Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 10 (31 Jul 2019)
Sequence version 1 (20 Jun 2018)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein
Submitted name:

Uncharacterized protein

Gene

RBM25

Organism
Pan paniscus (Pygmy chimpanzee) (Bonobo)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-bindingPROSITE-ProRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RBM25Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPan paniscus (Pygmy chimpanzee) (Bonobo)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9597 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000240080 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
A0A2R9BTX8

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini87 – 164RRMInterPro annotationAdd BLAST78
Domaini750 – 843PWIInterPro annotationAdd BLAST94

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 30DisorderedSequence analysisAdd BLAST30
Regioni171 – 202DisorderedSequence analysisAdd BLAST32
Regioni219 – 243DisorderedSequence analysisAdd BLAST25
Regioni280 – 442DisorderedSequence analysisAdd BLAST163
Regioni498 – 688DisorderedSequence analysisAdd BLAST191

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi187 – 202PolyampholyteSequence analysisAdd BLAST16
Compositional biasi228 – 243PolyampholyteSequence analysisAdd BLAST16
Compositional biasi498 – 580PolyampholyteSequence analysisAdd BLAST83
Compositional biasi581 – 606AcidicSequence analysisAdd BLAST26
Compositional biasi620 – 639PolarSequence analysisAdd BLAST20

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00730000111019

KEGG Orthology (KO)

More...
KOi
K12822

Identification of Orthologs from Complete Genome Data

More...
OMAi
FGFCEFD

Family and domain databases

Conserved Domains Database

More...
CDDi
cd12446 RRM_RBM25, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.330, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR002483 PWI_dom
IPR036483 PWI_dom_sf
IPR035979 RBD_domain_sf
IPR034268 RBM25_RRM
IPR000504 RRM_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01480 PWI, 1 hit
PF00076 RRM_1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00311 PWI, 1 hit
SM00360 RRM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF101233 SSF101233, 1 hit
SSF54928 SSF54928, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51025 PWI, 1 hit
PS50102 RRM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A2R9BTX8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSFPPHLNRP PMGIPALPPG IPPPQFPGFP PPVPPGTPMI PVPMSIMAPA
60 70 80 90 100
PTVLVPTVSM VGKHLGARKD HPGLKAKEND ENCGPTTTVF VGNISEKASD
110 120 130 140 150
MLIRQLLAKC GLVLSWKRVQ GASGKLQAFG FCEYKEPEST LRALRLLHDL
160 170 180 190 200
QIGEKKLLVK VDAKTKAQLD EWKAKKKASN GNARPETVTN DDEEALDEET
210 220 230 240 250
KRRDQMIKGA IEVLIREYSS ELNAPSQESD SHPRKKKKEK KEDIFRRFPV
260 270 280 290 300
APLIPYPLIT KEDINAIEME EDKRDLISRE ISKFRDTHKK LEEEKGKKEK
310 320 330 340 350
ERQEIEKERR ERERERERER ERRERERERE REREREKEKE RERERERDRD
360 370 380 390 400
RDRTKERDRD RDRERDRDRD RERSSDRNKD RSRSREKSRD RERERERERE
410 420 430 440 450
RERERERERE RERERERERE REREREKDKK RDREEDEEDA YERRKLERKL
460 470 480 490 500
REKEAAYQER LKNWEIRERK KTREYEKEAE REEERRREMA KEAKRLKEFL
510 520 530 540 550
EDYDDDRDDP KYYRGSALQK RLRDREKEME ADERDRKREK EELEEIRQRL
560 570 580 590 600
LAEGHPDPDA ELQRMEQEAE RRRQPQIKQE PESEEEEEEK QEKEEKREEP
610 620 630 640 650
MEEEEEPEQK PCLKPTLRPI SSAPSVSSAS GNATPNTPGD ESPCGIIIPH
660 670 680 690 700
ENSPDQQQPE EHRPKIGLSL KLGASNSPGQ PNSVKRKKLP VDSVFNKFED
710 720 730 740 750
EDSDDVPRKR KLVPLDYGED DKNATKGTVN TEEKRKHIKS LIEKIPTAKP
760 770 780 790 800
ELFAYPLDWS IVDSILMERR IRPWINKKII EYIGEEEATL VDFVCSKVMA
810 820 830 840
HSSPQSILDD VAMVLDEEAE VFIVKMWRLL IYETEAKKIG LVK
Length:843
Mass (Da):100,185
Last modified:June 20, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i80534590147A342A
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R9BUJ7A0A2R9BUJ7_PANPA
RRM domain-containing protein
RBM25
294Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJFE02084859 Genomic DNA No translation available.
AJFE02084860 Genomic DNA No translation available.
AJFE02084861 Genomic DNA No translation available.
AJFE02084862 Genomic DNA No translation available.
AJFE02084863 Genomic DNA No translation available.
AJFE02084864 Genomic DNA No translation available.
AJFE02084865 Genomic DNA No translation available.
AJFE02084866 Genomic DNA No translation available.
AJFE02084867 Genomic DNA No translation available.
AJFE02084868 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_003824181.1, XM_003824133.3
XP_008976104.1, XM_008977856.1
XP_008976105.1, XM_008977857.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSPPAT00000055993; ENSPPAP00000033122; ENSPPAG00000039402

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100968641

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pps:100968641

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJFE02084859 Genomic DNA No translation available.
AJFE02084860 Genomic DNA No translation available.
AJFE02084861 Genomic DNA No translation available.
AJFE02084862 Genomic DNA No translation available.
AJFE02084863 Genomic DNA No translation available.
AJFE02084864 Genomic DNA No translation available.
AJFE02084865 Genomic DNA No translation available.
AJFE02084866 Genomic DNA No translation available.
AJFE02084867 Genomic DNA No translation available.
AJFE02084868 Genomic DNA No translation available.
RefSeqiXP_003824181.1, XM_003824133.3
XP_008976104.1, XM_008977856.1
XP_008976105.1, XM_008977857.2

3D structure databases

SMRiA0A2R9BTX8
ModBaseiSearch...

Genome annotation databases

EnsembliENSPPAT00000055993; ENSPPAP00000033122; ENSPPAG00000039402
GeneIDi100968641
KEGGipps:100968641

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
58517

Phylogenomic databases

GeneTreeiENSGT00730000111019
KOiK12822
OMAiFGFCEFD

Family and domain databases

CDDicd12446 RRM_RBM25, 1 hit
Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR002483 PWI_dom
IPR036483 PWI_dom_sf
IPR035979 RBD_domain_sf
IPR034268 RBM25_RRM
IPR000504 RRM_dom
PfamiView protein in Pfam
PF01480 PWI, 1 hit
PF00076 RRM_1, 1 hit
SMARTiView protein in SMART
SM00311 PWI, 1 hit
SM00360 RRM, 1 hit
SUPFAMiSSF101233 SSF101233, 1 hit
SSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS51025 PWI, 1 hit
PS50102 RRM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2R9BTX8_PANPA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2R9BTX8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 20, 2018
Last sequence update: June 20, 2018
Last modified: July 31, 2019
This is version 10 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again