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Entry version 7 (05 Jun 2019)
Sequence version 1 (12 Sep 2018)
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Protein
Submitted name:

ankyrin-3 isoform X1

Gene

ANK3

Organism
Neomonachus schauinslandi (Hawaiian monk seal) (Monachus schauinslandi)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
ankyrin-3 isoform X1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ANK3Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiNeomonachus schauinslandi (Hawaiian monk seal) (Monachus schauinslandi)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri29088 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaPhocidaeNeomonachus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000248481 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini40 – 815ANK_REP_REGIONInterPro annotationAdd BLAST776
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati73 – 105ANKPROSITE-ProRule annotationAdd BLAST33
Repeati106 – 138ANKPROSITE-ProRule annotationAdd BLAST33
Repeati139 – 171ANKPROSITE-ProRule annotationAdd BLAST33
Repeati172 – 195ANKPROSITE-ProRule annotationAdd BLAST24
Repeati234 – 266ANKPROSITE-ProRule annotationAdd BLAST33
Repeati267 – 299ANKPROSITE-ProRule annotationAdd BLAST33
Repeati300 – 332ANKPROSITE-ProRule annotationAdd BLAST33
Repeati333 – 365ANKPROSITE-ProRule annotationAdd BLAST33
Repeati366 – 398ANKPROSITE-ProRule annotationAdd BLAST33
Repeati399 – 431ANKPROSITE-ProRule annotationAdd BLAST33
Repeati432 – 464ANKPROSITE-ProRule annotationAdd BLAST33
Repeati465 – 497ANKPROSITE-ProRule annotationAdd BLAST33
Repeati498 – 530ANKPROSITE-ProRule annotationAdd BLAST33
Repeati531 – 563ANKPROSITE-ProRule annotationAdd BLAST33
Repeati564 – 596ANKPROSITE-ProRule annotationAdd BLAST33
Repeati597 – 629ANKPROSITE-ProRule annotationAdd BLAST33
Repeati630 – 662ANKPROSITE-ProRule annotationAdd BLAST33
Repeati663 – 695ANKPROSITE-ProRule annotationAdd BLAST33
Repeati696 – 728ANKPROSITE-ProRule annotationAdd BLAST33
Repeati729 – 761ANKPROSITE-ProRule annotationAdd BLAST33
Repeati762 – 794ANKPROSITE-ProRule annotationAdd BLAST33
Domaini984 – 1139ZU5InterPro annotationAdd BLAST156
Domaini1141 – 1288ZU5InterPro annotationAdd BLAST148
Domaini4103 – 4187DeathInterPro annotationAdd BLAST85

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 44DisorderedSequence analysisAdd BLAST44
Regioni1519 – 1540DisorderedSequence analysisAdd BLAST22
Regioni1967 – 1987DisorderedSequence analysisAdd BLAST21
Regioni2070 – 2092DisorderedSequence analysisAdd BLAST23
Regioni2107 – 2160DisorderedSequence analysisAdd BLAST54
Regioni2172 – 2264DisorderedSequence analysisAdd BLAST93
Regioni2299 – 2323DisorderedSequence analysisAdd BLAST25
Regioni2377 – 2433DisorderedSequence analysisAdd BLAST57
Regioni2474 – 2507DisorderedSequence analysisAdd BLAST34
Regioni2588 – 2753DisorderedSequence analysisAdd BLAST166
Regioni2796 – 2820DisorderedSequence analysisAdd BLAST25
Regioni2938 – 2960DisorderedSequence analysisAdd BLAST23
Regioni2988 – 3009DisorderedSequence analysisAdd BLAST22
Regioni3038 – 3072DisorderedSequence analysisAdd BLAST35
Regioni3130 – 3271DisorderedSequence analysisAdd BLAST142
Regioni3298 – 3443DisorderedSequence analysisAdd BLAST146
Regioni3455 – 3519DisorderedSequence analysisAdd BLAST65
Regioni3541 – 3617DisorderedSequence analysisAdd BLAST77
Regioni3638 – 3723DisorderedSequence analysisAdd BLAST86
Regioni3872 – 3898DisorderedSequence analysisAdd BLAST27
Regioni3922 – 3992DisorderedSequence analysisAdd BLAST71
Regioni4032 – 4104DisorderedSequence analysisAdd BLAST73
Regioni4337 – 4373DisorderedSequence analysisAdd BLAST37

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1 – 27PolyampholyteSequence analysisAdd BLAST27
Compositional biasi2112 – 2129PolyampholyteSequence analysisAdd BLAST18
Compositional biasi2130 – 2146PolarSequence analysisAdd BLAST17
Compositional biasi2219 – 2248PolyampholyteSequence analysisAdd BLAST30
Compositional biasi2403 – 2433PolarSequence analysisAdd BLAST31
Compositional biasi2588 – 2618PolyampholyteSequence analysisAdd BLAST31
Compositional biasi2619 – 2636PolarSequence analysisAdd BLAST18
Compositional biasi2643 – 2659PolyampholyteSequence analysisAdd BLAST17
Compositional biasi2680 – 2697PolyampholyteSequence analysisAdd BLAST18
Compositional biasi2700 – 2721PolarSequence analysisAdd BLAST22
Compositional biasi2731 – 2749PolyampholyteSequence analysisAdd BLAST19
Compositional biasi2988 – 3007PolarSequence analysisAdd BLAST20
Compositional biasi3042 – 3059PolarSequence analysisAdd BLAST18
Compositional biasi3130 – 3186PolarSequence analysisAdd BLAST57
Compositional biasi3225 – 3243PolyampholyteSequence analysisAdd BLAST19
Compositional biasi3334 – 3358PolyampholyteSequence analysisAdd BLAST25
Compositional biasi3380 – 3408PolarSequence analysisAdd BLAST29
Compositional biasi3465 – 3498PolyampholyteSequence analysisAdd BLAST34
Compositional biasi3548 – 3572PolyampholyteSequence analysisAdd BLAST25
Compositional biasi3579 – 3602PolarSequence analysisAdd BLAST24
Compositional biasi3653 – 3675PolarSequence analysisAdd BLAST23
Compositional biasi3684 – 3698PolarSequence analysisAdd BLAST15
Compositional biasi3955 – 3992PolarSequence analysisAdd BLAST38
Compositional biasi4032 – 4047PolyampholyteSequence analysisAdd BLAST16
Compositional biasi4048 – 4065PolarSequence analysisAdd BLAST18
Compositional biasi4066 – 4090PolyampholyteSequence analysisAdd BLAST25
Compositional biasi4345 – 4364PolyampholyteSequence analysisAdd BLAST20

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeatPROSITE-ProRule annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 7 hits
cd08803 Death_ank3, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 3 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR037971 Ank3_Death
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR040745 Ankyrin_UPA
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR000906 ZU5_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00023 Ank, 2 hits
PF12796 Ank_2, 6 hits
PF13606 Ank_3, 1 hit
PF00531 Death, 1 hit
PF17809 UPA_2, 1 hit
PF00791 ZU5, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415 ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 22 hits
SM00005 DEATH, 1 hit
SM00218 ZU5, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47986 SSF47986, 1 hit
SSF48403 SSF48403, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 21 hits
PS50017 DEATH_DOMAIN, 1 hit
PS51145 ZU5, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2Y9HTU8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAHAASQLKK NRDLEINAEE EPEKKRKHRK RSRDRKKKSD ANASYLRAAR
60 70 80 90 100
AGHLEKALDY IKNGVDINIC NQNGLNALHL ASKEGHVEVV SELLQREANV
110 120 130 140 150
DAATKKGNTA LHIASLAGQA EVVKVLVTNG ANVNAQSQNG FTPLYMAAQE
160 170 180 190 200
NHLEVVKFLL DNGASQSLAT EDGFTPLAVA LQQGHDQVVS LLLENDTKGK
210 220 230 240 250
VRLPALHIAA RKDDTKAAAL LLQNDNNADV ESKSGFTPLH IAAHYGNINV
260 270 280 290 300
ATLLLNRAAA VDFTARNDIT PLHVASKRGN ANMVKLLLDR GAKIDAKTRD
310 320 330 340 350
GLTPLHCGAR SGHEQVVEML LDRAAPILSK TKNGLSPLHM ATQGDHLNCV
360 370 380 390 400
QLLLQHNVPV DDVTNDYLTA LHVAAHCGHY KVAKVLLDKK ANPNAKALNG
410 420 430 440 450
FTPLHIACKK NRIKVMELLL KHGASIQAVT ESGLTPIHVA AFMGHVNIVS
460 470 480 490 500
QLMHHGASPN TTNVRGETAL HMAARSGQAE VVRYLVQDGA QVEAKAKDDQ
510 520 530 540 550
TPLHISARLG KADIVQQLLQ QGASPNAATT SGYTPLHLSA REGHEDVAAF
560 570 580 590 600
LLDHGASLSI TTKKGFTPLH VAAKYGKLEV ANLLLQKSAS PDAAGKSGLT
610 620 630 640 650
PLHVAAHYDN QKVALLLLDQ GASPHAAAKN GYTPLHIAAK KNQMDIATTL
660 670 680 690 700
LEYGADANAV TRQGIASVHL AAQEGHVDMV SLLLGRNANV NLSNKSGLTP
710 720 730 740 750
LHLAAQEDRV NVAEVLVNQG ANVDAQTKMG YTPLHVGCHY GNIKIVNFLL
760 770 780 790 800
QHSAKVNAKT KNGYTPLHQA AQQGHTHIIN VLLQNNASPN ELTVNGNTAL
810 820 830 840 850
AIARRLGYIS VVDTLKVVTE ETMTTTTVIE KHKMNVPETM NEVLDMSDDE
860 870 880 890 900
VRKANAPEML SDGEYISDVE EGEDAMTGDT DKYLGPQDLK ELGDDSLPAE
910 920 930 940 950
GYMGFSLGAR SASLRSFSSD RSYTLNRSSY ARDSMMIEEL LVPSKEQHLT
960 970 980 990 1000
FTREFDSDSL RHYSWAADTL DNVNLVSSPV HSGFLVSFMV DARGGSMRGS
1010 1020 1030 1040 1050
RHHGMRIIIP PRKCTAPTRI TCRLVKRHKL ANPPPMVEGE GLASRLVEMG
1060 1070 1080 1090 1100
PAGAQFLGPV IVEIPHFGSM RGKERELIVL RSENGETWKE HQFDSKNEDL
1110 1120 1130 1140 1150
TELLNGMDEE LDSPEELGKK RICRIITKDF PQYFAVVSRI KQESNQIGPE
1160 1170 1180 1190 1200
GGILSSTTVP LVQASFPEGA LTKRIRVGLQ AQPVPDEIVK KILGNKATFS
1210 1220 1230 1240 1250
PIVTVEPRRR KFHKPITMTI PVPPPSGEGV ANGYKGDSTP NLRLLCSITG
1260 1270 1280 1290 1300
GTSPAQWEDI TGTTPLTFIK DCVSFTTNVS ARFWLADCHQ VLETVGLATQ
1310 1320 1330 1340 1350
LYRELICVPY MAKFVVFAKM NDPVESSLRC FCMTDDKVDK TLEQQENFEE
1360 1370 1380 1390 1400
VARSKDIEVL EGKPIYVDCY GNLAPLTKGG QQLVFNFYAF KENRLPFSIK
1410 1420 1430 1440 1450
IRDTSQEPCG RLSFLKEPKT TKGLPQTAVC NLNITLPAHK KETESDQDDE
1460 1470 1480 1490 1500
AEKADRRQSF ASLALRKRYS YLTEPGMIER SAGATRSLPT TYSYKPFFST
1510 1520 1530 1540 1550
RPYQSWTTAP ITVPGPAKSG FTSLSSSSSN TPSASPLKSI WSVSTPSPIK
1560 1570 1580 1590 1600
STLGASTTSS VKSISDVASP IRSFRTISSP IKTVVSQSPY NIQVSSGTLA
1610 1620 1630 1640 1650
RAPTVPEASP LKGLASNATY SSRTSPVTTA GSLLERSSIT MTPPASPKSN
1660 1670 1680 1690 1700
INMYSSSLPF KSIITSAAPL ISSPLKSVVS PAKSAVDVIS SAKVTMASSL
1710 1720 1730 1740 1750
SSPVKQMPGH TEVALVNGSI SPLKYPSSST LINGCKATAT LQEKISTATN
1760 1770 1780 1790 1800
SVSSMVNAAT DTVEKVFSTT TAMPFSPLRS YVSSTPSAFQ SLRTPSASAL
1810 1820 1830 1840 1850
YTSLGSSISA TTSSVTSSII TVPVYSVVNV LPEPALKKLP DSSSLTKSAA
1860 1870 1880 1890 1900
ALLSPIKTLT TETRPQPHFS RTSSPVKSSL FLAPSALKLS TPSSLSSSQE
1910 1920 1930 1940 1950
ILKDVAEMKE DLMRMTAILQ TDVPEEKPFP PELPKEGRID DEEPFKIVEK
1960 1970 1980 1990 2000
VKEDLVKVSE ILKKDVCVDN KGPPKSPKSD KGLSPEDDWI EFSSEEIREA
2010 2020 2030 2040 2050
RQQAAVSHPP SLPERVQVKA KAASEKDYNL TKVIDYLTND IGSSSLTNLK
2060 2070 2080 2090 2100
YKFEDAKKDG EERQKRILKP AIALQEHKLK MPPASMRPST SEKELCKMAD
2110 2120 2130 2140 2150
SFFGTDTILE SPDDFSQHDQ DKSPLSDSGF ETRSEKTPSA PQSAESTGPK
2160 2170 2180 2190 2200
PLFHEVPIPP VLTETRTEVV HVIRSYEPSA GDAPPGQPEE SVAPKPSPTF
2210 2220 2230 2240 2250
TELEPKPTTS SIKEKVKAFQ MKANGEEDDH SRVLSKGMRV KEETHITTTT
2260 2270 2280 2290 2300
RMVYHSPPGS EGTSERIEET MSVHDIMKAF QSGRDPSKEL AGLFEHKSAV
2310 2320 2330 2340 2350
PPDVHKSAAE TTAQHAEKDN QMKPKLERII EVHIEKGNQA EPTEVIIRET
2360 2370 2380 2390 2400
KKHPEKEMYV YQKDLSRGDI NLKDFLPEKH DAFPCPEEQG QQEEEELTAE
2410 2420 2430 2440 2450
ESLPSYLESS RVNTPVSQEE ESRPSSAQLI SDDSYKTLKL LSQHSIEYHD
2460 2470 2480 2490 2500
DELSELRGES YRFAEKMLLS EKLDVSHSDT EESVTDHAGP PSSELQGSDK
2510 2520 2530 2540 2550
RSREKVVTAP KKEILSKIYK DVSENGVGKV SKDEHFDKVT VLHYSGDVSS
2560 2570 2580 2590 2600
PKHAMWMRFT EDRLDRGREK LIYEDRVDRT VKEAEEKLTE VSQFFRDRTE
2610 2620 2630 2640 2650
KLNDELQSPE KKPRPRNGKE YSSQSSTSSS PEKVLLTELL ASSDERVRAK
2660 2670 2680 2690 2700
QHGHDGQGFP TADEKQAASL PSSPEKKGLS AQLEDSKPTE EVRESISQSK
2710 2720 2730 2740 2750
APEGPPSGFQ LKQSKLSSIR LKFEQGAQAK SKDVSQDDRR PEGQSRIPVK
2760 2770 2780 2790 2800
KMQESKLPVY QVFAREKQPQ AIDPSDESVS VQNDLMALKA TDERAQSNEI
2810 2820 2830 2840 2850
VVNDSGSEDV KTQRTEMSSK AMPDYFSEQQ AKDLACHVTS DLATKGPWDK
2860 2870 2880 2890 2900
KVFRTWESSG ATNNKSQKEK LSHVLVHDVR ENHIGHPESK IVDQRNEFMS
2910 2920 2930 2940 2950
VTEREHKLLT NGSLSEIKEM TVKSPSKKVL YREYVVKEGE RPGGPLEPPS
2960 2970 2980 2990 3000
RRSESSAVSH IPVRAMEGRR MLSSDIPDGF CEQSTFPQHE LSQKLPQSSM
3010 3020 3030 3040 3050
SKETVETQHF NSIEDEKVTY SEISKVSKRQ SYVGLCPALD ETETSPTKSP
3060 3070 3080 3090 3100
DSLEFSPGKE SPSSDVFDHS PLDGLERVAP LAQTEGGKDI KTLPVYVSFV
3110 3120 3130 3140 3150
QVGKQYEKEI QQGGVKKIIS QECKTVQETR GTFYTTRQQK QPPSPQGSPE
3160 3170 3180 3190 3200
DDTLEQVSFL DSSGKSPLTP ETPSSEEVSY EFTSKTPDSL IAYIPGKPSP
3210 3220 3230 3240 3250
IPEVSEESEE EELAKSASLK QPTVEEATVE RETPTDVSKD SNQRPKSNRV
3260 3270 3280 3290 3300
AYIEFPPPPP LDADQMEPDK KHHYRPEREV DMIEVSLQDE HDKYQLAEPV
3310 3320 3330 3340 3350
IRVQPPSPVP PGADISDSSD DESIYQPVPV KKYTFKLKEV EEEQKEMTKS
3360 3370 3380 3390 3400
KAPVDKPSNQ KELETNGSGK DHEFGLGLDS PQNETAQNGN NDQSITECSI
3410 3420 3430 3440 3450
ATTAEFSHDT DATEIDSLDG YDLQDEDDGL TESDSKLPGQ TMEIKKDVWN
3460 3470 3480 3490 3500
MEGILKPADR SFSQSKLEVI EEEGRVGPDE DKPPSKSSSS EKTPDKTDQK
3510 3520 3530 3540 3550
SGAQFFTLEG RHPDRSVFPD TYFSYKVDEE FATPFKTVAT KGLDFDPWSN
3560 3570 3580 3590 3600
NRGDDEVFDS KSREDETKPF GLAVEDRSPA TTPDTTPART PTDESTPTSE
3610 3620 3630 3640 3650
PNPFPFHEGK MFEMTRSGAI DMSKRDFVEE RLQFFQIGEH TSEGKSGDQG
3660 3670 3680 3690 3700
EGDKSMVTAT PQPQSGDTSV ETNLERNVEA PPVEANPSSP TSGECQEGAA
3710 3720 3730 3740 3750
SGGSLEKSAA APSASKVDPK LRTPIKMGIS ASTMTMKKEG SGEVTDKLEA
3760 3770 3780 3790 3800
VMTSCQGLEN ETITMIANTA NSHMGTRPQE KHDFQKDNFN NNNNLDSSTM
3810 3820 3830 3840 3850
QTDNITSNVV LTEHSAPTCT TEKANPVKIS SGKKTGVLQG HCVRDKQKVL
3860 3870 3880 3890 3900
GEQQKTKESI GIRRKSKLPI KATSPKDICP PSHMPNMKVS KTKQVSQSEK
3910 3920 3930 3940 3950
TKTLIASSCV DVKSRIPVKD THRDNAVRKA CATPKQGQPE KGKAKQLPSK
3960 3970 3980 3990 4000
LPVKVRSTCV TSTTSTSTST STTPTATPTA TTPTATTATT PTATVKVRKS
4010 4020 4030 4040 4050
QLKEVCKHSI EYFKGISGET LKLVDRLSEE DKKMQSELSD EEDSTSRNTS
4060 4070 4080 4090 4100
LSETSRGGQP SVTTKSARDK KTEAAPLKSK SEKAGSEKRS SRRTGPQSPC
4110 4120 4130 4140 4150
ERTDIRMAIV ADHLGLSWTE LARELNFSVD EINQIRVENP NSLISQSFML
4160 4170 4180 4190 4200
LKKWVTRDGK NATTDALTSV LTKINRIDIV TLLEGPIFDY GNISGTRSFA
4210 4220 4230 4240 4250
DENNVFHDPV DGWQNETSSG NLESSAQARR ITGGLLERLD DSPDQCRDSI
4260 4270 4280 4290 4300
TSYLKGEPGK FEANGSHAEI TPEAKTKSYF PESQNDVGKQ SAKETLKPKI
4310 4320 4330 4340 4350
HGSGRVEEPA SSLAAYQKAL EETNKFVIEE PKPCVPVSMK KMSRTPADGK
4360 4370 4380 4390 4400
PRLNLHEEEG SSGSEQKVKS PGAALTRMTA CCYKQGEGYK VKTTKKEIRH

VEKKSHS
Length:4,407
Mass (Da):482,858
Last modified:September 12, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3322F4FA419100B4
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_021555178.1, XM_021699503.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_021555178.1, XM_021699503.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
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Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd00204 ANK, 7 hits
cd08803 Death_ank3, 1 hit
Gene3Di1.25.40.20, 3 hits
InterProiView protein in InterPro
IPR037971 Ank3_Death
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR040745 Ankyrin_UPA
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR000906 ZU5_dom
PfamiView protein in Pfam
PF00023 Ank, 2 hits
PF12796 Ank_2, 6 hits
PF13606 Ank_3, 1 hit
PF00531 Death, 1 hit
PF17809 UPA_2, 1 hit
PF00791 ZU5, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 22 hits
SM00005 DEATH, 1 hit
SM00218 ZU5, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF48403 SSF48403, 2 hits
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 21 hits
PS50017 DEATH_DOMAIN, 1 hit
PS51145 ZU5, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2Y9HTU8_NEOSC
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2Y9HTU8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 12, 2018
Last sequence update: September 12, 2018
Last modified: June 5, 2019
This is version 7 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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