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Entry version 23 (10 Feb 2021)
Sequence version 1 (20 Jun 2018)
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Protein

DNA gyrase subunit B

Gene

gyrB

Organism
Mycobacterium tuberculosis
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.UniRule annotation

Miscellaneous

Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.UniRule annotation

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

  • ATP-dependent breakage, passage and rejoining of double-stranded DNA.UniRule annotationARBA annotation EC:5.6.2.2

<p>This subsection of the 'Function' section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Mg2+ARBA annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionIsomerase, TopoisomeraseUniRule annotationARBA annotation
LigandATP-bindingUniRule annotationARBA annotation, MagnesiumARBA annotation, Metal-bindingARBA annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA gyrase subunit BUniRule annotation (EC:5.6.2.2UniRule annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:gyrBUniRule annotationImported
ORF Names:AYJ03_000025Imported, DSI38_08120Imported, E5M52_15230Imported, E5M78_15120Imported, FRD82_14680Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMycobacterium tuberculosisImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri1773 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaActinobacteriaCorynebacterialesMycobacteriaceaeMycobacteriumMycobacterium tuberculosis complex
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000321489 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000256245 Componenti: Unassembled WGS sequence
  • UP000075723 Componenti: Chromosome
  • UP000298278 Componenti: Unassembled WGS sequence
  • UP000297584 Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.

UniRule annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini453 – 567ToprimInterPro annotationAdd BLAST115

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the type II topoisomerase GyrB family.ARBA annotation
Belongs to the type II topoisomerase family.UniRule annotation

Family and domain databases

Conserved Domains Database

More...
CDDi
cd03366, TOPRIM_TopoIIA_GyrB, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.230.10, 1 hit
3.30.565.10, 1 hit
3.40.50.670, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_01898, GyrB, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002288, DNA_gyrase_B_C
IPR011557, GyrB
IPR003594, HATPase_C
IPR036890, HATPase_C_sf
IPR020568, Ribosomal_S5_D2-typ_fold
IPR014721, Ribosomal_S5_D2-typ_fold_subgr
IPR001241, Topo_IIA
IPR013760, Topo_IIA-like_dom_sf
IPR013759, Topo_IIA_B_C
IPR013506, Topo_IIA_bsu_dom2
IPR018522, TopoIIA_CS
IPR006171, TOPRIM_domain
IPR034160, TOPRIM_GyrB

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00204, DNA_gyraseB, 1 hit
PF00986, DNA_gyraseB_C, 1 hit
PF02518, HATPase_c, 1 hit
PF01751, Toprim, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00387, HATPase_c, 1 hit
SM00433, TOP2c, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54211, SSF54211, 1 hit
SSF55874, SSF55874, 1 hit
SSF56719, SSF56719, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01059, gyrB, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00177, TOPOISOMERASE_II, 1 hit
PS50880, TOPRIM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2R4IQJ4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAAQKKKAQD EYGAASITIL EGLEAVRKRP GMYIGSTGER GLHHLIWEVV
60 70 80 90 100
DNAVDEAMAG YATTVNVVLL EDGGVEVADD GRGIPVATHA SGIPTVDVVM
110 120 130 140 150
TQLHAGGKFD SDAYAISGGL HGVGVSVVNA LSTRLEVEIK RDGYEWSQVY
160 170 180 190 200
EKSEPLGLKQ GAPTKKTGST VRFWADPAVF ETTEYDFETV ARRLQEMAFL
210 220 230 240 250
NKGLTINLTD ERVTQDEVVD EVVSDVAEAP KSASERAAES TAPHKVKSRT
260 270 280 290 300
FHYPGGLVDF VKHINRTKNA IHSSIVDFSG KGTGHEVEIA MQWNAGYSES
310 320 330 340 350
VHTFANTINT HEGGTHEEGF RSALTSVVNK YAKDRKLLKD KDPNLTGDDI
360 370 380 390 400
REGLAAVISV KVSEPQFEGQ TKTKLGNTEV KSFVQKVCNE QLTHWFEANP
410 420 430 440 450
TDAKVVVNKA VSSAQARIAA RKARELVRRK SATDIGGLPG KLADCRSTDP
460 470 480 490 500
RKSELYVVEG DSAGGSAKSG RDSMFQAILP LRGKIINVEK ARIDRVLKNT
510 520 530 540 550
EVQAIITALG TGIHDEFDIG KLRYHKIVLM ADADVDGQHI STLLLTLLFR
560 570 580 590 600
FMRPLIENGH VFLAQPPLYK LKWQRSDPEF AYSDRERDGL LEAGLKAGKK
610 620 630 640 650
INKEDGIQRY KGLGEMDAKE LWETTMDPSV RVLRQVTLDD AAAADELFSI
660 670
LMGEDVDARR SFITRNAKDV RFLDV
Length:675
Mass (Da):74,091
Last modified:June 20, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4559D0D3FDAC8DC1
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
MG995341 Genomic DNA Translation: AVV29662.1
MG995342 Genomic DNA Translation: AVV29663.1
MG995343 Genomic DNA Translation: AVV29664.1
MG995344 Genomic DNA Translation: AVV29665.1
MG995345 Genomic DNA Translation: AVV29666.1
MG995346 Genomic DNA Translation: AVV29667.1
MG995347 Genomic DNA Translation: AVV29668.1
MG995349 Genomic DNA Translation: AVV29670.1
MG995350 Genomic DNA Translation: AVV29671.1
MG995351 Genomic DNA Translation: AVV29672.1
MG995352 Genomic DNA Translation: AVV29673.1
MG995353 Genomic DNA Translation: AVV29674.1
MG995354 Genomic DNA Translation: AVV29675.1
MG995355 Genomic DNA Translation: AVV29676.1
MG995356 Genomic DNA Translation: AVV29677.1
MG995358 Genomic DNA Translation: AVV29679.1
MG995359 Genomic DNA Translation: AVV29680.1
MG995360 Genomic DNA Translation: AVV29681.1
MG995361 Genomic DNA Translation: AVV29682.1
MG995362 Genomic DNA Translation: AVV29683.1
MG995363 Genomic DNA Translation: AVV29684.1
MG995364 Genomic DNA Translation: AVV29685.1
MG995365 Genomic DNA Translation: AVV29686.1
MG995377 Genomic DNA Translation: AVV29698.1
MG995378 Genomic DNA Translation: AVV29699.1
MG995379 Genomic DNA Translation: AVV29700.1
MG995380 Genomic DNA Translation: AVV29701.1
MG995381 Genomic DNA Translation: AVV29702.1
MG995382 Genomic DNA Translation: AVV29703.1
MG995383 Genomic DNA Translation: AVV29704.1
MG995384 Genomic DNA Translation: AVV29705.1
MG995385 Genomic DNA Translation: AVV29706.1
MG995386 Genomic DNA Translation: AVV29707.1
MG995389 Genomic DNA Translation: AVV29710.1
MG995390 Genomic DNA Translation: AVV29711.1
MG995391 Genomic DNA Translation: AVV29712.1
MG995392 Genomic DNA Translation: AVV29713.1
MG995393 Genomic DNA Translation: AVV29714.1
MG995394 Genomic DNA Translation: AVV29715.1
MG995395 Genomic DNA Translation: AVV29716.1
MG995396 Genomic DNA Translation: AVV29717.1
MG995397 Genomic DNA Translation: AVV29718.1
MG995398 Genomic DNA Translation: AVV29719.1
MG995399 Genomic DNA Translation: AVV29720.1
MG995400 Genomic DNA Translation: AVV29721.1
MG995401 Genomic DNA Translation: AVV29722.1
MG995402 Genomic DNA Translation: AVV29723.1
MG995403 Genomic DNA Translation: AVV29724.1
MG995404 Genomic DNA Translation: AVV29725.1
MG995405 Genomic DNA Translation: AVV29726.1
MG995406 Genomic DNA Translation: AVV29727.1
MG995408 Genomic DNA Translation: AVV29729.1
MG995409 Genomic DNA Translation: AVV29730.1
MG995410 Genomic DNA Translation: AVV29731.1
MG995411 Genomic DNA Translation: AVV29732.1
MG995412 Genomic DNA Translation: AVV29733.1
MG995414 Genomic DNA Translation: AVV29735.1
MG995415 Genomic DNA Translation: AVV29736.1
CP046529 Genomic DNA Translation: QGV19780.1
QSXJ01000556 Genomic DNA Translation: REM68059.1
SRLJ01000036 Genomic DNA Translation: TGD73717.1
SRLK01000036 Genomic DNA Translation: TGD90200.1
VOOQ01000466 Genomic DNA Translation: TXB92648.1

NCBI Reference Sequences

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RefSeqi
WP_003917863.1, NZ_WUJD01000001.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
45423962

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MG995341 Genomic DNA Translation: AVV29662.1
MG995342 Genomic DNA Translation: AVV29663.1
MG995343 Genomic DNA Translation: AVV29664.1
MG995344 Genomic DNA Translation: AVV29665.1
MG995345 Genomic DNA Translation: AVV29666.1
MG995346 Genomic DNA Translation: AVV29667.1
MG995347 Genomic DNA Translation: AVV29668.1
MG995349 Genomic DNA Translation: AVV29670.1
MG995350 Genomic DNA Translation: AVV29671.1
MG995351 Genomic DNA Translation: AVV29672.1
MG995352 Genomic DNA Translation: AVV29673.1
MG995353 Genomic DNA Translation: AVV29674.1
MG995354 Genomic DNA Translation: AVV29675.1
MG995355 Genomic DNA Translation: AVV29676.1
MG995356 Genomic DNA Translation: AVV29677.1
MG995358 Genomic DNA Translation: AVV29679.1
MG995359 Genomic DNA Translation: AVV29680.1
MG995360 Genomic DNA Translation: AVV29681.1
MG995361 Genomic DNA Translation: AVV29682.1
MG995362 Genomic DNA Translation: AVV29683.1
MG995363 Genomic DNA Translation: AVV29684.1
MG995364 Genomic DNA Translation: AVV29685.1
MG995365 Genomic DNA Translation: AVV29686.1
MG995377 Genomic DNA Translation: AVV29698.1
MG995378 Genomic DNA Translation: AVV29699.1
MG995379 Genomic DNA Translation: AVV29700.1
MG995380 Genomic DNA Translation: AVV29701.1
MG995381 Genomic DNA Translation: AVV29702.1
MG995382 Genomic DNA Translation: AVV29703.1
MG995383 Genomic DNA Translation: AVV29704.1
MG995384 Genomic DNA Translation: AVV29705.1
MG995385 Genomic DNA Translation: AVV29706.1
MG995386 Genomic DNA Translation: AVV29707.1
MG995389 Genomic DNA Translation: AVV29710.1
MG995390 Genomic DNA Translation: AVV29711.1
MG995391 Genomic DNA Translation: AVV29712.1
MG995392 Genomic DNA Translation: AVV29713.1
MG995393 Genomic DNA Translation: AVV29714.1
MG995394 Genomic DNA Translation: AVV29715.1
MG995395 Genomic DNA Translation: AVV29716.1
MG995396 Genomic DNA Translation: AVV29717.1
MG995397 Genomic DNA Translation: AVV29718.1
MG995398 Genomic DNA Translation: AVV29719.1
MG995399 Genomic DNA Translation: AVV29720.1
MG995400 Genomic DNA Translation: AVV29721.1
MG995401 Genomic DNA Translation: AVV29722.1
MG995402 Genomic DNA Translation: AVV29723.1
MG995403 Genomic DNA Translation: AVV29724.1
MG995404 Genomic DNA Translation: AVV29725.1
MG995405 Genomic DNA Translation: AVV29726.1
MG995406 Genomic DNA Translation: AVV29727.1
MG995408 Genomic DNA Translation: AVV29729.1
MG995409 Genomic DNA Translation: AVV29730.1
MG995410 Genomic DNA Translation: AVV29731.1
MG995411 Genomic DNA Translation: AVV29732.1
MG995412 Genomic DNA Translation: AVV29733.1
MG995414 Genomic DNA Translation: AVV29735.1
MG995415 Genomic DNA Translation: AVV29736.1
CP046529 Genomic DNA Translation: QGV19780.1
QSXJ01000556 Genomic DNA Translation: REM68059.1
SRLJ01000036 Genomic DNA Translation: TGD73717.1
SRLK01000036 Genomic DNA Translation: TGD90200.1
VOOQ01000466 Genomic DNA Translation: TXB92648.1
RefSeqiWP_003917863.1, NZ_WUJD01000001.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

GeneIDi45423962

Family and domain databases

CDDicd03366, TOPRIM_TopoIIA_GyrB, 1 hit
Gene3Di3.30.230.10, 1 hit
3.30.565.10, 1 hit
3.40.50.670, 1 hit
HAMAPiMF_01898, GyrB, 1 hit
InterProiView protein in InterPro
IPR002288, DNA_gyrase_B_C
IPR011557, GyrB
IPR003594, HATPase_C
IPR036890, HATPase_C_sf
IPR020568, Ribosomal_S5_D2-typ_fold
IPR014721, Ribosomal_S5_D2-typ_fold_subgr
IPR001241, Topo_IIA
IPR013760, Topo_IIA-like_dom_sf
IPR013759, Topo_IIA_B_C
IPR013506, Topo_IIA_bsu_dom2
IPR018522, TopoIIA_CS
IPR006171, TOPRIM_domain
IPR034160, TOPRIM_GyrB
PfamiView protein in Pfam
PF00204, DNA_gyraseB, 1 hit
PF00986, DNA_gyraseB_C, 1 hit
PF02518, HATPase_c, 1 hit
PF01751, Toprim, 1 hit
SMARTiView protein in SMART
SM00387, HATPase_c, 1 hit
SM00433, TOP2c, 1 hit
SUPFAMiSSF54211, SSF54211, 1 hit
SSF55874, SSF55874, 1 hit
SSF56719, SSF56719, 1 hit
TIGRFAMsiTIGR01059, gyrB, 1 hit
PROSITEiView protein in PROSITE
PS00177, TOPOISOMERASE_II, 1 hit
PS50880, TOPRIM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2R4IQJ4_MYCTX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2R4IQJ4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 20, 2018
Last sequence update: June 20, 2018
Last modified: February 10, 2021
This is version 23 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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