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UniProtKB - A0A2U3VXZ3 (A0A2U3VXZ3_ODORO)

Entry version 9 (12 Aug 2020)
Sequence version 1 (18 Jul 2018)
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Protein
Submitted name:

zinc finger protein 106 isoform X1

Gene

ZNF106

Organism
Odobenus rosmarus divergens (Pacific walrus)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
zinc finger protein 106 isoform X1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF106Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOdobenus rosmarus divergens (Pacific walrus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9708 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Carnivora › Caniformia › Odobenidae › Odobenus ›
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000245340 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1561 – 1849WD_REPEATS_REGIONInterPro annotationAdd BLAST289
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1601 – 1645WDPROSITE-ProRule annotationAdd BLAST45

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni86 – 195DisorderedSequence analysisAdd BLAST110
Regioni428 – 465DisorderedSequence analysisAdd BLAST38
Regioni501 – 527DisorderedSequence analysisAdd BLAST27
Regioni962 – 1088DisorderedSequence analysisAdd BLAST127
Regioni1157 – 1188DisorderedSequence analysisAdd BLAST32
Regioni1223 – 1260DisorderedSequence analysisAdd BLAST38
Regioni1309 – 1517DisorderedSequence analysisAdd BLAST209
Regioni1536 – 1561DisorderedSequence analysisAdd BLAST26

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi110 – 127PolyampholyteSequence analysisAdd BLAST18
Compositional biasi138 – 154PolyampholyteSequence analysisAdd BLAST17
Compositional biasi167 – 183PolyampholyteSequence analysisAdd BLAST17
Compositional biasi428 – 453PolarSequence analysisAdd BLAST26
Compositional biasi506 – 526PolarSequence analysisAdd BLAST21
Compositional biasi995 – 1050PolarSequence analysisAdd BLAST56
Compositional biasi1223 – 1242PolarSequence analysisAdd BLAST20
Compositional biasi1336 – 1350PolarSequence analysisAdd BLAST15
Compositional biasi1425 – 1440PolarSequence analysisAdd BLAST16
Compositional biasi1441 – 1455PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1474 – 1488PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1489 – 1517PolarSequence analysisAdd BLAST29

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

WD repeatPROSITE-ProRule annotationARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		2.130.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR018391, PQQ_beta_propeller_repeat
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
IPR042622, Znf106
IPR013087, Znf_C2H2_type

The PANTHER Classification System

More...PANTHERi		PTHR14435, PTHR14435, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00400, WD40, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00564, PQQ, 4 hits
SM00320, WD40, 6 hits
SM00355, ZnF_C2H2, 4 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF50978, SSF50978, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50082, WD_REPEATS_2, 1 hit
PS50294, WD_REPEATS_REGION, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A2U3VXZ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQQTFVKGVK LSASDLVTMV RERKCILCHI VYSSKKEMDE HMRSMLHHRE 
        60         70         80         90        100
LENLKGRDSS HECRVCGVTE VGLSAYAKHI SSQFHKDNVD AQEREDDGKG 
       110        120        130        140        150
EEEEEDYFDK ELVQLIKQRK EQSRQEEPSN SSQEISSDDR RPQWRREDRN 
       160        170        180        190        200
PYQDREGYSQ PAWHHRGPPQ RDWKWEKDGF NNNRKNNFPH SLRNNGGPRG 
       210        220        230        240        250
CSGWHKGVAG GASTWFHNHS NSGGGWHSKS GAVDWNPNGT GRNSSWHSEG 
       260        270        280        290        300
TGGFSSWHMN SSNGNWKSSV RSTNSWNYSG PGDKFQPGRN RNSNCQMDDL 
       310        320        330        340        350
TMLWNKKSKS NKYNQERYSW QRQESDKVGT AATYRGPSEG FTADKFPSEG 
       360        370        380        390        400
LLSFSFEQLE SKTTKQTDPI ASKMGGKNGS VARDKLHRWT PYPPQKTLDL 
       410        420        430        440        450
QSGMKEVTGN KSEIIDKPFF DFSLTTAGTP EPQIDETNHS PTLKTQKETH 
       460        470        480        490        500
GGSLTHKAPS DCPASYEAVR DCPVTEKHEQ ELHLSKMPCL KSALLPIPVT 
       510        520        530        540        550
KSVPQKPDLK NPSKNTKTNS FFPGEHSNPL NKPAMEDSHG SHVTKLRSSC 
       560        570        580        590        600
SHVLKGNKST FGTQREPDEN FSDTLQKAKE VLQCHESLQN PLLGTSKRTR 
       610        620        630        640        650
NFAKASRNVE ESEKGSLKIE FQVHTLEDES DGELSDMEKC GSKIGTLGSA 
       660        670        680        690        700
TTEMLSCSTH LADEKEGDDQ NLKTCRKLST NACNSTVHQK EPELQMTSAA 
       710        720        730        740        750
SPPSGLLLDL KTSLEDAQVD DPVKSHVSYE TEGFESASLD AELQKNDLGQ 
       760        770        780        790        800
SSGPLLPELS KLGFPASLQR DLTRHISLKS KTGAHLPEPN LNSARRIRNI 
       810        820        830        840        850
SGHRKGETEK ESGLKPTLRQ ILNASRRNVN WEQVIQQVTK KKQELGKGLP 
       860        870        880        890        900
RFGIEMVPLV QNEQEVLDLD GEPDLSNLEG FQWEGISISS SPGLARKRSL 
       910        920        930        940        950
SESSVIMDRA PSVYSFFSEE GTGKENEPQQ IFSPSNSLRA AQSQTTTLGL 
       960        970        980        990       1000
KQEVTPLAAS LRTGERAENV ASQRRHSAQL SSDRTIPLMH LAKDLNSQEG 
      1010       1020       1030       1040       1050
STPSSENQNT QESNGEGNSL SSNTSSALGI SSLADAATDS SCTSGAEQND 
      1060       1070       1080       1090       1100
SQSVRKKRRA TGDGSSPELP SLERKNKRRK IKGKKERSQV DQLLNISLRE 
      1110       1120       1130       1140       1150
EELSKSLQCM DNNLLQARAA LQTAYVEVQR LLMLKQQITM EMSALRTHRI 
      1160       1170       1180       1190       1200
QILQGLQETY EPSDRPDQVP YSLPRERRNS RSQTSADATL LPTPFFPVVL 
      1210       1220       1230       1240       1250
EPPSSHMSPS STGVPLQVTT SPTFQAHGSV PAPDSSIQIK QEPMSPEHDE 
      1260       1270       1280       1290       1300
SVTAVSQGSA GNVSKELLQA NRENSDSCPV YPVITATLSL SEVTESFHEP 
      1310       1320       1330       1340       1350
SQELKFSMEQ GNTRNRGNAP SSQPADLHEE PVKGNSGSEA CTSSFPRLSF 
      1360       1370       1380       1390       1400
VSETPLERDP HSPADQPEQQ AESTLTSAET RGNKKKKKLR KKKTLRAAHV 
      1410       1420       1430       1440       1450
PENSDTEQDV FTAKPVRKVK TGKSTKGGKV TTSTWEDSRT GPEQESVRDE 
      1460       1470       1480       1490       1500
PDSDSSLEVL EIPNPQLEVV AIDSSESGEE KPDSPSKKDI WNSTEQNSLE 
      1510       1520       1530       1540       1550
TSRSGCDEVS STSEIGTRYK DGIPVSVAET QTVISSIKGS KNSSEISSEP 
      1560       1570       1580       1590       1600
GDDDEPTEGS FEGHQAAVNA IQIFGNLLYT CSADKTVRAY NLVSRKCIGV 
      1610       1620       1630       1640       1650
FEGHTSKVNC LLVTQTSGKN AALYTGSSDH TIRCYNVKTR ECVEQLQLED 
      1660       1670       1680       1690       1700
RVLCLHSRWR ILYAGLANGT VVTFNIKNNK RLEIFECHGP RAVSCLATAQ 
      1710       1720       1730       1740       1750
EGARKLLVVG SYDCTISVRD ARNGLLLRTL EGHSKTILCM KVVNDLVFSG 
      1760       1770       1780       1790       1800
SSDQSVHAHN IHTGELVRIY KGHNHAVTVV NILGKVMVTA CLDKFVRVYE 
      1810       1820       1830       1840       1850
LQSHDRLQVY GGHKDMIMCM TIHKSMIYTG CYDGSIQAVR LNLMQNYRCW 
      1860       1870       1880       1890       1900
WHGCALIFGI VDHLKQHLLT DHTNPNFQTL KCRWKNCDAF FTARKGSKQD 
      1910 
AAGHIERHAE DDSKIDS
Length:1,917
Mass (Da):212,563
Last modified:July 18, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE82AC4FC4F4B72B2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2U3ZFQ2A0A2U3ZFQ2_ODORO
zinc finger protein 106 isoform X2
ZNF106
1,105Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...RefSeqi		XP_004400443.2, XM_004400386.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...GeneIDi		101383764

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		oro:101383764

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_004400443.2, XM_004400386.2

3D structure databases

Database of comparative protein structure models

More...ModBasei		Search...

SWISS-MODEL Interactive Workspace

More...SWISS-MODEL-Workspacei		Submit a new modelling project...

Genome annotation databases

GeneIDi101383764
KEGGioro:101383764

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		64397

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR018391, PQQ_beta_propeller_repeat
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
IPR042622, Znf106
IPR013087, Znf_C2H2_type
PANTHERiPTHR14435, PTHR14435, 1 hit
PfamiView protein in Pfam
PF00400, WD40, 1 hit
SMARTiView protein in SMART
SM00564, PQQ, 4 hits
SM00320, WD40, 6 hits
SM00355, ZnF_C2H2, 4 hits
SUPFAMiSSF50978, SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50082, WD_REPEATS_2, 1 hit
PS50294, WD_REPEATS_REGION, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2U3VXZ3_ODORO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2U3VXZ3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 18, 2018
Last sequence update: July 18, 2018
Last modified: August 12, 2020
This is version 9 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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