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Entry version 7 (03 Jul 2019)
Sequence version 1 (20 Jun 2018)
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Protein
Submitted name:

Uncharacterized protein

Gene
N/A
Organism
Pan paniscus (Pygmy chimpanzee) (Bonobo)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingPROSITE-ProRule annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPan paniscus (Pygmy chimpanzee) (Bonobo)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9597 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaePan
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000240080 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati89 – 104XinPROSITE-ProRule annotationAdd BLAST16
Repeati121 – 136XinPROSITE-ProRule annotationAdd BLAST16
Repeati151 – 166XinPROSITE-ProRule annotationAdd BLAST16
Repeati186 – 201XinPROSITE-ProRule annotationAdd BLAST16
Repeati226 – 241XinPROSITE-ProRule annotationAdd BLAST16
Repeati264 – 279XinPROSITE-ProRule annotationAdd BLAST16
Repeati302 – 317XinPROSITE-ProRule annotationAdd BLAST16
Repeati340 – 355XinPROSITE-ProRule annotationAdd BLAST16
Repeati376 – 391XinPROSITE-ProRule annotationAdd BLAST16
Repeati436 – 451XinPROSITE-ProRule annotationAdd BLAST16
Repeati507 – 522XinPROSITE-ProRule annotationAdd BLAST16
Repeati545 – 560XinPROSITE-ProRule annotationAdd BLAST16
Repeati589 – 604XinPROSITE-ProRule annotationAdd BLAST16
Repeati621 – 636XinPROSITE-ProRule annotationAdd BLAST16
Repeati654 – 669XinPROSITE-ProRule annotationAdd BLAST16
Repeati691 – 706XinPROSITE-ProRule annotationAdd BLAST16
Repeati723 – 738XinPROSITE-ProRule annotationAdd BLAST16

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 48DisorderedSequence analysisAdd BLAST48
Regioni132 – 151DisorderedSequence analysisAdd BLAST20
Regioni406 – 435DisorderedSequence analysisAdd BLAST30
Regioni455 – 479DisorderedSequence analysisAdd BLAST25
Regioni564 – 591DisorderedSequence analysisAdd BLAST28
Regioni943 – 999DisorderedSequence analysisAdd BLAST57
Regioni1062 – 1121DisorderedSequence analysisAdd BLAST60

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi21 – 35Pro-richSequence analysisAdd BLAST15
Compositional biasi412 – 427PolarSequence analysisAdd BLAST16
Compositional biasi564 – 579PolyampholyteSequence analysisAdd BLAST16
Compositional biasi1062 – 1106PolarSequence analysisAdd BLAST45

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Xin repeats bind F-actin.PROSITE-ProRule annotation

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the Xin family.PROSITE-ProRule annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00530000063779

Identification of Orthologs from Complete Genome Data

More...
OMAi
QGYRWMF

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012510 Actin-binding_Xin_repeat
IPR030072 XIRP1/XIRP2

The PANTHER Classification System

More...
PANTHERi
PTHR22591 PTHR22591, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08043 Xin, 9 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51389 XIN, 17 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2R9AE02-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADTQTQVAP TPTMRMATAE DLPLPPPPAL EDLPLPPPKE SFSKFHQQRQ
60 70 80 90 100
ASELRRLYRH IHPELRKNLA EAVAEDLAEV LGSEEPTEGD VQCMRWIFEN
110 120 130 140 150
WRLDAIGDHE RPAAKEPVLC GDVQATSRKF EEGSFANSTD QEPTRPQPGG
160 170 180 190 200
GDVRAARWLF ETKPLDELTG QAKELEATVR EPAASGDVQG TRMLFETRPL
210 220 230 240 250
DRLGSRPSLQ EQSPLELRSE IQELKGDVKK TVKLFQTEPL CAIQDAEGAI
260 270 280 290 300
HEVKAACREE IQSNAVRSAR WLFETRPLDA INQDPSQVRV IRGISLEEGA
310 320 330 340 350
RPDVSATRWI FETQPLDAIR EILVDEKDFQ PSPDLIPPGP DVQQQRHLFE
360 370 380 390 400
TRALDTLKGD EEAGAEAPPK EEVVPGDVCS TLWLFETKPL DAFRDKVQVG
410 420 430 440 450
HLQRVDPQDG EGHLSSDSSS ALPFSQSAPQ RDGLKGDVKT FKNLFETLPL
460 470 480 490 500
DSIGQGEVLA HGSPSREEGT DSAGQAQGIG SPVYAMQDSK GRLHALTSVS
510 520 530 540 550
REQIVGGDVQ GYRWMFETQP LDQLGRSPST IDVVRGITRQ EVVAGDVGTA
560 570 580 590 600
RWLFETQPLE MIHQREQQER QKEEGKSQGD PQPEAPPKGD VQTIRWLFET
610 620 630 640 650
CPMSELAEKQ GSEVTDPTAK AEAQSCTWMF KPQPVDRPVG SREQHLQVSQ
660 670 680 690 700
VPAGERQTDR HVFETEPLQA SGRPCGRGPV RYCSRVEIPS GQVSRQKEVF
710 720 730 740 750
QALEAGKKEE QEPRVIAGSI PAGSVHKFTW LFENCPMGSL AAESIQGGNL
760 770 780 790 800
LEEQPMSPSG NRMQESQETA AEGTLRTLHA TPGILHHGGI LMEARGPGEL
810 820 830 840 850
CLAKYVLSGT GQGHPYIRKE ELVSGELPRI ICQVLRRPDV DQQGLLVQED
860 870 880 890 900
PTGQLQLKPL RLPTPGSSGN IEDMDPELQQ LLACGLGTSV ARTGLVMQET
910 920 930 940 950
EQGLVALTAY SLQPRLTSKA SERSSVQLLA SCIDKGDLSG LHSLRWEPPA
960 970 980 990 1000
DPSPVPASEG AQSLPPTESI IHVPPLDPSM GMGHLRASGA TPCPPQAIGK
1010 1020 1030 1040 1050
AVPLAGEAAA PAQLQNTEKQ EDSHSGQKGM AVLGKSEGAT TTPPGPGAPD
1060 1070 1080 1090 1100
LLAAMQSLRM ATAEAQSLHQ QVLNKHKQGP TPTATSNPIQ DGLRKAGATQ
1110 1120
SNIRPGGGSD PRIPAAPRKL L
Length:1,121
Mass (Da):121,884
Last modified:June 20, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1491E9446240FAEF
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AJFE02091543 Genomic DNA No translation available.

NCBI Reference Sequences

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RefSeqi
XP_014199640.1, XM_014344154.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSPPAT00000036422; ENSPPAP00000013748; ENSPPAG00000030043

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
100989415

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJFE02091543 Genomic DNA No translation available.
RefSeqiXP_014199640.1, XM_014344154.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPPAT00000036422; ENSPPAP00000013748; ENSPPAG00000030043
GeneIDi100989415

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
165904

Phylogenomic databases

GeneTreeiENSGT00530000063779
OMAiQGYRWMF

Family and domain databases

InterProiView protein in InterPro
IPR012510 Actin-binding_Xin_repeat
IPR030072 XIRP1/XIRP2
PANTHERiPTHR22591 PTHR22591, 2 hits
PfamiView protein in Pfam
PF08043 Xin, 9 hits
PROSITEiView protein in PROSITE
PS51389 XIN, 17 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2R9AE02_PANPA
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2R9AE02
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 20, 2018
Last sequence update: June 20, 2018
Last modified: July 3, 2019
This is version 7 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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