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Protein
Submitted name:

Uncharacterized protein

Gene

ARHGAP42

Organism
Pan paniscus (Pygmy chimpanzee) (Bonobo)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionGTPase activationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:ARHGAP42Imported
OrganismiPan paniscus (Pygmy chimpanzee) (Bonobo)Imported
Taxonomic identifieri9597 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
Proteomesi
  • UP000240080 Componenti: Chromosome 11

Structurei

3D structure databases

SMRiA0A2R9CIT5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini265 – 374PHInterPro annotationAdd BLAST110
Domaini376 – 572Rho-GAPInterPro annotationAdd BLAST197
Domaini816 – 874SH3InterPro annotationAdd BLAST59

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili87 – 107Sequence analysisAdd BLAST21
Coiled coili225 – 259Sequence analysisAdd BLAST35

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00930000150818
KOiK20651

Family and domain databases

Gene3Di1.10.555.10, 1 hit
1.20.1270.60, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR008936 Rho_GTPase_activation_prot
IPR000198 RhoGAP_dom
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00169 PH, 1 hit
PF00620 RhoGAP, 1 hit
PF14604 SH3_9, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00324 RhoGAP, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF103657 SSF103657, 1 hit
SSF48350 SSF48350, 1 hit
SSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS50238 RHOGAP, 1 hit
PS50002 SH3, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A2R9CIT5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGLPTLEFSD SYLDSPDFRE RLQCHEIELE RTNKFIKELI KDGSLLIGAL
60 70 80 90 100
RNLSMAVQKF SQSLQDFQFE CIGDAETDDE ISIAQSLKEF ARLLIAVEEE
110 120 130 140 150
RRRLIQNAND VLIAPLEKFR KEQIGAAKDG KKKFDKESEK YYSILEKHLN
160 170 180 190 200
LSAKKKESHL QEADTQIDRE HQNFYEASLE YVFKIQEVQE KKKFEFVEPL
210 220 230 240 250
LSFLQGLFTF YHEGYELAQE FAPYKQQLQF NLQNTRNNFE STRQEVERLM
260 270 280 290 300
QRMKSANQDY RPPSQWTMEG YLYVQEKRPL GFTWIKHYCT YDKGSKTFTM
310 320 330 340 350
SVSEMKSSGK MNGLVTSSPE MFKLKSCIRR KTDSIDKRFC FDIEVVERHG
360 370 380 390 400
IITLQAFSEA NRKLWLEAMD GKEPIYTLPA IISKKEEMYL NEAGFNFVRK
410 420 430 440 450
CIQAVETRGI TILGLYRIGG VNSKVQKLMN TTFSPKSPPD IDIDIELWDN
460 470 480 490 500
KTITSGLKNY LRCLAEPLMT YKLHKDFIIA VKSDDQNYRV EAVHALVHKL
510 520 530 540 550
PEKNREMLDI LIKHLVKVSL HSQQNLMTVS NLGVIFGPTL MRAQEETVAA
560 570 580 590 600
MMNIKFQNIV VEILIEHYEK IFHTAPDPSI PLPQPQSRSG SRRTRAICLS
610 620 630 640 650
TGSRKPRGRY TPCLAEPDSD SYSSSPDSTP MGSIESLSSH SSEQNSTTKS
660 670 680 690 700
ASCQPREKSG GIPWIATPSS SNGQKSLGLW TTSPESSSRE DATKTDAESD
710 720 730 740 750
CQSVASVTSP GDVSPPIDLV KKEPYGLSGL KRASASSLRS ISAAEGNKSY
760 770 780 790 800
SGSIQSLTSV GSKETPKASP NPDLPPKMCR RLRLDTASSN GYQRPGSVVA
810 820 830 840 850
AKAQLFENVG SPKPVSSGRQ AKAMYSCKAE HSHELSFPQG AIFSNVYPSV
860 870
EPGWLKATYE GKTGLVPENY VVFL
Length:874
Mass (Da):98,569
Last modified:June 20, 2018 - v1
Checksum:i3828623C52C52629
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R9CGB4A0A2R9CGB4_PANPA
Uncharacterized protein
ARHGAP42
840Annotation score:
A0A2R9CG68A0A2R9CG68_PANPA
Uncharacterized protein
ARHGAP42
853Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJFE02100762 Genomic DNA No translation available.
AJFE02100763 Genomic DNA No translation available.
AJFE02100764 Genomic DNA No translation available.
AJFE02100765 Genomic DNA No translation available.
AJFE02100766 Genomic DNA No translation available.
AJFE02100767 Genomic DNA No translation available.
AJFE02100768 Genomic DNA No translation available.
RefSeqiXP_003828445.1, XM_003828397.3

Genome annotation databases

EnsembliENSPPAT00000063869; ENSPPAP00000040948; ENSPPAG00000043081
GeneIDi100974516
KEGGipps:100974516

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJFE02100762 Genomic DNA No translation available.
AJFE02100763 Genomic DNA No translation available.
AJFE02100764 Genomic DNA No translation available.
AJFE02100765 Genomic DNA No translation available.
AJFE02100766 Genomic DNA No translation available.
AJFE02100767 Genomic DNA No translation available.
AJFE02100768 Genomic DNA No translation available.
RefSeqiXP_003828445.1, XM_003828397.3

3D structure databases

SMRiA0A2R9CIT5
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPPAT00000063869; ENSPPAP00000040948; ENSPPAG00000043081
GeneIDi100974516
KEGGipps:100974516

Organism-specific databases

CTDi143872

Phylogenomic databases

GeneTreeiENSGT00930000150818
KOiK20651

Family and domain databases

Gene3Di1.10.555.10, 1 hit
1.20.1270.60, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR027267 AH/BAR_dom_sf
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR008936 Rho_GTPase_activation_prot
IPR000198 RhoGAP_dom
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00169 PH, 1 hit
PF00620 RhoGAP, 1 hit
PF14604 SH3_9, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00324 RhoGAP, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF103657 SSF103657, 1 hit
SSF48350 SSF48350, 1 hit
SSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS50238 RHOGAP, 1 hit
PS50002 SH3, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2R9CIT5_PANPA
AccessioniPrimary (citable) accession number: A0A2R9CIT5
Entry historyiIntegrated into UniProtKB/TrEMBL: June 20, 2018
Last sequence update: June 20, 2018
Last modified: November 7, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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