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Entry version 14 (10 Feb 2021)
Sequence version 1 (12 Sep 2018)
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Protein
Submitted name:

LOW QUALITY PROTEIN: breast cancer type 2 susceptibility protein

Gene

BRCA2

Organism
Physeter macrocephalus (Sperm whale) (Physeter catodon)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDNA-bindingARBA annotation
Biological processDNA damage, DNA recombinationARBA annotation, DNA repairARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
LOW QUALITY PROTEIN: breast cancer type 2 susceptibility proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:BRCA2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPhyseter macrocephalus (Sperm whale) (Physeter catodon)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9755 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaArtiodactylaWhippomorphaCetaceaOdontocetiPhyseteridaePhyseter
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000248484 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A2Y9EMN5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati997 – 1031BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1212 – 1246BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1417 – 1451BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1517 – 1551BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1662 – 1696BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati1983 – 2017BRCA2PROSITE-ProRule annotationAdd BLAST35
Repeati2053 – 2087BRCA2PROSITE-ProRule annotationAdd BLAST35
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini2827 – 2868TowerInterPro annotationAdd BLAST42

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni2372 – 2398DisorderedSequence analysisAdd BLAST27
Regioni2426 – 2456DisorderedSequence analysisAdd BLAST31
Regioni3359 – 3425DisorderedSequence analysisAdd BLAST67

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili2855 – 2875Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi2426 – 2455PolyampholyteSequence analysisAdd BLAST30
Compositional biasi3387 – 3412PolarSequence analysisAdd BLAST26

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd04493, BRCA2DBD_OB1, 1 hit
cd04495, BRCA2DBD_OB3, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015525, BRCA2
IPR015252, BRCA2_hlx
IPR036315, BRCA2_hlx_sf
IPR015187, BRCA2_OB_1
IPR015188, BRCA2_OB_3
IPR002093, BRCA2_repeat
IPR012340, NA-bd_OB-fold
IPR015205, Tower_dom

The PANTHER Classification System

More...
PANTHERi
PTHR11289, PTHR11289, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09169, BRCA-2_helical, 1 hit
PF09103, BRCA-2_OB1, 1 hit
PF09104, BRCA-2_OB3, 1 hit
PF00634, BRCA2, 7 hits
PF09121, Tower, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF002397, BRCA2, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01341, Tower, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50249, SSF50249, 3 hits
SSF81872, SSF81872, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50138, BRCA2_REPEAT, 7 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2Y9EMN5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPIGCKERPT FFEIFKTRCN KADLGPISLN WFEELSSEAP PYNSEPSEES
60 70 80 90 100
DYKISSYETN PFKTPQRKPY HQLASTPIIF KERGLTLPLY QSPLKELDKF
110 120 130 140 150
RLDSGKDIAS GKHKSCCTTK AKMNQVNDVT SPPPNSSLSE SPVVLRCTHV
160 170 180 190 200
TPQREKSVIC GSLFHTPKLM KGQTPKRISE SLGAEVDPDM SWSSSLATPP
210 220 230 240 250
TLSSTVLIVR DEEASATVFP NDSTAISKSY SSNHDESLKK NITFIPSGPD
260 270 280 290 300
SENKNQTEAK THGLEKMLED SFGKVNSCKD HFEKSMPNVL EDEVCETVAD
310 320 330 340 350
ISEEDSFPVC VSKYKTRNLQ KIKTGKTRKN IFNETKTDEY EEVKIQMTEN
360 370 380 390 400
KHSFVSEMEP NDSDPLDSNV INQKPLGNGT DKISREIVPS SVSEWSQLTL
410 420 430 440 450
SGLNGSQMEK TSLLYISSCD QNNSEEDIIG TEKERTNFIT LENSLLHISS
460 470 480 490 500
ISKTVKILNE ETVVKKRDEG QCLESHEDST VVGKQALSDS SLIASPLQGI
510 520 530 540 550
KKSVFRIKES PEKTFRADFS SNMTDANFKK EPEASKSGLE VQTVCSQKED
560 570 580 590 600
SLHTSSVDDG SWPATTKHSS VALKNAGLIA SLKKKTKKFI YAICDETSYQ
610 620 630 640 650
GLKMQKDQES ELTNSSVQFE AKPLEAPHTF INVDSGLLHS SVKKNCLQND
660 670 680 690 700
SEEPALSVTS SLGTIMRKCS NNESSSNNNK TISQDLDYKE AKINKEKLQS
710 720 730 740 750
FITTETGYVS CLQEKHCEDD PKSQRVSDVK EKVLPAVFHP ALPHSEECSD
760 770 780 790 800
ILFQSQESFL HGHGSKDLLS NPVVISRGKE SYRMSEKIKS ENCEAGFELT
810 820 830 840 850
KSISMEKNQE TCVVNENSKN AELLSPEKYI TEASPSMKVQ FNQNTNLTVI
860 870 880 890 900
QKDQEETTLI SKITVTPNSE ELFPDKENNF VIQTTTERNI PVLGNIKEVH
910 920 930 940 950
EADLSCLREP VPKNSAIVAC TDIDDGQAAK VSITKDFGSS DVVRDLAEKN
960 970 980 990 1000
RNSVKQPPKM TLGQDSKSYV SLDIDMKSNR NNDCMDKWAG LSDSISSHNF
1010 1020 1030 1040 1050
GSGFRTASNK EIKLSEHNIK KSKMLFKDIE EHYPTSLACV EIVNTVSLEN
1060 1070 1080 1090 1100
QKKGSRPREL DSQSVNTVSG YVQSSAVVSD SGNSHTTPPV LSLKRDFNSN
1110 1120 1130 1140 1150
HNLTPSQKAE ITELSTILEE SGSQFEFTQF RKPSHMLQSN PFEMPENQIT
1160 1170 1180 1190 1200
VLNTISEECK DVDLHLTINA PSLSQVGSSK KCKGIVGDKQ KLACLSTTNC
1210 1220 1230 1240 1250
NKSASGYLTD KNEVEFRGFY SARGTKLNVS SEALQKAMKL FGDIENVSEE
1260 1270 1280 1290 1300
TPAEVDPGSF SSSQCNDSDA SMFKVENYSN DKNLSEKNNE CQLILQNNIE
1310 1320 1330 1340 1350
MTTGIFVKEY TEDYRRNTEN DDNCTGFVCN LESDGNASNK NDTVYIHKDE
1360 1370 1380 1390 1400
NGLPCIDQQN IHPKLSSQFM KEGYVQIKGL SDLTCLEVVK AEETFNVNMS
1410 1420 1430 1440 1450
NKKESTANKM RQNKKDFDVF DLSFQTASGK NIRVSKESLN KVVNFFDEKS
1460 1470 1480 1490 1500
AEELNNFSDS SNSELLSGVN INKIDISSHE ETDMVKNKIL KGGDPVGIKN
1510 1520 1530 1540 1550
QVLTLQQRPE CEIKKITEPT MLGFHTASGK KVKIAKESLD KVKNLFDEKK
1560 1570 1580 1590 1600
QDNSEITNFS HHGAKMLKDR EVCKEGLELA CETVEITAPK HEEMQYSLEK
1610 1620 1630 1640 1650
KKLVSKETGM PPRLLSDHLY RQTENLKISN SISLKVKVHE NIEETRKSPI
1660 1670 1680 1690 1700
TCYTDQSTCS AIENSALAFY TGRGRKISVS QASLFEAKKW IREGELNNQL
1710 1720 1730 1740 1750
EKINSAKIIC LKEYPGDCVG NPSCGNSSNS IITENDKNLS EKQDSTSLSN
1760 1770 1780 1790 1800
SMSNNYSYHS DFSHSNELFN KSEYLSKNKS HNSDIESVVR NVKDRKNTSF
1810 1820 1830 1840 1850
SEVISTVREA NINPQAVDKD SCVQKLVTNS SPCKNKNTAV EVAISDSNNF
1860 1870 1880 1890 1900
ETEQPAFSLA SDKIAFVSHE TKVRERFTDN CSNVTKQNTE SESGTGRTKI
1910 1920 1930 1940 1950
VTGSHKALGD SEDIIFPNSP DSEEHSMHSH EVFPNIQSEH ILQHDQSISG
1960 1970 1980 1990 2000
LEKVSETPLC HINLKTSDKC KFNMGKCPKS VSSINVCGIF STASGKSVQV
2010 2020 2030 2040 2050
SDAALQKARQ VFSKTEDSAK HLFSKVSFKS NEEHSNKFAR EENTVMHTPQ
2060 2070 2080 2090 2100
NLLSSAFSGF STASGKHVLV SESAFCKVTG MFEEFDLIGT ECSLQHSSPS
2110 2120 2130 2140 2150
RQDVSKILPL SCIDKRTSEH SVSSKMGKAY NKEFKLSNNY NIESGSSENH
2160 2170 2180 2190 2200
AIKASPYLSQ FKQDKQQLMS GTNVSHVENI CLLGKEQALP KNIKMEIGKT
2210 2220 2230 2240 2250
ETFPDLPMKT NTEVCSPNSK DPENYFETEA VEIAKAFMED DELTDSELLS
2260 2270 2280 2290 2300
HAKHSIFTCQ KNEAVLINSG IGKRGGDVLV TVGEPPIKRN LLNEFDRIIE
2310 2320 2330 2340 2350
NQEKYLKASK STPDGTMKDR RLFMHHISLE PVTCGPSCTS TERRETQNPN
2360 2370 2380 2390 2400
FTASGQEFLS KSHFSEHLTL EKSSSTLSVS GQPLCKVPAP RNEKRRHSVT
2410 2420 2430 2440 2450
TGKPMKVFVP PFKTKSHVHR DEQCVNRNTN FEENKQKQKN IDEHGSGDRE
2460 2470 2480 2490 2500
NNVNDSEIHQ TTTVLFTKGE EEPLDLIANL QTARDIQDMR IKMKQRQRIF
2510 2520 2530 2540 2550
PQPGSLYLAK TSTMPRISLK VAVEGRVPTA CSHKQLYRYG VSKHCVKINS
2560 2570 2580 2590 2600
KNAESFQFHT QDYFGKESLW AGKGIQLADG GWLIPSNDGK AGKEEFYRAL
2610 2620 2630 2640 2650
CDTPGVDPKL ISRVWVYNHY RWIIWKLAAM EFAFPKEFAN RCLSPERVLL
2660 2670 2680 2690 2700
QLKYRYDMEI DRSRRSAIKK IMERDDTAAK TLVLCVSEII SLSTNVSETS
2710 2720 2730 2740 2750
SSKTNSMDTT KVGVVELTDG WYAIKAQVDP PLLALLKNSR LTVGQKIIIH
2760 2770 2780 2790 2800
GAELVGSPDA CTPLEAPESL MLKISANSTR PACWYAKLGF FSNPRPFPLP
2810 2820 2830 2840 2850
LSSLFSDGGN VGCVDIIIQR AYPIQWMEKT SSGLYIFRNE REEEKEATKY
2860 2870 2880 2890 2900
AEAQQKKLEA LFTKIQAEFE EHEENITERC IPSRALTRQQ VRALQDGAEL
2910 2920 2930 2940 2950
YEAVKDSPDP SYLEGYFSEE QLRALNNHRR TLNDKKQAQI HVELRKAMES
2960 2970 2980 2990 3000
AEQREQILPR DVTPVWKLRI MSCKRKEKDS VVLSIWRPSS DLYSLLTEGK
3010 3020 3030 3040 3050
RYRIYHLAAS KSKSKSERAN IQLTATKKTQ YQQLPASDEI LLQVYQPREP
3060 3070 3080 3090 3100
LHFNKLLDPD FQPPCSEVDL IGFVVSVVKK IGLAPLVYLS DECHNLLAIK
3110 3120 3130 3140 3150
FWIDLNADII KPHMLIAASN LQWRPESKSG IPTLFAGDFS MFSASPKEGH
3160 3170 3180 3190 3200
FQEMFHKMKN TIENMDIFCN DAENKLIRIL NTNNPKWSTP TKDYTSAPHT
3210 3220 3230 3240 3250
AQTVLDTGNK FLVSSPSSEM NYQSPLSLCK LKGKSVSTPA AAQMTSKSCC
3260 3270 3280 3290 3300
KGEKETDDPK NCKKRRALDF LSRLPVPPPV SPICTFVSPA AQKAFQPPRS
3310 3320 3330 3340 3350
CGTKYETPMK KKELNSPQMT PLKKFNDISL LEGDSIADEE LALINTQALL
3360 3370 3380 3390 3400
SGSAGENQLT SISESTRTAP TSPKDHLGLK RPYTASVIKE QGNSPARTEE
3410 3420
QKTNMQDTST IKKTSKRLQR RQKPK
Length:3,425
Mass (Da):382,982
Last modified:September 12, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3733B83940EA5A9A
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_007105518.2, XM_007105456.2

Genome annotation databases

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pcad:102995983

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_007105518.2, XM_007105456.2

3D structure databases

SMRiA0A2Y9EMN5
ModBaseiSearch...

Genome annotation databases

KEGGipcad:102995983

Family and domain databases

CDDicd04493, BRCA2DBD_OB1, 1 hit
cd04495, BRCA2DBD_OB3, 1 hit
InterProiView protein in InterPro
IPR015525, BRCA2
IPR015252, BRCA2_hlx
IPR036315, BRCA2_hlx_sf
IPR015187, BRCA2_OB_1
IPR015188, BRCA2_OB_3
IPR002093, BRCA2_repeat
IPR012340, NA-bd_OB-fold
IPR015205, Tower_dom
PANTHERiPTHR11289, PTHR11289, 1 hit
PfamiView protein in Pfam
PF09169, BRCA-2_helical, 1 hit
PF09103, BRCA-2_OB1, 1 hit
PF09104, BRCA-2_OB3, 1 hit
PF00634, BRCA2, 7 hits
PF09121, Tower, 1 hit
PIRSFiPIRSF002397, BRCA2, 1 hit
SMARTiView protein in SMART
SM01341, Tower, 1 hit
SUPFAMiSSF50249, SSF50249, 3 hits
SSF81872, SSF81872, 1 hit
PROSITEiView protein in PROSITE
PS50138, BRCA2_REPEAT, 7 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2Y9EMN5_PHYMC
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2Y9EMN5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 12, 2018
Last sequence update: September 12, 2018
Last modified: February 10, 2021
This is version 14 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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Main funding by: National Institutes of Health

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