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Protein
Submitted name:

G-protein coupled receptor 126

Gene

GPR126

Organism
Leptonychotes weddellii (Weddell seal)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Names & Taxonomyi

Protein namesi
Submitted name:
G-protein coupled receptor 126Imported
Gene namesi
Name:GPR126Imported
OrganismiLeptonychotes weddellii (Weddell seal)Imported
Taxonomic identifieri9713 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaPhocidaeLeptonychotes
Proteomesi
  • UP000245341 Componenti: Genome assembly

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei864 – 887HelicalSequence analysisAdd BLAST24
Transmembranei899 – 919HelicalSequence analysisAdd BLAST21
Transmembranei931 – 956HelicalSequence analysisAdd BLAST26
Transmembranei968 – 989HelicalSequence analysisAdd BLAST22
Transmembranei1017 – 1047HelicalSequence analysisAdd BLAST31
Transmembranei1068 – 1087HelicalSequence analysisAdd BLAST20
Transmembranei1093 – 1115HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi93 ↔ 110PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini40 – 148CUBInterPro annotationAdd BLAST109
Domaini798 – 850GPSInterPro annotationAdd BLAST53
Domaini862 – 1116G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST255

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Family and domain databases

CDDicd00041 CUB, 1 hit
Gene3Di2.60.120.290, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000859 CUB_dom
IPR017981 GPCR_2-like
IPR000832 GPCR_2_secretin-like
IPR017983 GPCR_2_secretin-like_CS
IPR000203 GPS
IPR001759 Pentraxin-related
IPR035914 Sperma_CUB_dom_sf
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF00431 CUB, 1 hit
PF01825 GPS, 1 hit
PF00354 Pentaxin, 1 hit
PRINTSiPR00249 GPCRSECRETIN
SMARTiView protein in SMART
SM00042 CUB, 1 hit
SM00303 GPS, 1 hit
SM00159 PTX, 1 hit
SUPFAMiSSF49854 SSF49854, 1 hit
SSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS01180 CUB, 1 hit
PS00650 G_PROTEIN_RECEP_F2_2, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
PS50221 GPS, 1 hit
PS51828 PTX_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2U3XCI1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFHSDQMWNC HWKWKPSSLL FLLALCIVYV PLSVWGCANC RVVLSSPSGT
60 70 80 90 100
FTSPCYPNDY PNSQACMWTL RAPTGYIIQI TFNDFDIEEA PNCIYDSLSL
110 120 130 140 150
DNGESQTKFC GATAKGLSFN SSASEMHVSF SSDFSIQKKG FNASYIRVAV
160 170 180 190 200
SLRNQKVILP QTLDSYQVSV AKSVSIPDLS AFTLCFEATK IGKEDHEWIA
210 220 230 240 250
FSYSNTSFTQ LLSFGKAKNG YFISISGSKC FLNSVLPVKD KEDIFTESFE
260 270 280 290 300
QLCIIWNNSL GSVGVNFKKN YEAVPCDSTI SKVIPGNGKL LLGSSHNEIA
310 320 330 340 350
SLKGDIYNFR LWNFTMHSKV LSNLSCHVKG NVVDWQNDFW NIPTLALKAE
360 370 380 390 400
SNLSCGSYLI PLPAAELANC ADLGTLCQAT VDSPSTPPTV TTNMPVTNRI
410 420 430 440 450
DKQWNDGIVY RISIVIQNIL RHPEVKVQSK VAEWLNSTFQ NWNYTVYVVN
460 470 480 490 500
ISFHQSTGED KIKVRRSIVN DQRLVIWALL VYNATNNPNL EGKDIQQKLL
510 520 530 540 550
KNNESLDEGL RLYAVSVKQL GKCLFLYDPK GYHWPLIPPS VYNFPCPGKQ
560 570 580 590 600
GFYASRTCYR DPANTSVAYW GPPDLSNCSR EVNEVANQIL NLTSDGQTLS
610 620 630 640 650
SANITSIVEQ VKRIVNKEEN IDITLGSTLM NIFSNILTSP DSDLLESSSE
660 670 680 690 700
ALKTIDELAF KIDLSSTSHV NITTQNLALG VSSLSPGTNE ISNFSIGLPS
710 720 730 740 750
NNESYFQMDF ESGQMDPLAS VILPPNLLED LSQEDSVLVK RAQFTFFNKT
760 770 780 790 800
GLFQDVETKK GTLVSYVMAC SIGNITIQGL KDPVRIKIKH MRNQAVPHPI
810 820 830 840 850
CAFWDLNKNE GSGFWNTSGC VAHRDSDESE TVCLCNHLTH FGVLMDLQGT
860 870 880 890 900
ASQIDARNTK VLTFITYIGC GISAIFSAAT LLTYVAFEKL RRDYPSKILM
910 920 930 940 950
NLSTALLFLN LLFLLDGWIT SFHVEGLCTA VAVLLHFFLL ATFTWMGLEA
960 970 980 990 1000
IHMYIALVKV FNTYIRRYIL KFCIIGWGLP ALVVSIVLAS RSQNEVYGKE
1010 1020 1030 1040 1050
GYGKEQGDEF CWIQDPVVFY VTCAGYFGVM FFLNVAMFIV VMVQICGRNG
1060 1070 1080 1090 1100
KRSNRTLREE VLRNLRSVVS LTFLLGMTWG FAFFAWGPLN VPFMYLFSIF
1110 1120 1130 1140 1150
NSLQGLFIFI FHCAMKENVQ KQWRRHLCCG RFRLADNSDW SKTATNIIKK
1160 1170 1180 1190 1200
SSDNLGKSLS SSSIGSNSTY LTSKSKSSST TYFKRNSHTD NASMDKSSTK
1210 1220 1230 1240
LTHADGEQTS IIPVHQVIDK VKGYYNAHSD NFYKNIIMSD TFSHSTKF
Length:1,248
Mass (Da):139,651
Last modified:July 18, 2018 - v1
Checksum:iF0A0BAE73FDFBDAF
GO

Sequence databases

RefSeqiXP_006729161.1, XM_006729098.1

Genome annotation databases

GeneIDi102733430

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_006729161.1, XM_006729098.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi102733430

Family and domain databases

CDDicd00041 CUB, 1 hit
Gene3Di2.60.120.290, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000859 CUB_dom
IPR017981 GPCR_2-like
IPR000832 GPCR_2_secretin-like
IPR017983 GPCR_2_secretin-like_CS
IPR000203 GPS
IPR001759 Pentraxin-related
IPR035914 Sperma_CUB_dom_sf
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF00431 CUB, 1 hit
PF01825 GPS, 1 hit
PF00354 Pentaxin, 1 hit
PRINTSiPR00249 GPCRSECRETIN
SMARTiView protein in SMART
SM00042 CUB, 1 hit
SM00303 GPS, 1 hit
SM00159 PTX, 1 hit
SUPFAMiSSF49854 SSF49854, 1 hit
SSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS01180 CUB, 1 hit
PS00650 G_PROTEIN_RECEP_F2_2, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
PS50221 GPS, 1 hit
PS51828 PTX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2U3XCI1_LEPWE
AccessioniPrimary (citable) accession number: A0A2U3XCI1
Entry historyiIntegrated into UniProtKB/TrEMBL: July 18, 2018
Last sequence update: July 18, 2018
Last modified: November 7, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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