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Entry version 7 (13 Nov 2019)
Sequence version 1 (12 Sep 2018)
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Protein
Submitted name:

large proline-rich protein BAG6 isoform X5

Gene

LOC111152232

Organism
Enhydra lutris kenyoni
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
large proline-rich protein BAG6 isoform X5Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:LOC111152232Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEnhydra lutris kenyoniImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri391180 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaMustelidaeLutrinaeEnhydra
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000248482 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini19 – 79Ubiquitin-likeInterPro annotationAdd BLAST61

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni90 – 128DisorderedSequence analysisAdd BLAST39
Regioni188 – 269DisorderedSequence analysisAdd BLAST82
Regioni383 – 438DisorderedSequence analysisAdd BLAST56
Regioni458 – 488DisorderedSequence analysisAdd BLAST31
Regioni539 – 561DisorderedSequence analysisAdd BLAST23
Regioni593 – 636DisorderedSequence analysisAdd BLAST44
Regioni683 – 724DisorderedSequence analysisAdd BLAST42
Regioni975 – 1090DisorderedSequence analysisAdd BLAST116
Regioni1102 – 1165DisorderedSequence analysisAdd BLAST64

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi94 – 108PolarSequence analysisAdd BLAST15
Compositional biasi207 – 221PolarSequence analysisAdd BLAST15
Compositional biasi224 – 240PolyampholyteSequence analysisAdd BLAST17
Compositional biasi246 – 265Pro-richSequence analysisAdd BLAST20
Compositional biasi407 – 422PolarSequence analysisAdd BLAST16
Compositional biasi604 – 619PolarSequence analysisAdd BLAST16
Compositional biasi686 – 715Pro-richSequence analysisAdd BLAST30
Compositional biasi993 – 1007PolarSequence analysisAdd BLAST15

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR021925 BAG6
IPR000626 Ubiquitin-like_dom
IPR029071 Ubiquitin-like_domsf
IPR019954 Ubiquitin_CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12057 BAG6, 1 hit
PF00240 ubiquitin, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00213 UBQ, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54236 SSF54236, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00299 UBIQUITIN_1, 1 hit
PS50053 UBIQUITIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

A0A2Y9JZ92-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEPSDSTSTT TSMEEPDSLE VLVKTLDSQT RTFIVGAQMN VKEFKEHIAA
60 70 80 90 100
SVSIPSEKQR LIYQGRVLQD DKKLQEYNVG GKVIHLVERA PPQTQLPSGA
110 120 130 140 150
SSGIGSASAT HGGGPPPGTR GPGASVHDRN ANSYVMVGTF NLPSDGSAVD
160 170 180 190 200
VHINMEQAPI QSEPRVRLVM AQHMIRDIQT LLSRMECRGG PQAQHSQPPP
210 220 230 240 250
QTPTVVPEPG ALSSQTSEPV ESEVPPREPM EAEEVEERAP AQSPELTPSG
260 270 280 290 300
PAPVGPTPAP ETNAPNHPSP AEYVEVLQEL QRLESRLQPF LQRYYEVLGA
310 320 330 340 350
AATTDYNNNQ EGREEDQRLI NLVGESLRLL GNTFVALSDL RCNLACAPPR
360 370 380 390 400
HLHVVRPMSH YTTPMVLQQA AIPIQINVGT TVTMTGNGTR PPPAANAEAA
410 420 430 440 450
PPGPGQASSL APTSTTVESS TEGVPPPGPA PPPTTSHPRV IRISHQSVEP
460 470 480 490 500
VVMMHMNIQD SGTQPGGVPS APTGPLGPPG HGQTLGSTLI QLPSLPPEFM
510 520 530 540 550
HAVAHQITHQ AMVAAVASAA AGQQVPGFPT APTRVVIARP TPPQARPSHP
560 570 580 590 600
GGPPVSGTLQ GAGLGTNASL AQMVSGLVGQ LLMQPVLVAQ GTPGMAPPPA
610 620 630 640 650
PATASASAGT TNTATTAGPA PGGPAQPPPP QPSTADLQFS QLLGNLLGPA
660 670 680 690 700
GPGAGGSGMA SPTITVAMPG VPAFLQGMTD FLQATQTAPP PPPPPPPPPP
710 720 730 740 750
APEQQTMPPP GSPSGGAGSP GGLGLESLSP EFFTSVVQGV LNSLLGSLGA
760 770 780 790 800
RAGSSESIAA FIQRLSGSSN IFEPGADGAL GFFGALLSLL CQNFSMVDVV
810 820 830 840 850
MLLHGHFQPL QRLQPQLRSF FHQHYLGGQE PTPGNIRTAT HTLITGLEEY
860 870 880 890 900
VRESFSLVQV QPGVDIIRTN LEFLQEQFNS IAAHVLHCTD SGFGARLLEL
910 920 930 940 950
CNQGLFECLA LNLHCLGGQQ MELAAVINGR IRRMSRGVNP SLVSWLTTMM
960 970 980 990 1000
GLRLQVVLEH MPVGPDAILR YVRRVGDPPQ PLPEEPMEVQ GSERTSPEPQ
1010 1020 1030 1040 1050
RENASPAPGT TAEEAMSRGP PPAPEGGGSR DEQDGASAET EPWAAAVPPE
1060 1070 1080 1090 1100
WVPIIQQDIQ SQRKVKPQPP LSDAYLSGMP AKRRKTMQGE GPQLLLSEAV
1110 1120 1130 1140 1150
SRAAKAAGAR PLTSPESLSR DLEAPEVQES YRQQLRADIQ KRLQEDPNYS
1160
PQRFPNAHRA FADDP
Length:1,165
Mass (Da):122,604
Last modified:September 12, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF3002E0C8C40A5D4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2Y9JZ90A0A2Y9JZ90_ENHLU
large proline-rich protein BAG6 iso...
LOC111152232
1,164Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2Y9JZ00A0A2Y9JZ00_ENHLU
large proline-rich protein BAG6 iso...
LOC111152232
1,080Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2Y9JZ97A0A2Y9JZ97_ENHLU
large proline-rich protein BAG6 iso...
LOC111152232
1,079Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2Y9JZS3A0A2Y9JZS3_ENHLU
large proline-rich protein BAG6 iso...
LOC111152232
1,128Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2Y9K3X5A0A2Y9K3X5_ENHLU
large proline-rich protein BAG6 iso...
LOC111152232
1,147Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2Y9K3X9A0A2Y9K3X9_ENHLU
large proline-rich protein BAG6 iso...
LOC111152232
1,111Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2Y9KA62A0A2Y9KA62_ENHLU
large proline-rich protein BAG6 iso...
LOC111152232
1,129Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2Y9KA67A0A2Y9KA67_ENHLU
large proline-rich protein BAG6 iso...
LOC111152232
1,097Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_022366363.1, XM_022510655.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_022366363.1, XM_022510655.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

InterProiView protein in InterPro
IPR021925 BAG6
IPR000626 Ubiquitin-like_dom
IPR029071 Ubiquitin-like_domsf
IPR019954 Ubiquitin_CS
PfamiView protein in Pfam
PF12057 BAG6, 1 hit
PF00240 ubiquitin, 1 hit
SMARTiView protein in SMART
SM00213 UBQ, 1 hit
SUPFAMiSSF54236 SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS00299 UBIQUITIN_1, 1 hit
PS50053 UBIQUITIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2Y9JZ92_ENHLU
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2Y9JZ92
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 12, 2018
Last sequence update: September 12, 2018
Last modified: November 13, 2019
This is version 7 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
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