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Entry version 8 (11 Dec 2019)
Sequence version 1 (18 Jul 2018)
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Protein

Integrase catalytic domain-containing protein

Gene

g.92006

Organism
Schizaphis graminum (Green bug aphid)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Integrase catalytic domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:g.92006Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizaphis graminum (Green bug aphid)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri13262 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraHemipteraSternorrhynchaAphidomorphaAphidoideaAphididaeAphidiniSchizaphis

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1457 – 1645Integrase catalyticInterPro annotationAdd BLAST189

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni343 – 374DisorderedSequence analysisAdd BLAST32

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.70.10, 1 hit
3.30.420.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005312 DUF1759
IPR040676 DUF5641
IPR001584 Integrase_cat-core
IPR041588 Integrase_H2C2
IPR008737 Peptidase_asp_put
IPR021109 Peptidase_aspartic_dom_sf
IPR008042 Retrotrans_Pao
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05585 DUF1758, 1 hit
PF03564 DUF1759, 1 hit
PF18701 DUF5641, 1 hit
PF17921 Integrase_H2C2, 1 hit
PF05380 Peptidase_A17, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53098 SSF53098, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50994 INTEGRASE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2S2NNC8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTANTSEVDE SRRVIRMLER STIKREVAVN RLRSVMSLAE RSMKDPEESP
60 70 80 90 100
HLLEAVEDLD NLWSKFEVED EAILDHLLSL ERSSEYSSKL SAEMRELVTF
110 120 130 140 150
CRSVARRYRE SEQSSSNMSV HSGSHVSVMS NKDATIPAVQ QTTVPDITLP
160 170 180 190 200
TVSSSQVSIS RLPEIPLPSF DGDIFQWPSF RDKFSIMVDQ RPTLSNIDKL
210 220 230 240 250
HYLLGCLRGS AMDAIRSIPP SGHTYKLIWS SLESRFDKPR LVAGSVVESL
260 270 280 290 300
LSTPPSTTES LAELNRFMVA FSESVSVLES LAIPNLGDFI LFSLASRCLP
310 320 330 340 350
TSCRTLFETQ VTADYPTVHE LFAFVKSRVS ILERVQDIHV SKPVPPSRSL
360 370 380 390 400
AQPRYDKKGH RRSEKPPQSS FINAAPLPSR SHCICCNNGK HALPSCNRFK
410 420 430 440 450
KWSNDVRSKW ARDHKLCFRC LEDGHWSPQC KSSTVCSHCS RKHHTLVHTA
460 470 480 490 500
EVAGTSRKEE TIPVADQPGS SSVSTSCVGQ LDSHSVLLGT ALVQIRDHVG
510 520 530 540 550
TLHTVRALVD SASQISAITS SCSSRLGLRV SRWTAPVIGL SGAPVPDTLG
560 570 580 590 600
IVNCNVQPRY AEEPVLPIKA WVFSTITANM PRQPLSKVVS EKYRHLALAD
610 620 630 640 650
PSFTTPSAID LLLGADIFAQ VLNGKRVSFG ETFPVAFGSV FGWIIIGPVP
660 670 680 690 700
NSTSQSPHSC PISLLNVSVE SLLDKFWSIE EPAAAPEIFT EEGQCESLFR
710 720 730 740 750
MGCTRSSSGR FTVPLPFRQP VTDELFRGSR TVAIKRFEYL ERRLSADHRL
760 770 780 790 800
RDLYIKFMSE YCSLGHMSPT SNPGSYYIPH HAVYQPSETD PKIRVVFDAS
810 820 830 840 850
ARAFNGVSLN NCLLPGPKLQ RDVVDVLLLF RLLQYVFTTD ICKMYRQILI
860 870 880 890 900
VPEHRKFQRI LWRASPYDQL QEYQLNTVTY GVNCAPYLAI RVLQHIADSD
910 920 930 940 950
CTEFPSVRKA LLFHTYVDDI CVGADSEEAA VELQSALIAV LGRAGLELKK
960 970 980 990 1000
WSSNTHSILN NVPPEDQANG TLPFDEGDGI KVLGLRWSPH DDAFTYGFQN
1010 1020 1030 1040 1050
EKLVATKRGM LSLIARIFDP LGLLSPVVFM AKHFMKLVWR ANVAWDEPLP
1060 1070 1080 1090 1100
PSVSDVWHQF VTELPELRKL CIPRFVHTRS GMRVVLCGFC DASERGYAAV
1110 1120 1130 1140 1150
VYIRSENSSG SSVVSLLGSK TKLAPMAAST IPRLELCGAV LLAKWMSRIK
1160 1170 1180 1190 1200
QTLSVELEIV ETHAWSDSTI VLNWLAVRHV TFKVFVSNRI HQVQSLLPDC
1210 1220 1230 1240 1250
QWHHISSEDN PADCASRGLT PSELVNHVLF WKGPTFLTSS TVEWATRVPS
1260 1270 1280 1290 1300
IEPDQLPEAK VESPTVLLVE TTTEWYSRFS SYVHMIRVVA YVRRFILLCR
1310 1320 1330 1340 1350
RRQQVFECYL TRGELDSASL AIVRFSQLTF FSKLCHELSC SRSISVRSVA
1360 1370 1380 1390 1400
RLRPYIDDSG VIRVGGRLSN AQLSHEQRHP VLLAKSSHLS LLLIRHWHDL
1410 1420 1430 1440 1450
TGHSGPRVIT ALLGRQYWIM SVGTLIRTVI SHCTRCVRLS AANPQPVMAD
1460 1470 1480 1490 1500
LPRSRVTECR PFSRVGIDYA GPLLMKEHRL RKARQYKVYV AVFVCFAVKA
1510 1520 1530 1540 1550
VHLEVVSDLS TDAFIAALNR FVARRGLPTD IYSDCGTNFV GAAAQLKNLI
1560 1570 1580 1590 1600
NHRDNQGQLS ASIQSVWHFN PPGAPHFGGL WEAAVRSAKT LLVRIMGEHT
1610 1620 1630 1640 1650
FTLEEFNTIL CRVEAILNSR PLTPSSTDPN EIDYLSPGHF LIGQPLLAPP
1660 1670 1680 1690 1700
EEDILPNQYS LNNRWKLLNQ CAQAFWRRWR DEYLQTLQTR GRWTTDTPNL
1710 1720 1730 1740 1750
TVDDLVIVKD PHTPPLTWRM ARILDTVPGT DGVVRVVRLR TSTGVLTRPV

VKVVKLPIA
Length:1,759
Mass (Da):197,044
Last modified:July 18, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0376AFAC2B542A52
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GGMR01005823 Transcribed RNA Translation: MBY18442.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GGMR01005823 Transcribed RNA Translation: MBY18442.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di2.40.70.10, 1 hit
3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR005312 DUF1759
IPR040676 DUF5641
IPR001584 Integrase_cat-core
IPR041588 Integrase_H2C2
IPR008737 Peptidase_asp_put
IPR021109 Peptidase_aspartic_dom_sf
IPR008042 Retrotrans_Pao
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PfamiView protein in Pfam
PF05585 DUF1758, 1 hit
PF03564 DUF1759, 1 hit
PF18701 DUF5641, 1 hit
PF17921 Integrase_H2C2, 1 hit
PF05380 Peptidase_A17, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS50994 INTEGRASE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2S2NNC8_SCHGA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2S2NNC8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 18, 2018
Last sequence update: July 18, 2018
Last modified: December 11, 2019
This is version 8 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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