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Entry version 9 (12 Aug 2020)
Sequence version 1 (18 Jul 2018)
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Protein
Submitted name:

zinc finger protein 106 isoform X1

Gene

ZNF106

Organism
Odobenus rosmarus divergens (Pacific walrus)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
zinc finger protein 106 isoform X1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:ZNF106Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOdobenus rosmarus divergens (Pacific walrus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9708 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaOdobenidaeOdobenus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000245340 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1561 – 1849WD_REPEATS_REGIONInterPro annotationAdd BLAST289
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati1601 – 1645WDPROSITE-ProRule annotationAdd BLAST45

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni86 – 195DisorderedSequence analysisAdd BLAST110
Regioni428 – 465DisorderedSequence analysisAdd BLAST38
Regioni501 – 527DisorderedSequence analysisAdd BLAST27
Regioni962 – 1088DisorderedSequence analysisAdd BLAST127
Regioni1157 – 1188DisorderedSequence analysisAdd BLAST32
Regioni1223 – 1260DisorderedSequence analysisAdd BLAST38
Regioni1309 – 1517DisorderedSequence analysisAdd BLAST209
Regioni1536 – 1561DisorderedSequence analysisAdd BLAST26

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi110 – 127PolyampholyteSequence analysisAdd BLAST18
Compositional biasi138 – 154PolyampholyteSequence analysisAdd BLAST17
Compositional biasi167 – 183PolyampholyteSequence analysisAdd BLAST17
Compositional biasi428 – 453PolarSequence analysisAdd BLAST26
Compositional biasi506 – 526PolarSequence analysisAdd BLAST21
Compositional biasi995 – 1050PolarSequence analysisAdd BLAST56
Compositional biasi1223 – 1242PolarSequence analysisAdd BLAST20
Compositional biasi1336 – 1350PolarSequence analysisAdd BLAST15
Compositional biasi1425 – 1440PolarSequence analysisAdd BLAST16
Compositional biasi1441 – 1455PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1474 – 1488PolyampholyteSequence analysisAdd BLAST15
Compositional biasi1489 – 1517PolarSequence analysisAdd BLAST29

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

WD repeatPROSITE-ProRule annotationARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.130.10.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018391, PQQ_beta_propeller_repeat
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
IPR042622, Znf106
IPR013087, Znf_C2H2_type

The PANTHER Classification System

More...
PANTHERi
PTHR14435, PTHR14435, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00400, WD40, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00564, PQQ, 4 hits
SM00320, WD40, 6 hits
SM00355, ZnF_C2H2, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50978, SSF50978, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50082, WD_REPEATS_2, 1 hit
PS50294, WD_REPEATS_REGION, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A2U3VXZ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQQTFVKGVK LSASDLVTMV RERKCILCHI VYSSKKEMDE HMRSMLHHRE
60 70 80 90 100
LENLKGRDSS HECRVCGVTE VGLSAYAKHI SSQFHKDNVD AQEREDDGKG
110 120 130 140 150
EEEEEDYFDK ELVQLIKQRK EQSRQEEPSN SSQEISSDDR RPQWRREDRN
160 170 180 190 200
PYQDREGYSQ PAWHHRGPPQ RDWKWEKDGF NNNRKNNFPH SLRNNGGPRG
210 220 230 240 250
CSGWHKGVAG GASTWFHNHS NSGGGWHSKS GAVDWNPNGT GRNSSWHSEG
260 270 280 290 300
TGGFSSWHMN SSNGNWKSSV RSTNSWNYSG PGDKFQPGRN RNSNCQMDDL
310 320 330 340 350
TMLWNKKSKS NKYNQERYSW QRQESDKVGT AATYRGPSEG FTADKFPSEG
360 370 380 390 400
LLSFSFEQLE SKTTKQTDPI ASKMGGKNGS VARDKLHRWT PYPPQKTLDL
410 420 430 440 450
QSGMKEVTGN KSEIIDKPFF DFSLTTAGTP EPQIDETNHS PTLKTQKETH
460 470 480 490 500
GGSLTHKAPS DCPASYEAVR DCPVTEKHEQ ELHLSKMPCL KSALLPIPVT
510 520 530 540 550
KSVPQKPDLK NPSKNTKTNS FFPGEHSNPL NKPAMEDSHG SHVTKLRSSC
560 570 580 590 600
SHVLKGNKST FGTQREPDEN FSDTLQKAKE VLQCHESLQN PLLGTSKRTR
610 620 630 640 650
NFAKASRNVE ESEKGSLKIE FQVHTLEDES DGELSDMEKC GSKIGTLGSA
660 670 680 690 700
TTEMLSCSTH LADEKEGDDQ NLKTCRKLST NACNSTVHQK EPELQMTSAA
710 720 730 740 750
SPPSGLLLDL KTSLEDAQVD DPVKSHVSYE TEGFESASLD AELQKNDLGQ
760 770 780 790 800
SSGPLLPELS KLGFPASLQR DLTRHISLKS KTGAHLPEPN LNSARRIRNI
810 820 830 840 850
SGHRKGETEK ESGLKPTLRQ ILNASRRNVN WEQVIQQVTK KKQELGKGLP
860 870 880 890 900
RFGIEMVPLV QNEQEVLDLD GEPDLSNLEG FQWEGISISS SPGLARKRSL
910 920 930 940 950
SESSVIMDRA PSVYSFFSEE GTGKENEPQQ IFSPSNSLRA AQSQTTTLGL
960 970 980 990 1000
KQEVTPLAAS LRTGERAENV ASQRRHSAQL SSDRTIPLMH LAKDLNSQEG
1010 1020 1030 1040 1050
STPSSENQNT QESNGEGNSL SSNTSSALGI SSLADAATDS SCTSGAEQND
1060 1070 1080 1090 1100
SQSVRKKRRA TGDGSSPELP SLERKNKRRK IKGKKERSQV DQLLNISLRE
1110 1120 1130 1140 1150
EELSKSLQCM DNNLLQARAA LQTAYVEVQR LLMLKQQITM EMSALRTHRI
1160 1170 1180 1190 1200
QILQGLQETY EPSDRPDQVP YSLPRERRNS RSQTSADATL LPTPFFPVVL
1210 1220 1230 1240 1250
EPPSSHMSPS STGVPLQVTT SPTFQAHGSV PAPDSSIQIK QEPMSPEHDE
1260 1270 1280 1290 1300
SVTAVSQGSA GNVSKELLQA NRENSDSCPV YPVITATLSL SEVTESFHEP
1310 1320 1330 1340 1350
SQELKFSMEQ GNTRNRGNAP SSQPADLHEE PVKGNSGSEA CTSSFPRLSF
1360 1370 1380 1390 1400
VSETPLERDP HSPADQPEQQ AESTLTSAET RGNKKKKKLR KKKTLRAAHV
1410 1420 1430 1440 1450
PENSDTEQDV FTAKPVRKVK TGKSTKGGKV TTSTWEDSRT GPEQESVRDE
1460 1470 1480 1490 1500
PDSDSSLEVL EIPNPQLEVV AIDSSESGEE KPDSPSKKDI WNSTEQNSLE
1510 1520 1530 1540 1550
TSRSGCDEVS STSEIGTRYK DGIPVSVAET QTVISSIKGS KNSSEISSEP
1560 1570 1580 1590 1600
GDDDEPTEGS FEGHQAAVNA IQIFGNLLYT CSADKTVRAY NLVSRKCIGV
1610 1620 1630 1640 1650
FEGHTSKVNC LLVTQTSGKN AALYTGSSDH TIRCYNVKTR ECVEQLQLED
1660 1670 1680 1690 1700
RVLCLHSRWR ILYAGLANGT VVTFNIKNNK RLEIFECHGP RAVSCLATAQ
1710 1720 1730 1740 1750
EGARKLLVVG SYDCTISVRD ARNGLLLRTL EGHSKTILCM KVVNDLVFSG
1760 1770 1780 1790 1800
SSDQSVHAHN IHTGELVRIY KGHNHAVTVV NILGKVMVTA CLDKFVRVYE
1810 1820 1830 1840 1850
LQSHDRLQVY GGHKDMIMCM TIHKSMIYTG CYDGSIQAVR LNLMQNYRCW
1860 1870 1880 1890 1900
WHGCALIFGI VDHLKQHLLT DHTNPNFQTL KCRWKNCDAF FTARKGSKQD
1910
AAGHIERHAE DDSKIDS
Length:1,917
Mass (Da):212,563
Last modified:July 18, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE82AC4FC4F4B72B2
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2U3ZFQ2A0A2U3ZFQ2_ODORO
zinc finger protein 106 isoform X2
ZNF106
1,105Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_004400443.2, XM_004400386.2

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
101383764

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
oro:101383764

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_004400443.2, XM_004400386.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

GeneIDi101383764
KEGGioro:101383764

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
64397

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR018391, PQQ_beta_propeller_repeat
IPR015943, WD40/YVTN_repeat-like_dom_sf
IPR001680, WD40_repeat
IPR017986, WD40_repeat_dom
IPR036322, WD40_repeat_dom_sf
IPR042622, Znf106
IPR013087, Znf_C2H2_type
PANTHERiPTHR14435, PTHR14435, 1 hit
PfamiView protein in Pfam
PF00400, WD40, 1 hit
SMARTiView protein in SMART
SM00564, PQQ, 4 hits
SM00320, WD40, 6 hits
SM00355, ZnF_C2H2, 4 hits
SUPFAMiSSF50978, SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50082, WD_REPEATS_2, 1 hit
PS50294, WD_REPEATS_REGION, 1 hit
PS00028, ZINC_FINGER_C2H2_1, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2U3VXZ3_ODORO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2U3VXZ3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 18, 2018
Last sequence update: July 18, 2018
Last modified: August 12, 2020
This is version 9 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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