Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 11 (07 Oct 2020)
Sequence version 1 (20 Jun 2018)
Previous versions | rss
Add a publicationFeedback
Protein
Submitted name:

IQ motif and Sec7 domain ArfGEF 2a

Gene

iqsec2a

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
IQ motif and Sec7 domain ArfGEF 2aImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:iqsec2aImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesDanionidaeDanioninaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 8

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-170302-3, iqsec2a

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
A0A2R8Q8B1, baseline

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini574 – 767SEC7InterPro annotationAdd BLAST194

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni178 – 231DisorderedSequence analysisAdd BLAST54
Regioni251 – 276DisorderedSequence analysisAdd BLAST26
Regioni328 – 371DisorderedSequence analysisAdd BLAST44
Regioni383 – 573DisorderedSequence analysisAdd BLAST191
Regioni976 – 1019DisorderedSequence analysisAdd BLAST44
Regioni1037 – 1135DisorderedSequence analysisAdd BLAST99
Regioni1191 – 1289DisorderedSequence analysisAdd BLAST99
Regioni1403 – 1487DisorderedSequence analysisAdd BLAST85

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi178 – 221PolarSequence analysisAdd BLAST44
Compositional biasi404 – 424PolarSequence analysisAdd BLAST21
Compositional biasi461 – 483BasicSequence analysisAdd BLAST23
Compositional biasi487 – 502Pro-richSequence analysisAdd BLAST16
Compositional biasi503 – 549PolarSequence analysisAdd BLAST47
Compositional biasi988 – 1010PolarSequence analysisAdd BLAST23
Compositional biasi1065 – 1084PolarSequence analysisAdd BLAST20
Compositional biasi1093 – 1125Pro-richSequence analysisAdd BLAST33
Compositional biasi1191 – 1253Pro-richSequence analysisAdd BLAST63
Compositional biasi1410 – 1446Pro-richSequence analysisAdd BLAST37
Compositional biasi1461 – 1487PolarSequence analysisAdd BLAST27

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the BRAG family.ARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159667

Family and domain databases

Conserved Domains Database

More...
CDDi
cd13318, PH_IQSEC, 1 hit
cd00171, Sec7, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1000.11, 1 hit
2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000048, IQ_motif_EF-hand-BS
IPR033742, IQSEC_PH
IPR011993, PH-like_dom_sf
IPR001849, PH_domain
IPR023394, Sec7_C_sf
IPR000904, Sec7_dom
IPR035999, Sec7_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16453, IQ_SEC7_PH, 1 hit
PF01369, Sec7, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00233, PH, 1 hit
SM00222, Sec7, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48425, SSF48425, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50096, IQ, 1 hit
PS50190, SEC7, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

A0A2R8Q8B1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MWCINCASDK TPAILHNKLV YCVEGDPQCP DTTSFSDSTC SQGPYLGNSE
60 70 80 90 100
RYGNIRNIPG PQGPPVGTAS PASLAWAQRS RHQPASLALR KQEEEESKRC
110 120 130 140 150
KALSDSYELS TDLQDKKVEM LERKYGGYFL SRRAARTIQT AFRQYRMNKN
160 170 180 190 200
FQRLRSSASE SRMTRRIILS NMRSQYSFDE RQPQVQPQTP QQQQGRYTSH
210 220 230 240 250
HTSGTAGQTG STNTQQETDS PAHCPSDREE YSHADDAFNK QVTSLADSMD
260 270 280 290 300
DTLTCQSGRG DSQDGGEGAR EESVDFGECV WSNKPTSRRG VVGEQERLGV
310 320 330 340 350
MHEDSTATSY SDVTLYMDDG MPCSPLSIER VPSSTDTEYW GVSSGVGGRE
360 370 380 390 400
DSRDTEGGGS TNSRRSTPCT ECRDFRLRGS HLPVLTIEPP SDSSVDMSDR
410 420 430 440 450
SDRGSLSRQL LYEQEPTAGG SPQGTLKHNP APRMPNPCAA QGQTRPTGRP
460 470 480 490 500
IPSPLPTHLP HHAMMHHHHH PHLHHPLHHH PLPHMHHPYP DPTSPSPTQP
510 520 530 540 550
PLTPLSSSSS APLPASGMEQ SDGDNDSLNS TTNSNETINC SSGSSSRDSL
560 570 580 590 600
REPLPPLGKQ TYQRESRHSW DSPAFNNDVV QRRHYRIGLN LFNKKPEKGI
610 620 630 640 650
QYLIERGFVS DTPVGIARFI LERKGLSRQM IGEFLGNRQK QFNKDVLDCV
660 670 680 690 700
LDEMDFSGMD LDDALRKFQA QIKVQGEAQK VERLVEAFSQ RYCVCNPALV
710 720 730 740 750
RQFQNPDTIF ILAFAIILLN TDMYSPNVKA ERKMKLEDFI KNLRGVDNGQ
760 770 780 790 800
DIPRDLLVGI YQRIQKWELR TNDDHVSQVQ AVERVIVGKK PVLSLPHRRL
810 820 830 840 850
VCCCQLYEVP DPNRPQRSGV HQREVFLFND LLVVTKIFQK KKTSVTYSFR
860 870 880 890 900
QSFPLVEMQV HMFQNSYYAH GIRLTSAMPG AERKVLIVFN APSQQDRTRF
910 920 930 940 950
TSDLRESIAE VQDMEKYRVE SELEKQKGVM RPGLLSGEVS SVGGMKTEAV
960 970 980 990 1000
NGTLGRPSLD DTYAAGEGLK RTALSSSLRD LSDTGKRGRR NSVGSLDSTI
1010 1020 1030 1040 1050
EGSIINSPQP HQRLPMGGAV PGCYGLEDYR PHRPILSPGV GVGGGPGQLH
1060 1070 1080 1090 1100
NAVGNMVGGS GTSDRGGGPG SSSGGSNSGS FLGSLFGSKR GKPPAPLIPP
1110 1120 1130 1140 1150
GPHYPAPVRP PTTGGPPPPS PSALSQSDPG GPSKIQALHA QYCHNNFGQP
1160 1170 1180 1190 1200
PPPYHHHHRY HMQVGAPGHP PAMHPPNIHP PAMHPPNIHP PAMHPPNIHP
1210 1220 1230 1240 1250
PAMHPPNIHP PAMHPPNIHP PAMHPPNIHP PAMHPTNMHP PSVHPPSMHP
1260 1270 1280 1290 1300
PSGHPPAMHH TLQRGSLPRR GPAAPSHPQL QQQLSHHAMQ QGRYGNMACT
1310 1320 1330 1340 1350
PPPLSPHSPH SPVGPFNFYH VHGNPIRLAR VPGPTGKLPL TLSHSQPHPH
1360 1370 1380 1390 1400
AHSHGHSHTH NHLVHVHSPH PELHHSGQTH FVFSPPPQAP SAITARHIPQ
1410 1420 1430 1440 1450
GVSHYIPQYP PLSSIPPPPP HSPLPPPSSP HTPLTPLTPL SPLAPQLPGP
1460 1470 1480
MGAQSGGPGG GGGSGASNSS TVGSSKSKPI NRISTVV
Length:1,487
Mass (Da):162,611
Last modified:June 20, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC2B82D0FB1F31D31
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2R8QGT6A0A2R8QGT6_DANRE
IQ motif and Sec7 domain ArfGEF 2a
iqsec2a
1,013Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2L9N5A0A0G2L9N5_DANRE
IQ motif and Sec7 domain ArfGEF 2a
iqsec2a
1,629Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8Q8W8A0A2R8Q8W8_DANRE
IQ motif and Sec7 domain ArfGEF 2a
iqsec2a
1,492Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8QUT2A0A2R8QUT2_DANRE
IQ motif and Sec7 domain ArfGEF 2a
iqsec2a
1,281Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8Q462A0A2R8Q462_DANRE
IQ motif and Sec7 domain ArfGEF 2a
iqsec2a
858Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2R8QNV2A0A2R8QNV2_DANRE
IQ motif and Sec7 domain ArfGEF 2a
iqsec2a
825Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CR388083 Genomic DNA No translation available.
CT025733 Genomic DNA No translation available.
CT583651 Genomic DNA No translation available.

NCBI Reference Sequences

More...
RefSeqi
XP_017212949.1, XM_017357460.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000181258; ENSDARP00000147502; ENSDARG00000102125

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
560461

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR388083 Genomic DNA No translation available.
CT025733 Genomic DNA No translation available.
CT583651 Genomic DNA No translation available.
RefSeqiXP_017212949.1, XM_017357460.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSDART00000181258; ENSDARP00000147502; ENSDARG00000102125
GeneIDi560461

Organism-specific databases

ZFINiZDB-GENE-170302-3, iqsec2a

Phylogenomic databases

GeneTreeiENSGT00940000159667

Gene expression databases

ExpressionAtlasiA0A2R8Q8B1, baseline

Family and domain databases

CDDicd13318, PH_IQSEC, 1 hit
cd00171, Sec7, 1 hit
Gene3Di1.10.1000.11, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR000048, IQ_motif_EF-hand-BS
IPR033742, IQSEC_PH
IPR011993, PH-like_dom_sf
IPR001849, PH_domain
IPR023394, Sec7_C_sf
IPR000904, Sec7_dom
IPR035999, Sec7_dom_sf
PfamiView protein in Pfam
PF16453, IQ_SEC7_PH, 1 hit
PF01369, Sec7, 1 hit
SMARTiView protein in SMART
SM00233, PH, 1 hit
SM00222, Sec7, 1 hit
SUPFAMiSSF48425, SSF48425, 1 hit
PROSITEiView protein in PROSITE
PS50096, IQ, 1 hit
PS50190, SEC7, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2R8Q8B1_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2R8Q8B1
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 20, 2018
Last sequence update: June 20, 2018
Last modified: October 7, 2020
This is version 11 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again