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Entry version 7 (11 Dec 2019)
Sequence version 1 (18 Jul 2018)
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Protein

Integrase catalytic domain-containing protein

Gene

g.112947

Organism
Schizaphis graminum (Green bug aphid)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Integrase catalytic domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:g.112947Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizaphis graminum (Green bug aphid)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri13262 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraParaneopteraHemipteraSternorrhynchaAphidomorphaAphidoideaAphididaeAphidiniSchizaphis

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1425 – 1612Integrase catalyticInterPro annotationAdd BLAST188

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili4 – 24Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.420.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR005312 DUF1759
IPR040676 DUF5641
IPR001584 Integrase_cat-core
IPR041588 Integrase_H2C2
IPR008737 Peptidase_asp_put
IPR008042 Retrotrans_Pao
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05585 DUF1758, 1 hit
PF03564 DUF1759, 1 hit
PF18701 DUF5641, 1 hit
PF17921 Integrase_H2C2, 1 hit
PF05380 Peptidase_A17, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53098 SSF53098, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50994 INTEGRASE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2S2NCY5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGVYEEAKER LRGLQHKVQR VYDAGEALTQ DQSRTAKSKF KIMFASLESV
60 70 80 90 100
ANEFEAQLTI IIRQQCKTAL GTDAVDTEKE RASFEDKYIG CKIFADEHLP
110 120 130 140 150
EAIADASLNQ TFYEQKTHHV SIPVEKLPVP HFKGDQKYYT SFRNQFDVLV
160 170 180 190 200
HNNDMFKPVI KFSYLKAYLG GEPLQLINNL LLSEENYHLA LDILEKRYSN
210 220 230 240 250
RRTIAQDHFD QLWAAREAIL GDSTSIRQLL NTITESVGAL RTQKYAVDQW
260 270 280 290 300
DPILLYLFQK KLDAPLRGQW ELLVDTNDDP TVEDFITFLT KFCKAAGAGN
310 320 330 340 350
FTTSGGEKTL KKPTKSTTLH VAQTVQKRHS NFSERKNSFT CQVCKVKPGH
360 370 380 390 400
LFIECPVFKQ KTPLERHQII KDSNRCYLCF SEHHVENCKN TRVCQECGGR
410 420 430 440 450
HHSWLHLGSR ETSDDDQNDP IRVLFASGKD KPTRSQVLMS TVLVRIRDAQ
460 470 480 490 500
GHYQKARALL DCASESSYMT ESCRNRLGVL RHKCHVAVSG IGGVKAPTVK
510 520 530 540 550
ALAHLEVCPV RQNKPQLTIN AYVVQQITGL TPSKHVVAAE WSHLKGLELA
560 570 580 590 600
DPNFNTPLPV DLLLGADVFP YVIRNGRREN LLTEPVGIET VFGWALMGKT
610 620 630 640 650
GDAKPQMVTT LLTSSIDNVD KALRRFWEIE EVPNVLKTSP TEQQCEEIYC
660 670 680 690 700
TSTTRQADGR YVVHLPFNCQ PPRLGQSRQM ALQRFFRLES RLDKSPELRQ
710 720 730 740 750
QYNAAMQDYL DSGHMSAVPT AIENESCYYT PHQAVIRPES TTTKLRVVYD
760 770 780 790 800
ASATTSNGKS LNDNLLPGRK LQQDLPGIIV RFRLHEVVFT ADIKQMFRQI
810 820 830 840 850
MVTPEHRSYQ RLLYRFNTVE PIQTYEMTTV TFGQRSSPFL AIRTLHQLAI
860 870 880 890 900
DEAQAHIDVQ RVIYNDLYVD DVATGADCIE SALRLQQDLV KVFKQGQFEL
910 920 930 940 950
RKWSSNSPTL LNAIPQEHRQ NQPVAFNEHG PDYTNVLGLK WEPESDTIAY
960 970 980 990 1000
QYQPNPIQYS KRAILSEIAR IYDPVGLLAP VTTHLKKLMK YLWSLGVGWD
1010 1020 1030 1040 1050
DKLPPEAMEA WTTYHEELPL IGQVRVRRQV TTLGSTYELH GFSDSSESAY
1060 1070 1080 1090 1100
AAAVYLLARK PDGTTHSQLV MGKSKVAPEK KLSIPRLELC GSLLLARAIN
1110 1120 1130 1140 1150
YVRTNLTSLQ IDRITAWSDS TVALAWIKTP TSRLKTFVAN RVAQIQHMVP
1160 1170 1180 1190 1200
PDMWRHVPTA QNSADCASRG LTPSELINHS LWWTGPDYLR GPEELWPKMI
1210 1220 1230 1240 1250
DVSSNDDELQ MEQLETKTIT LTTAETLSEC PLLYQSDNWS KILRLTCYWL
1260 1270 1280 1290 1300
RVRKRLQIST KDQPCRGQTS TMSRTHNQPD AEEMDEAMWA LVLWTQRVYF
1310 1320 1330 1340 1350
AEEIVQVQNN RMCSVKIRKL APFLDKKNLL RVGGRLRQSE LPFEEKYPVL
1360 1370 1380 1390 1400
LPKEARLTEV LIDHIHRSNC HPGPQIVQTL AQQFFWILSA RNVIRKRLHR
1410 1420 1430 1440 1450
CVPCFRAHPR APQPFMGNLP RARLEQVKPF NKSGVDFAGP FVVKAAKLRK
1460 1470 1480 1490 1500
LRVTKAYLCI FVCMSTTAVH IELASDLSTP TFIAALDRFL SRRGHCSDIY
1510 1520 1530 1540 1550
SDCGTNFVGT DRYLREVYDI IHEDLYTRHV TNKQIKWHFN PPSAPHMGGL
1560 1570 1580 1590 1600
WEAAVKSAKS LLQRVIQDQI LTYEELNTVL HRVEASLNSR PLGALSSDPS
1610 1620 1630 1640 1650
DFSPLTAGHF LSMGPPATTP VPGTEAPTAQ ISIRQRWALV TQIQQHFWKR
1660 1670 1680 1690 1700
WQREYLNTLQ PRKKWQKPDA NLVEGDLVLI KEHSSPLTWK TARVVAVFPG
1710 1720 1730
DDAVTRVADV KLATGTILRR PVVKLCPLPI IY
Length:1,732
Mass (Da):197,235
Last modified:July 18, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i65A6FDF041EC01B2
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
GGMR01002421 Transcribed RNA Translation: MBY15040.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
GGMR01002421 Transcribed RNA Translation: MBY15040.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Family and domain databases

Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR005312 DUF1759
IPR040676 DUF5641
IPR001584 Integrase_cat-core
IPR041588 Integrase_H2C2
IPR008737 Peptidase_asp_put
IPR008042 Retrotrans_Pao
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PfamiView protein in Pfam
PF05585 DUF1758, 1 hit
PF03564 DUF1759, 1 hit
PF18701 DUF5641, 1 hit
PF17921 Integrase_H2C2, 1 hit
PF05380 Peptidase_A17, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
PROSITEiView protein in PROSITE
PS50994 INTEGRASE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2S2NCY5_SCHGA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2S2NCY5
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 18, 2018
Last sequence update: July 18, 2018
Last modified: December 11, 2019
This is version 7 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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