVQDE NKLFKSQIEE LKQQNCQQAS SFPPHEELLK 
      1010       1020       1030       1040       1050
VISEREKEIT GLQNELVSLK DAVEHQRKKN NDLREKNWEA MEALASTEKM 
      1060       1070       1080       1090       1100
LQDKVNKTSK ERQQHVEAVE LEAKEVLKKL FPKVSVPSNL SYSEWLHGFE 
      1110       1120       1130       1140       1150
KRAKECVAGT SGSEEVKVLE HKLKEADEMH TLLQLECEKY KSVLAETEGI 
      1160       1170       1180       1190       1200
LQKLQRSVEQ EENKWKVKVD ESQKTIKQMQ LSFTSSEQEL ERLRRENKDT 
      1210       1220       1230       1240       1250
ENLRREREHL EMELEKAEME RSTYVTEVRE LKDLLTELQK KLDDSYSEAV 
      1260       1270       1280       1290       1300
RQNEELNLLK KQLNETLAKL RTEQSERQKV AGDLHKAQQS LDLIQSKIVK 
      1310       1320       1330       1340       1350
AAGDTTVIEN SDVSRETESS EKETMSVSLN QTVTQLQQLL QAVNQQLTKE 
      1360       1370       1380       1390       1400
KEHYQILGSS TSVVLRSVVC SALGIAGVLP RTPKGQNYFD NTKMLFAFFA 

DGVKTSR
Length:1,407
Mass (Da):161,992
Last modified:October 10, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i634DE35F5C483AE7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A340W9F3A0A340W9F3_LIPVE
kinectin isoform X5
KTN1
1,303Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A340WBY4A0A340WBY4_LIPVE
kinectin isoform X3
KTN1
1,330Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A340WEP2A0A340WEP2_LIPVE
kinectin isoform X4
KTN1
1,307Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A340WFW3A0A340WFW3_LIPVE
kinectin isoform X6
KTN1
1,301Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A340WG89A0A340WG89_LIPVE
kinectin isoform X2
KTN1
1,358Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_007446049.1, XM_007445987.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		103078498

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		lve:103078498

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_007446049.1, XM_007445987.1

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

GeneIDi103078498
KEGGilve:103078498

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		3895

Family and domain databases

InterProiView protein in InterPro
IPR024854, Kinectin
IPR007794, Rib_rcpt_KP
PANTHERiPTHR18864, PTHR18864, 1 hit
PfamiView protein in Pfam
PF05104, Rib_recp_KP_reg, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A340WFV8_LIPVE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A340WFV8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: October 10, 2018
Last sequence update: October 10, 2018
Last modified: February 10, 2021
This is version 12 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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