UniProtKB - A0A2R8QJX9 (A0A2R8QJX9_DANRE)
Protein
Submitted name:
ADAM metallopeptidase domain 28
Gene
adam28
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- endopeptidase activity Source: GO_Central
- metalloendopeptidase activity Source: InterPro
- metallopeptidase activity Source: GO_Central
Names & Taxonomyi
Protein namesi | Submitted name: ADAM metallopeptidase domain 28Imported |
Gene namesi | Name:adam28Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-060929-532, adam28 |
Subcellular locationi
Plasma Membrane
- plasma membrane Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 22 | Sequence analysisAdd BLAST | 22 | |
ChainiPRO_5015339278 | 23 – 293 | Sequence analysisAdd BLAST | 271 |
Keywords - PTMi
Disulfide bondARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 200 – 293 | Peptidase M12BInterPro annotationAdd BLAST | 94 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 206 – 226 | Sequence analysisAdd BLAST | 21 |
Keywords - Domaini
Coiled coilSequence analysis, SignalSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000156716 |
Family and domain databases
CDDi | cd04269, ZnMc_adamalysin_II_like, 1 hit |
Gene3Di | 3.40.390.10, 1 hit |
InterProi | View protein in InterPro IPR024079, MetalloPept_cat_dom_sf IPR001590, Peptidase_M12B IPR002870, Peptidase_M12B_N IPR034027, Reprolysin_adamalysin |
Pfami | View protein in Pfam PF01562, Pep_M12B_propep, 1 hit PF01421, Reprolysin, 1 hit |
PROSITEi | View protein in PROSITE PS50215, ADAM_MEPRO, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
A0A2R8QJX9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAQRHLMLWI FTLCVSLDPS VGHIHELHGK VYEIVRPIRL HDLQKRDLQS
60 70 80 90 100
RPDRVKYAMT LGGRDIEMHL QKNTGMLTKD YSETYYTDDG MLVTTTPADL
110 120 130 140 150
DLCYYHGKIL NDSASLVSMS TCDGLRGYFQ TAEQRFLIEP LSEDSDGDHA
160 170 180 190 200
VFKYEDVNEA TPRVCGVTNT TWDESGDGVP PRILKTRSRS SGPTLFQRQK
210 220 230 240 250
YNEFFLVADN REYKKLNSDL EKLRKRIFEI INFINNVYKE INTFVALTGF
260 270 280 290
EVWTDNDKIT VSAASGATLD SFTKWRNSDL IKRQRHDNAH LLT
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA3KQJ0 | A3KQJ0_DANRE | ADAM metallopeptidase domain 28 | adam28 | 762 | Annotation score: | ||
F1QDC4 | F1QDC4_DANRE | ADAM metallopeptidase domain 28 | adam28 | 765 | Annotation score: | ||
A0A2R8QF72 | A0A2R8QF72_DANRE | ADAM metallopeptidase domain 28 | adam28 | 293 | Annotation score: | ||
A0A2R8QP33 | A0A2R8QP33_DANRE | ADAM metallopeptidase domain 28 | adam28 | 286 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX666060 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENSDART00000180251; ENSDARP00000152657; ENSDARG00000035514 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX666060 Genomic DNA No translation available. |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
Ensembli | ENSDART00000180251; ENSDARP00000152657; ENSDARG00000035514 |
Organism-specific databases
ZFINi | ZDB-GENE-060929-532, adam28 |
Phylogenomic databases
GeneTreei | ENSGT00940000156716 |
Gene expression databases
ExpressionAtlasi | A0A2R8QJX9, baseline |
Family and domain databases
CDDi | cd04269, ZnMc_adamalysin_II_like, 1 hit |
Gene3Di | 3.40.390.10, 1 hit |
InterProi | View protein in InterPro IPR024079, MetalloPept_cat_dom_sf IPR001590, Peptidase_M12B IPR002870, Peptidase_M12B_N IPR034027, Reprolysin_adamalysin |
Pfami | View protein in Pfam PF01562, Pep_M12B_propep, 1 hit PF01421, Reprolysin, 1 hit |
PROSITEi | View protein in PROSITE PS50215, ADAM_MEPRO, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | A0A2R8QJX9_DANRE | |
Accessioni | A0A2R8QJX9Primary (citable) accession number: A0A2R8QJX9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 20, 2018 |
Last sequence update: | June 20, 2018 | |
Last modified: | December 2, 2020 | |
This is version 10 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |