Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 23 (02 Jun 2021)
Sequence version 1 (12 Sep 2018)
Previous versions | rss
Add a publicationFeedback
Protein

TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase

Gene

rffT

Organism
Escherichia coli
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis.

UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: enterobacterial common antigen biosynthesis

This protein is involved in the pathway enterobacterial common antigen biosynthesis, which is part of Bacterial outer membrane biogenesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway enterobacterial common antigen biosynthesis and in Bacterial outer membrane biogenesis.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGlycosyltransferaseUniRule annotationImported, Transferase

Enzyme and pathway databases

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00566

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferaseUniRule annotation (EC:2.4.1.325UniRule annotation)
Alternative name(s):
4-alpha-L-fucosyltransferaseUniRule annotation
TDP-Fuc4NAc:lipid II Fuc4NAc transferaseUniRule annotation
Short name:
Fuc4NAc transferaseUniRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:rffTUniRule annotationImported
Synonyms:wecFUniRule annotationImported
ORF Names:B6V57_21315Imported, C4K41_19500Imported, CT146_23275Imported, D1912_14795Imported, D4U49_15690Imported, D7Y10_16710Imported, DNR41_20620Imported, DU333_23025Imported, DW236_19910Imported, E8P32_19515Imported, EA239_19710Imported, EA250_19475Imported, ELT31_21285Imported, EPS94_20780Imported, FQU83_26740Imported, G4280_24915Imported, GFY48_13825Imported, HHG54_004506Imported, HHJ44_16090Imported, HJM41_004035Imported, HJO02_004163Imported, HJS12_003742Imported, HJS53_004029Imported, HmCmsJML146_03430Imported, HPE52_23420Imported, HV055_24485Imported, HV348_24545Imported, MS8345_04219Imported, NCTC10089_04970Imported, NCTC8959_03830Imported, NCTC9434_04901Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coliImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell inner membraneUniRule annotation, Cell membrane, Membrane

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glycosyltransferase 56 family.UniRule annotation

Family and domain databases

HAMAP database of protein families

More...
HAMAPi
MF_01002, WecF_RffT, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR009993, WecF

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07429, Glyco_transf_56, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2S5RMV7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTVLIHVLGS DIPHHNRTVL RFFNDALAAT SGHAREFMVA GKDDGLSDSC
60 70 80 90 100
PALSVQFFPG KKSLAEAVIA KAKANRQQRF FFHGQFNPKL WLALLSGGIK
110 120 130 140 150
PSQFFWHIWG ADLYELSSGL RYKLFYPLRR LAQKRVGCVF ATRGDLSFFA
160 170 180 190 200
KTHPKVRGEL LYFPTRMDPS LNTMANDRQR EGKMTILVGN SGDRSNEHIA
210 220 230 240 250
ALRAVHQQFG DTVKVVVPMG YPPNNEAYIE EVRQAGLELF SEENLQVLSE
260 270 280 290 300
KLEFDAYLTL LRQCDLGYFI FARQQGIGTL CLLIQAGIPC VLNRENPFWQ
310 320 330 340 350
DMTEQHLPVL FTTDDLNEDI VREAQRQLAS VDKNTIAFFS PNYLQGWQRA

LAIAAGEVA
Length:359
Mass (Da):40,499
Last modified:September 12, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB1FD252D620CAB70
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP025401 Genomic DNA Translation: AUG95762.1
CP020545 Genomic DNA Translation: AWG08865.1
AAAFOP010000046 Genomic DNA Translation: EAB7203977.1
BFRA01000106 Genomic DNA Translation: GDA18198.1
DABAIH010000041 Genomic DNA Translation: HAH1052041.1
DABAJK010000020 Genomic DNA Translation: HAH1131618.1
DABEBS010000016 Genomic DNA Translation: HAI3358522.1
DABEHY010000014 Genomic DNA Translation: HAI4144622.1
DABERY010000018 Genomic DNA Translation: HAI5401075.1
DABESK010000014 Genomic DNA Translation: HAI5449488.1
REBD01000018 Genomic DNA Translation: KAA1836067.1
RDVP01000016 Genomic DNA Translation: KAA2141972.1
RVTH01000043 Genomic DNA Translation: MMI29127.1
PENJ01000019 Genomic DNA Translation: PIM21294.1
PSNQ01000018 Genomic DNA Translation: PPE27845.1
CP042246 Genomic DNA Translation: QDX39081.1
CP053231 Genomic DNA Translation: QJS74493.1
CP054345 Genomic DNA Translation: QKM88706.1
CP056190 Genomic DNA Translation: QLR35645.1
CP056876 Genomic DNA Translation: QMA05179.1
CP048867 Genomic DNA Translation: QMX31269.1
QLAC01000015 Genomic DNA Translation: RAH20167.1
QRIX01000013 Genomic DNA Translation: RHG95387.1
QWNV01001677 Genomic DNA Translation: RIC95498.1
RRUU01000013 Genomic DNA Translation: RRK88975.1
SCIX01000018 Genomic DNA Translation: RXB43776.1
UFZD01000005 Genomic DNA Translation: STE13055.1
UGFV01000001 Genomic DNA Translation: STN20008.1
RZAR01000017 Genomic DNA Translation: TFS41529.1
SSTR01000025 Genomic DNA Translation: THG82929.1
CABEEY010000003 Genomic DNA Translation: VTR26491.1

NCBI Reference Sequences

More...
RefSeqi
WP_000217276.1, NZ_WVVR01000021.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AUG95762; AUG95762; MS8345_04219
PIM21294; PIM21294; CT146_23275
PND99654; PND99654; C1I57_07460
PPE27845; PPE27845; C4K41_19500
RAH20167; RAH20167; DNR41_20620
RID05114; RID05114; D1900_08555
STE13055; STE13055; NCTC8959_03830
STN20008; STN20008; NCTC9434_04901

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP025401 Genomic DNA Translation: AUG95762.1
CP020545 Genomic DNA Translation: AWG08865.1
AAAFOP010000046 Genomic DNA Translation: EAB7203977.1
BFRA01000106 Genomic DNA Translation: GDA18198.1
DABAIH010000041 Genomic DNA Translation: HAH1052041.1
DABAJK010000020 Genomic DNA Translation: HAH1131618.1
DABEBS010000016 Genomic DNA Translation: HAI3358522.1
DABEHY010000014 Genomic DNA Translation: HAI4144622.1
DABERY010000018 Genomic DNA Translation: HAI5401075.1
DABESK010000014 Genomic DNA Translation: HAI5449488.1
REBD01000018 Genomic DNA Translation: KAA1836067.1
RDVP01000016 Genomic DNA Translation: KAA2141972.1
RVTH01000043 Genomic DNA Translation: MMI29127.1
PENJ01000019 Genomic DNA Translation: PIM21294.1
PSNQ01000018 Genomic DNA Translation: PPE27845.1
CP042246 Genomic DNA Translation: QDX39081.1
CP053231 Genomic DNA Translation: QJS74493.1
CP054345 Genomic DNA Translation: QKM88706.1
CP056190 Genomic DNA Translation: QLR35645.1
CP056876 Genomic DNA Translation: QMA05179.1
CP048867 Genomic DNA Translation: QMX31269.1
QLAC01000015 Genomic DNA Translation: RAH20167.1
QRIX01000013 Genomic DNA Translation: RHG95387.1
QWNV01001677 Genomic DNA Translation: RIC95498.1
RRUU01000013 Genomic DNA Translation: RRK88975.1
SCIX01000018 Genomic DNA Translation: RXB43776.1
UFZD01000005 Genomic DNA Translation: STE13055.1
UGFV01000001 Genomic DNA Translation: STN20008.1
RZAR01000017 Genomic DNA Translation: TFS41529.1
SSTR01000025 Genomic DNA Translation: THG82929.1
CABEEY010000003 Genomic DNA Translation: VTR26491.1
RefSeqiWP_000217276.1, NZ_WVVR01000021.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsemblBacteriaiAUG95762; AUG95762; MS8345_04219
PIM21294; PIM21294; CT146_23275
PND99654; PND99654; C1I57_07460
PPE27845; PPE27845; C4K41_19500
RAH20167; RAH20167; DNR41_20620
RID05114; RID05114; D1900_08555
STE13055; STE13055; NCTC8959_03830
STN20008; STN20008; NCTC9434_04901

Enzyme and pathway databases

UniPathwayiUPA00566

Family and domain databases

HAMAPiMF_01002, WecF_RffT, 1 hit
InterProiView protein in InterPro
IPR009993, WecF
PfamiView protein in Pfam
PF07429, Glyco_transf_56, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2S5RMV7_ECOLX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2S5RMV7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 12, 2018
Last sequence update: September 12, 2018
Last modified: June 2, 2021
This is version 23 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again