UniProtKB - A0A338P6L7 (A0A338P6L7_MOUSE)
Protein
Submitted name:
Transmembrane protease serine 2
Gene
Tmprss2
Organism
Mus musculus (Mouse)
Status
Functioni
Caution
Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation
GO - Molecular functioni
- scavenger receptor activity Source: InterPro
- serine-type peptidase activity Source: UniProtKB-KW
Keywordsi
Molecular function | Hydrolase, Protease, Serine proteaseARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: Transmembrane protease serine 2Imported |
Gene namesi | Name:Tmprss2Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1354381, Tmprss2 |
Subcellular locationi
Other locations
- membrane Source: InterPro
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 37 – 68 | SRCRInterPro annotationAdd BLAST | 32 |
Phylogenomic databases
GeneTreei | ENSGT00940000155207 |
Family and domain databases
CDDi | cd00112, LDLa, 1 hit |
Gene3Di | 3.10.250.10, 1 hit 4.10.400.10, 1 hit |
InterProi | View protein in InterPro IPR036055, LDL_receptor-like_sf IPR002172, LDrepeatLR_classA_rpt IPR001190, SRCR IPR017448, SRCR-like_dom IPR036772, SRCR-like_dom_sf |
Pfami | View protein in Pfam PF00057, Ldl_recept_a, 1 hit PF15494, SRCR_2, 1 hit |
SUPFAMi | SSF56487, SSF56487, 1 hit SSF57424, SSF57424, 1 hit |
PROSITEi | View protein in PROSITE PS50287, SRCR_2, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
A0A338P6L7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
SSGTCISSSL WCDGVAHCPN GEDENRCVRL YGQSFILQVY SSQRKAWYPV
60 70 80 90
CQDDWSESYG RAACKDMGYK VLSAGEPHPD YGSHEVWQAL SLGREL
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ9JIQ8 | TMPS2_MOUSE | Transmembrane protease serine 2 | Tmprss2 | 490 | Annotation score: | ||
A0A338P779 | A0A338P779_MOUSE | Transmembrane protease serine 2 | Tmprss2 | 103 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 1 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CT009632 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSMUST00000231544; ENSMUSP00000156007; ENSMUSG00000000385 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CT009632 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 2685, 293 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000231544; ENSMUSP00000156007; ENSMUSG00000000385 |
Organism-specific databases
MGIi | MGI:1354381, Tmprss2 |
Phylogenomic databases
GeneTreei | ENSGT00940000155207 |
Miscellaneous databases
ChiTaRSi | Tmprss2, mouse |
SOURCEi | Search... |
Gene expression databases
ExpressionAtlasi | A0A338P6L7, baseline and differential |
Family and domain databases
CDDi | cd00112, LDLa, 1 hit |
Gene3Di | 3.10.250.10, 1 hit 4.10.400.10, 1 hit |
InterProi | View protein in InterPro IPR036055, LDL_receptor-like_sf IPR002172, LDrepeatLR_classA_rpt IPR001190, SRCR IPR017448, SRCR-like_dom IPR036772, SRCR-like_dom_sf |
Pfami | View protein in Pfam PF00057, Ldl_recept_a, 1 hit PF15494, SRCR_2, 1 hit |
SUPFAMi | SSF56487, SSF56487, 1 hit SSF57424, SSF57424, 1 hit |
PROSITEi | View protein in PROSITE PS50287, SRCR_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A338P6L7_MOUSE | |
Accessioni | A0A338P6L7Primary (citable) accession number: A0A338P6L7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | October 10, 2018 |
Last sequence update: | October 10, 2018 | |
Last modified: | February 10, 2021 | |
This is version 14 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |