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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Nitrosospira multiformis
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotationSAAS annotation

Pathwayi: gluconeogenesis

This protein is involved in the pathway gluconeogenesis, which is part of Carbohydrate biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway gluconeogenesis and in Carbohydrate biosynthesis.

Pathwayi: glycolysis

This protein is involved in step 2 of the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose.UniRule annotationSAAS annotation
Proteins known to be involved in the 4 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Glucose-6-phosphate isomerase (pgi), Glucose-6-phosphate isomerase (pgi), Glucose-6-phosphate isomerase (pgi), Glucose-6-phosphate isomerase (pgi)
  3. Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (pfp), Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (pfp), Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (pfp), Pyrophosphate--fructose 6-phosphate 1-phosphotransferase (pfp)
  4. Fructose-bisphosphate aldolase (SAMN05216412_10451), Fructose-bisphosphate aldolase (C8R21_1094), Fructose-bisphosphate aldolase (SAMN05216417_106135), Fructose-bisphosphate aldolase (SAMN05216404_10682), Fructose-1,6-bisphosphate aldolase (C8R20_102257), Fructose-1,6-bisphosphate aldolase (C8R21_101162)
This subpathway is part of the pathway glycolysis, which is itself part of Carbohydrate degradation.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose, the pathway glycolysis and in Carbohydrate degradation.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei389UniRule annotation1
Active sitei509UniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIsomeraseUniRule annotationSAAS annotationImported
Biological processGluconeogenesisUniRule annotationSAAS annotation, GlycolysisUniRule annotationSAAS annotation

Enzyme and pathway databases

UniPathwayi
UPA00109;UER00181

UPA00138

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
ORF Names:C8R21_10177Imported
OrganismiNitrosospira multiformisImported
Taxonomic identifieri1231 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosospira
Proteomesi
  • UP000244152 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotationSAAS annotation

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2T5IHS7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTRPMVTRLT QRPAWKALEA HYQAIKGKHL RQFFADDPKR GERFTAEAAG
60 70 80 90 100
LYLDYSKNRI TDETLHLLVQ LAEECGLRER IEAMFRGDAI NVTEQRAVLH
110 120 130 140 150
IALRTPRNEK ILVDGNDVVP GVHAVLDRMA DFSDRVRSGD WQGHTGKRIR
160 170 180 190 200
NIINIGIGGS DLGPVMAYEA LRHYSLPNLS FRFISNVDGT DFVEATRGLD
210 220 230 240 250
PEETLFIVCS KTFTTTETLT NAHTARRWML RQIKDLDGVR KHFVAVSTNA
260 270 280 290 300
EEVVRFGIDT ANMFEFWDWV GGRYSMDSAI GLSTMIAIGP ENFREMLAGF
310 320 330 340 350
HAMDQHFYSA PFDRNLPVLM GLLSLWYNNF FGAQTLAVLP YEQYLKRFPA
360 370 380 390 400
YLQQLTMESN GKHITLDGSH VDYQTSPIVW GEPGTNGQHS FYQLIHQGTR
410 420 430 440 450
LIPCDFIGFC QTLNPLGDHH DLLMANLFAQ TEALAFGKTE DEVKAEGVPD
460 470 480 490 500
WLCPHRSFEG NRPTNTILAE RLTPHTLGAL VALYEQSVFT QGTIWQIDSF
510 520 530 540
DQWGVELGKV LARRIGQELE DENGEPLKHD SSTNALIQRY NRLKQK
Length:546
Mass (Da):61,963
Last modified:July 18, 2018 - v1
Checksum:i87479FE02DB9DC01
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
QAOK01000001 Genomic DNA Translation: PTQ83383.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
QAOK01000001 Genomic DNA Translation: PTQ83383.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayi
UPA00109;UER00181

UPA00138

Family and domain databases

CDDicd05015 SIS_PGI_1, 1 hit
cd05016 SIS_PGI_2, 1 hit
Gene3Di1.10.1390.10, 1 hit
HAMAPiMF_00473 G6P_isomerase, 1 hit
InterProiView protein in InterPro
IPR001672 G6P_Isomerase
IPR023096 G6P_Isomerase_C
IPR018189 Phosphoglucose_isomerase_CS
IPR035476 SIS_PGI_1
IPR035482 SIS_PGI_2
PANTHERiPTHR11469 PTHR11469, 1 hit
PfamiView protein in Pfam
PF00342 PGI, 1 hit
PRINTSiPR00662 G6PISOMERASE
PROSITEiView protein in PROSITE
PS00765 P_GLUCOSE_ISOMERASE_1, 1 hit
PS00174 P_GLUCOSE_ISOMERASE_2, 1 hit
PS51463 P_GLUCOSE_ISOMERASE_3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2T5IHS7_9PROT
AccessioniPrimary (citable) accession number: A0A2T5IHS7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 18, 2018
Last sequence update: July 18, 2018
Last modified: October 10, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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