Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 9 (12 Aug 2020)
Sequence version 1 (18 Jul 2018)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Endonuclease

Gene

POL_0

Organism
Schizaphis graminum (Green bug aphid)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
EndonucleaseARBA annotation
Alternative name(s):
Reverse transcriptaseARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:POL_0Imported
ORF Names:g.119438Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizaphis graminum (Green bug aphid)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri13262 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraHemipteraSternorrhynchaAphidomorphaAphidoideaAphididaeAphidiniSchizaphis

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini292 – 476Reverse transcriptaseInterPro annotationAdd BLAST185
Domaini727 – 880MacroInterPro annotationAdd BLAST154
Domaini953 – 1112Integrase catalyticInterPro annotationAdd BLAST160

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni78 – 106DisorderedSequence analysisAdd BLAST29
Regioni692 – 721DisorderedSequence analysisAdd BLAST30

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili595 – 615Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.70.10, 1 hit
3.30.420.10, 1 hit
3.30.70.270, 2 hits
3.40.220.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR001584, Integrase_cat-core
IPR041588, Integrase_H2C2
IPR002589, Macro_dom
IPR043472, Macro_dom-like
IPR021109, Peptidase_aspartic_dom_sf
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
IPR000477, RT_dom
IPR041577, RT_RNaseH_2

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF17921, Integrase_H2C2, 1 hit
PF17919, RT_RNaseH_2, 1 hit
PF00665, rve, 1 hit
PF00078, RVT_1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52949, SSF52949, 1 hit
SSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50994, INTEGRASE, 1 hit
PS51154, MACRO, 1 hit
PS50878, RT_POL, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2S2NNZ3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIREQTEQNL SGITGHTLHS FGTTNLTLCL GKDERTTEFH VAPSSFPVPY
60 70 80 90 100
DGILGKPFII GLQTILNYKT KQLILTDNQN PSNLVNPTER PKTSNSVDNS
110 120 130 140 150
ETQNSTENLQ SKAFKITLQP RSETIISIPT PNLQEEEIYL VPAQTLGESI
160 170 180 190 200
LCSNTVNQVC QKQILIAAVN PTEQSVQLTE EQIKGLKFEN FTEVKVQTIQ
210 220 230 240 250
KVTETVGTKG RLVTLRDSLD TKHLNIEERE SLVSTCEQYS DIFHLEGDPL
260 270 280 290 300
TCTDAVFHEV NTPGTTQPIN ERPYRLPHRH KDEINRQMKQ LEEDNIIAPS
310 320 330 340 350
RSPWNAPLLV VPKKADKDGV VKYRVCVDFR KLNQISVGDA YPLPNIIDIL
360 370 380 390 400
DQLGKSKYYT TLDLAQGYHQ VRMHPEHTEK TAFSTDKGHF EFLRVPFGLK
410 420 430 440 450
GAPATFQRLM NTVLAGLTGL KAFVYLDDII IYALSIADHS EKLKAVFERL
460 470 480 490 500
RTFNLKLQPS KCTFMRKEVN YLGHVITDQG VKPNPQKIKC VIEFPIPTDE
510 520 530 540 550
KKVKSFLGLS GYYRRFVPGY GRIAKPLTTL LKKDVIFKWT DLCQEAFDTL
560 570 580 590 600
KKILTTEPLL QYPDFTRPFN LTCDASNYAI GCVLSQGPIG ADPPIAYASR
610 620 630 640 650
TLNRAESNYN TTEKELCAIV WGVKQFRPYL FGQKFNIVTD HQALNWLFNI
660 670 680 690 700
KDPGSRLTRW RLKLAEYEYE IHFKPGASNT NADALSRINR VVTRSSKSPN
710 720 730 740 750
STESPDNTEP PTSTEHSSST EHLSSYQKFL KEKVAFTPNV VESKGDIFET
760 770 780 790 800
DHSMALAHCV SSDLKMTKGI ALEFRRRFGG LNQLRRLPRT VSDVLSLRLK
810 820 830 840 850
EREIFYLVTK QHFWQKPEPE HLFQSLQKLR TLCEEREIKT LTCPRLGTGL
860 870 880 890 900
DGLQWETVRS MLQYIFRNSQ VTIHVLVPET LSEKDQLQII REFHENPMGG
910 920 930 940 950
HQGTTRTHQR ISQHHNWKGM RKQIKKYIRE CATCQKNKSS NRTAREPMII
960 970 980 990 1000
TTTASRPFEK IYMDIVGPLT KSYNGNVFIL TLQDDLSKFA WAAPMPNHEA
1010 1020 1030 1040 1050
NTVAKFFVTQ FVCLHGLPQS LVTDCGTEFL SKVFKEVCQL LKIKQTSTSP
1060 1070 1080 1090 1100
YHPQSNGSLE RSHRTLAEYL RSFVNKDPQN WDTHVPFAMF CHNSTTHTST
1110 1120 1130 1140 1150
KYQPYQLVYG YPITVPNSFM KNTEPQYNYD DYYFELKRNM QESQAQAKTH
1160 1170 1180 1190 1200
LYDSKQKSKD RYDQKISPLT INIGDKVLIQ EKASKGKLAP KWIGPYTVIE
1210 1220 1230
TNPESPNITI LKKSRPVILH RNLLKKFYEE N
Length:1,231
Mass (Da):140,844
Last modified:July 18, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i602AC930BD1629A1
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GGMR01006290 Transcribed RNA Translation: MBY18909.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GGMR01006290 Transcribed RNA Translation: MBY18909.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di2.40.70.10, 1 hit
3.30.420.10, 1 hit
3.30.70.270, 2 hits
3.40.220.10, 1 hit
InterProiView protein in InterPro
IPR043502, DNA/RNA_pol_sf
IPR001584, Integrase_cat-core
IPR041588, Integrase_H2C2
IPR002589, Macro_dom
IPR043472, Macro_dom-like
IPR021109, Peptidase_aspartic_dom_sf
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR012337, RNaseH-like_sf
IPR036397, RNaseH_sf
IPR000477, RT_dom
IPR041577, RT_RNaseH_2
PfamiView protein in Pfam
PF17921, Integrase_H2C2, 1 hit
PF17919, RT_RNaseH_2, 1 hit
PF00665, rve, 1 hit
PF00078, RVT_1, 1 hit
SUPFAMiSSF52949, SSF52949, 1 hit
SSF53098, SSF53098, 1 hit
SSF56672, SSF56672, 1 hit
PROSITEiView protein in PROSITE
PS50994, INTEGRASE, 1 hit
PS51154, MACRO, 1 hit
PS50878, RT_POL, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2S2NNZ3_SCHGA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2S2NNZ3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 18, 2018
Last sequence update: July 18, 2018
Last modified: August 12, 2020
This is version 9 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Transposable elementARBA annotation
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again