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UniProtKB - A0A2Y9RWE0 (A0A2Y9RWE0_TRIMA)
Protein
Submitted name:
ankyrin-2 isoform X10
Gene
LOC101354866
Organism
Trichechus manatus latirostris (Florida manatee)
Status
Names & Taxonomyi
Protein namesi | Submitted name: ankyrin-2 isoform X10Imported |
Gene namesi | Name:LOC101354866Imported |
Organismi | Trichechus manatus latirostris (Florida manatee)Imported |
Taxonomic identifieri | 127582 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Afrotheria › Sirenia › Trichechidae › Trichechus › |
Proteomesi |
|
Subcellular locationi
Cytoskeleton
- cytoskeleton ARBA annotation
Other locations
- Membrane ARBA annotation
Cytoskeleton
- cytoskeleton Source: UniProtKB-SubCell
Other locations
- membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cytoplasm, CytoskeletonARBA annotationStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 78 – 110 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 111 – 143 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 144 – 176 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 247 – 279 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 280 – 312 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 313 – 345 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 346 – 378 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 379 – 411 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 412 – 444 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 445 – 477 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 478 – 510 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 511 – 543 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 544 – 576 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 577 – 609 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 610 – 642 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 643 – 675 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 676 – 708 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 709 – 741 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 742 – 774 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Repeati | 775 – 807 | ANKPROSITE-ProRule annotationAdd BLAST | 33 | |
Domaini | 983 – 1171 | ZU5InterPro annotationAdd BLAST | 189 | |
Domaini | 1173 – 1319 | ZU5InterPro annotationAdd BLAST | 147 | |
Domaini | 1499 – 1583 | DeathInterPro annotationAdd BLAST | 85 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 19 – 49 | DisorderedSequence analysisAdd BLAST | 31 | |
Regioni | 1472 – 1497 | DisorderedSequence analysisAdd BLAST | 26 | |
Regioni | 1620 – 1641 | DisorderedSequence analysisAdd BLAST | 22 | |
Regioni | 1706 – 1819 | DisorderedSequence analysisAdd BLAST | 114 | |
Regioni | 1842 – 1864 | DisorderedSequence analysisAdd BLAST | 23 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 19 – 48 | Basic and acidic residuesSequence analysisAdd BLAST | 30 | |
Compositional biasi | 1706 – 1730 | Polar residuesSequence analysisAdd BLAST | 25 | |
Compositional biasi | 1737 – 1753 | Polar residuesSequence analysisAdd BLAST | 17 | |
Compositional biasi | 1784 – 1819 | Basic and acidic residuesSequence analysisAdd BLAST | 36 |
Keywords - Domaini
ANK repeatPROSITE-ProRule annotationFamily and domain databases
Gene3Di | 1.10.533.10, 1 hit 1.25.40.20, 3 hits |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR036770, Ankyrin_rpt-contain_sf IPR040745, Ankyrin_UPA IPR011029, DEATH-like_dom_sf IPR000488, Death_domain IPR000906, ZU5_dom |
Pfami | View protein in Pfam PF00023, Ank, 2 hits PF12796, Ank_2, 6 hits PF13637, Ank_4, 2 hits PF00531, Death, 1 hit PF17809, UPA_2, 1 hit PF00791, ZU5, 2 hits |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 23 hits SM00005, DEATH, 1 hit SM00218, ZU5, 1 hit |
SUPFAMi | SSF47986, SSF47986, 1 hit SSF48403, SSF48403, 3 hits |
PROSITEi | View protein in PROSITE PS50088, ANK_REPEAT, 20 hits PS50017, DEATH_DOMAIN, 1 hit PS51145, ZU5, 2 hits |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 23 potential isoforms that are computationally mapped.Show allAlign All
A0A2Y9RWE0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAHAAASIKK VREAELDEKE KILERERKKQ RKIPRERMER KRKSDSNASF
60 70 80 90 100
LRAARAGNLD KVVEYLKGGI DINTCNQNGL NALHLAAKEG HVGLVQELLG
110 120 130 140 150
RGSAVDSATK KGNTALHIAS LAGQAEVVKV LVKEGANINA QSQNGFTPLY
160 170 180 190 200
MAAQENHIDV VKYLLENGAN QSTATEDGFT PLAVALQQGH NQAVAILLEN
210 220 230 240 250
DTKGKVRLPA LHIAARKDDT KSAALLLQND HNADVQSKMM ANRTTESGFT
260 270 280 290 300
PLHIAAHYGN VNVATLLLNR GAAVDFTARN GITPLHVASK RGNTNMVKLL
310 320 330 340 350
LDRGGQIDAK TRDGLTPLHC AARSGHDQVV ELLLERGAPL LARTKNGLSP
360 370 380 390 400
LHMAAQGDHV ECVKHLLQHK APVDDVTLDY LTALHVAAHC GHYRVTKLLL
410 420 430 440 450
DKRANPNARA LNGFTPLHIA CKKNRIKVME LLVKYGASIQ AITESGLTPI
460 470 480 490 500
HVAAFMGHLN IVLLLLQNGA SPDVTNIRGE TALHMAARAG QVEVVRCLLR
510 520 530 540 550
NGALVDARAR EEQTPLHIAS RLGKTEIVQL LLQHMAHPDA ATTNGYTPLH
560 570 580 590 600
ISAREGQVDV ASVLLEAGAA HSLATKKGFT PLHVAAKYGS LDVAKLLLQR
610 620 630 640 650
RAAADSAGKN GLTPLHVAAH YDNQKVALLL LEKGASPHAT AKNGYTPLHI
660 670 680 690 700
AAKKNQMQIA STLLNYGAET NIVTKQGVTP LHLASQEGHT DMVTLLLDKG
710 720 730 740 750
ANIHTATKSG LTSLHLAAQE DKVNVADILT KHGADQDAHT KLGYTPLIVA
760 770 780 790 800
CHYGNVKMVN FLLKQGANVN AKTKNGYTPL HQAAQQGHTH IINVLLQHGA
810 820 830 840 850
KPNATTANGN TALAIAKRLG YISVVDTLKV VTEEVTTTTT TITEKHKLNV
860 870 880 890 900
PETMTEVLDV SDEEGDDTMT GDGGEYLRPE DLKELGDDSL PSSQFLDGMN
910 920 930 940 950
YLRYSLEGGR SDSLRSFSSD RSHTLSHASY LRDSAMIDDT VVIPSHQVST
960 970 980 990 1000
LAKEAERNSY RLSWGTENLD NVALSSSPIH SGFLVSFMVD ARGGAMRGCR
1010 1020 1030 1040 1050
HNGLRIIIPP RKCTAPTRVT CRLVKRHRLA TMPPMVEGEG LASRLIEVGP
1060 1070 1080 1090 1100
SGAQFLGKLH LPTAPPPLNE GESLVSRILQ LGPPGTKFLG PVIVEIPHFA
1110 1120 1130 1140 1150
ALRGKERELV VLRSENGDSW KEHYCEYTED ELNEILNGMD EVLDSPEDLE
1160 1170 1180 1190 1200
KKRICRIITR DFPQYFAVVS RIKQDSNLIG PEGGVLSSTV VPQVQAVFPE
1210 1220 1230 1240 1250
GALTKRIRVG LQAQPMHSEL VKKILGNKAT FSPIVTLEPR RRKFHKPITM
1260 1270 1280 1290 1300
TIPVPKAASD VMLNGFGGDA PTLRLLCSIT GGTTPAQWED ITGTTPLTFV
1310 1320 1330 1340 1350
NECVSFTTNV SARFWLIDCR QIQESVTFAS QVYREIICVP YMAKFVVFAK
1360 1370 1380 1390 1400
SHDPIEARLR CFCMTDDKVD KTLEQQENFA EVARSRDVEV LEGKPIYVDC
1410 1420 1430 1440 1450
FGNLVPLTKS GQHHIFSFFA FKENRLPLFV KVRDTTQEPC GRLSFMKEPK
1460 1470 1480 1490 1500
STRGLVHQAI CNLNITLPVY TKESESDQEQ EEEIDMTSEK NPQDEQERIE
1510 1520 1530 1540 1550
ERLAYIADHL GFSWTELARE LDFTEEQIHQ IRIENPNSLQ DQSHALLKYW
1560 1570 1580 1590 1600
LERDGKHATD TGLIECLTKI NRMDIVHLME ASTEPFQERI SHSYAEIEQT
1610 1620 1630 1640 1650
ITLDHSEGFS VLQEELCTAQ HKQKEEQPES KESETCDCPP IVSEEDISVG
1660 1670 1680 1690 1700
YSMFQDYIPK TEGDTSAAEL LSQTDKEQVQ QDFSGKMQDL TEESSLEHQQ
1710 1720 1730 1740 1750
EYFVTTPGTE VSETLKSPVV SGSPSKIPEE ISTPSEEERP YLQTPTSSEW
1760 1770 1780 1790 1800
GGSPIVQEPE ESPVQREESS PRRTSLVIVE SADDQPRIFE RPDEDVAFQK
1810 1820 1830 1840 1850
GDDMPDIPPE TVTEEKYTDE HGHTVVKKVT RKIIRRYVSS DGTEKEEITM
1860 1870 1880
QGMPQEPVNI EEGDDYSKVI KRVVLKSDTE QSEDNDE
Computationally mapped potential isoform sequencesi
There are 23 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A2Y9E2G2 | A0A2Y9E2G2_TRIMA | ankyrin-2 isoform X1 | LOC101354866 | 3,958 | Annotation score: | ||
A0A2Y9E3X6 | A0A2Y9E3X6_TRIMA | ankyrin-2 isoform X13 | LOC101354866 | 1,872 | Annotation score: | ||
A0A2Y9RLE1 | A0A2Y9RLE1_TRIMA | ankyrin-2 isoform X2 | LOC101354866 | 1,937 | Annotation score: | ||
A0A2Y9RLE4 | A0A2Y9RLE4_TRIMA | ankyrin-2 isoform X7 | LOC101354866 | 1,902 | Annotation score: | ||
A0A2Y9RLE7 | A0A2Y9RLE7_TRIMA | ankyrin-2 isoform X12 | LOC101354866 | 1,879 | Annotation score: | ||
A0A2Y9RLF3 | A0A2Y9RLF3_TRIMA | ankyrin-2 isoform X18 | LOC101354866 | 1,801 | Annotation score: | ||
A0A2Y9RN98 | A0A2Y9RN98_TRIMA | ankyrin-2 isoform X4 | LOC101354866 | 1,926 | Annotation score: | ||
A0A2Y9RNA3 | A0A2Y9RNA3_TRIMA | ankyrin-2 isoform X9 | LOC101354866 | 1,898 | Annotation score: | ||
A0A2Y9RNA7 | A0A2Y9RNA7_TRIMA | ankyrin-2 isoform X15 | LOC101354866 | 1,839 | Annotation score: | ||
A0A2Y9RNB2 | A0A2Y9RNB2_TRIMA | ankyrin-2 isoform X19 | LOC101354866 | 1,772 | Annotation score: | ||
There are more potential isoformsShow all |
Sequence databases
RefSeqi | XP_023595968.1, XM_023740200.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
RefSeqi | XP_023595968.1, XM_023740200.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family and domain databases
Gene3Di | 1.10.533.10, 1 hit 1.25.40.20, 3 hits |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR036770, Ankyrin_rpt-contain_sf IPR040745, Ankyrin_UPA IPR011029, DEATH-like_dom_sf IPR000488, Death_domain IPR000906, ZU5_dom |
Pfami | View protein in Pfam PF00023, Ank, 2 hits PF12796, Ank_2, 6 hits PF13637, Ank_4, 2 hits PF00531, Death, 1 hit PF17809, UPA_2, 1 hit PF00791, ZU5, 2 hits |
PRINTSi | PR01415, ANKYRIN |
SMARTi | View protein in SMART SM00248, ANK, 23 hits SM00005, DEATH, 1 hit SM00218, ZU5, 1 hit |
SUPFAMi | SSF47986, SSF47986, 1 hit SSF48403, SSF48403, 3 hits |
PROSITEi | View protein in PROSITE PS50088, ANK_REPEAT, 20 hits PS50017, DEATH_DOMAIN, 1 hit PS51145, ZU5, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A2Y9RWE0_TRIMA | |
Accessioni | A0A2Y9RWE0Primary (citable) accession number: A0A2Y9RWE0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 12, 2018 |
Last sequence update: | September 12, 2018 | |
Last modified: | January 19, 2022 | |
This is version 14 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |