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Protein
Submitted name:

acetylcholine receptor subunit beta isoform X1

Gene

CHRNB1

Organism
Odobenus rosmarus divergens (Pacific walrus)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channel, Ligand-gated ion channelSAAS annotation, ReceptorSAAS annotationImported
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
acetylcholine receptor subunit beta isoform X1Imported
Gene namesi
Name:CHRNB1Imported
OrganismiOdobenus rosmarus divergens (Pacific walrus)Imported
Taxonomic identifieri9708 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaLaurasiatheriaCarnivoraCaniformiaOdobenidaeOdobenus
Proteomesi
  • UP000245340 Componenti: Genome assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei247 – 271HelicalSequence analysisAdd BLAST25
Transmembranei278 – 296HelicalSequence analysisAdd BLAST19
Transmembranei308 – 333HelicalSequence analysisAdd BLAST26
Transmembranei474 – 496HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, Postsynaptic cell membraneSAAS annotation, Synapse

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 21Sequence analysisAdd BLAST21
ChainiPRO_501547136722 – 505Sequence analysisAdd BLAST484

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 246Neur_chan_LBDInterPro annotationAdd BLAST218
Domaini253 – 491Neur_chan_membInterPro annotationAdd BLAST239

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

KOiK04812

Family and domain databases

Gene3Di2.70.170.10, 1 hit
InterProiView protein in InterPro
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
IPR036719 Neuro-gated_channel_TM_sf
IPR006029 Neurotrans-gated_channel_TM
IPR018000 Neurotransmitter_ion_chnl_CS
IPR002394 Nicotinic_acetylcholine_rcpt
PANTHERiPTHR18945 PTHR18945, 1 hit
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 1 hit
PF02932 Neur_chan_memb, 1 hit
PRINTSiPR00254 NICOTINICR
PR00252 NRIONCHANNEL
SUPFAMiSSF63712 SSF63712, 1 hit
SSF90112 SSF90112, 1 hit
TIGRFAMsiTIGR00860 LIC, 1 hit
PROSITEiView protein in PROSITE
PS00236 NEUROTR_ION_CHANNEL, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A2U3VTA5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTPGPLLLLL LGALGAPLAP GARSTEAEGR LREKLFSGYD SSVRPAREVG
60 70 80 90 100
DRVGVSIGLS LAQLISLNEK DEEMNTKVYL DLEWTDYRLS WDPAEHDGID
110 120 130 140 150
SLRITAGSVW LPDVVLLNNN DGNFDVALDL NVVVSSNGSV RWQPPGLYRS
160 170 180 190 200
SCSIQVTYFP FDWQNCTMVF SSYSYDSSEV SLRTGLGPHK QERREVHIHE
210 220 230 240 250
GTFIENGQWE IIHKPSRLIQ PPADPRGGGE GQRQEVTFYL IIRRKPLFYL
260 270 280 290 300
VNVIAPCILI TLLAIFVFYL PPDAGEKMGL SIFALLTLTV FLLLLADKVP
310 320 330 340 350
ETSLSVPIII KYLMFTMVLV TFSVILSVVV LNLHHRSPHT HQMPVWVRRI
360 370 380 390 400
FIHKLPLYLG LKRPKPERDL MPEPPPVALR DSPGSGWGRG TDEYFIRKPP
410 420 430 440 450
NDFLFPKPNR FQPELTAPDL RRLTDGPTRA VGLPPELREA VSSISYIARQ
460 470 480 490 500
LQEQEDRDAL KEDWQFVAMV VDRLFLWTFI IFTSVGTLVI FLDASYHLPP

ADPFP
Length:505
Mass (Da):56,977
Last modified:July 18, 2018 - v1
Checksum:iE6BCD09A32CBFEBA
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2U3VTB3A0A2U3VTB3_ODORO
acetylcholine receptor subunit beta...
CHRNB1
432Annotation score:

Sequence databases

RefSeqiXP_004398569.1, XM_004398512.1

Genome annotation databases

GeneIDi101367929
KEGGioro:101367929

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_004398569.1, XM_004398512.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi101367929
KEGGioro:101367929

Phylogenomic databases

KOiK04812

Family and domain databases

Gene3Di2.70.170.10, 1 hit
InterProiView protein in InterPro
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
IPR036719 Neuro-gated_channel_TM_sf
IPR006029 Neurotrans-gated_channel_TM
IPR018000 Neurotransmitter_ion_chnl_CS
IPR002394 Nicotinic_acetylcholine_rcpt
PANTHERiPTHR18945 PTHR18945, 1 hit
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 1 hit
PF02932 Neur_chan_memb, 1 hit
PRINTSiPR00254 NICOTINICR
PR00252 NRIONCHANNEL
SUPFAMiSSF63712 SSF63712, 1 hit
SSF90112 SSF90112, 1 hit
TIGRFAMsiTIGR00860 LIC, 1 hit
PROSITEiView protein in PROSITE
PS00236 NEUROTR_ION_CHANNEL, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2U3VTA5_ODORO
AccessioniPrimary (citable) accession number: A0A2U3VTA5
Entry historyiIntegrated into UniProtKB/TrEMBL: July 18, 2018
Last sequence update: July 18, 2018
Last modified: November 7, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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