UniProtKB - A0A2R8Y6A5 (A0A2R8Y6A5_HUMAN)
Protein
Tubulin--tyrosine ligase-like protein 9
Gene
TTLL9
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
GO - Biological processi
- cellular protein modification process Source: InterPro
Keywordsi
Ligand | ATP-bindingARBA annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Tubulin--tyrosine ligase-like protein 9ARBA annotation |
Gene namesi | Name:TTLL9Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:16118, TTLL9 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 21 | DisorderedSequence analysisAdd BLAST | 21 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 96 – 119 | Sequence analysisAdd BLAST | 24 |
Sequence similaritiesi
Belongs to the tubulin--tyrosine ligase family.ARBA annotation
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000159879 |
Family and domain databases
Gene3Di | 3.30.1490.20, 1 hit |
InterProi | View protein in InterPro IPR013815, ATP_grasp_subdomain_1 IPR004344, TTL/TTLL_fam IPR027751, TTLL9 |
PANTHERi | PTHR12241:SF39, PTHR12241:SF39, 1 hit |
Pfami | View protein in Pfam PF03133, TTL, 1 hit |
PROSITEi | View protein in PROSITE PS51221, TTL, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All
A0A2R8Y6A5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSRPKNQNYK GHGLSKGKER EQRASIRFKT TLMNTLMDVL RHRPGWVEVK
60 70 80 90 100
DEGEWDFYWC DVSWLRENFD HTYMDEHVRI SHFRNHYELT RKNYMVKNLK
110 120 130 140 150
RFRKQLEREA GKLEAAKCDF FPKTFEMPCE YHLFVEEFRK NPGITWIMKP
160 170 180 190 200
VARSQGKGIF LFRRLKDIVD WRKDTRSSDD QKDDIPVENY VAQRYIENPY
210 220 230 240 250
LIGGRKFDLR VYVLVMSYIP LRAWLYRDGF ARFSNTRFTL NSIDDQYVHL
260 270 280 290 300
TNVAVQKTSP DYHPKKGCKW TLQRFRQYLA SKHGPEAVET LFRDIDNIFV
310 320 330 340 350
KSLQSVQKVI ISDKHCFELY GYDILIDQDL KPWLLEVNAS PSLTASSQED
360 370
YELKTCLLED TLHVVDMEAR SLRADSPCW
Computationally mapped potential isoform sequencesi
There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketQ3SXZ7 | TTLL9_HUMAN | Probable tubulin polyglutamylase TT... | TTLL9 C20orf125 | 439 | Annotation score: | ||
B4DZ96 | B4DZ96_HUMAN | Tubulin--tyrosine ligase-like prote... | TTLL9 | 279 | Annotation score: | ||
A0A087X135 | A0A087X135_HUMAN | Tubulin--tyrosine ligase-like prote... | TTLL9 | 341 | Annotation score: | ||
A0A087WXF5 | A0A087WXF5_HUMAN | Tubulin--tyrosine ligase-like prote... | TTLL9 | 225 | Annotation score: | ||
A0A087WWB8 | A0A087WWB8_HUMAN | Probable tubulin polyglutamylase TT... | TTLL9 | 184 | Annotation score: | ||
A0A0A0MR21 | A0A0A0MR21_HUMAN | Probable tubulin polyglutamylase TT... | TTLL9 | 105 | Annotation score: | ||
A0A2R8YD21 | A0A2R8YD21_HUMAN | Probable tubulin polyglutamylase TT... | TTLL9 | 59 | Annotation score: | ||
A0A087WYL2 | A0A087WYL2_HUMAN | Probable tubulin polyglutamylase TT... | TTLL9 | 39 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL031658 Genomic DNA No translation available. AL160175 Genomic DNA No translation available. AL359765 Genomic DNA No translation available. |
RefSeqi | XP_016883188.1, XM_017027699.1 |
Genome annotation databases
Ensembli | ENST00000644596; ENSP00000495394; ENSG00000131044 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AL031658 Genomic DNA No translation available. AL160175 Genomic DNA No translation available. AL359765 Genomic DNA No translation available. |
RefSeqi | XP_016883188.1, XM_017027699.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | A0A2R8Y6A5 |
Genome annotation databases
Ensembli | ENST00000644596; ENSP00000495394; ENSG00000131044 |
Organism-specific databases
HGNCi | HGNC:16118, TTLL9 |
OpenTargetsi | ENSG00000131044 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000159879 |
Miscellaneous databases
ChiTaRSi | TTLL9, human |
Gene expression databases
ExpressionAtlasi | A0A2R8Y6A5, baseline and differential |
Family and domain databases
Gene3Di | 3.30.1490.20, 1 hit |
InterProi | View protein in InterPro IPR013815, ATP_grasp_subdomain_1 IPR004344, TTL/TTLL_fam IPR027751, TTLL9 |
PANTHERi | PTHR12241:SF39, PTHR12241:SF39, 1 hit |
Pfami | View protein in Pfam PF03133, TTL, 1 hit |
PROSITEi | View protein in PROSITE PS51221, TTL, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A2R8Y6A5_HUMAN | |
Accessioni | A0A2R8Y6A5Primary (citable) accession number: A0A2R8Y6A5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 20, 2018 |
Last sequence update: | June 20, 2018 | |
Last modified: | October 7, 2020 | |
This is version 12 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |