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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Methylotenera sp.
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.Imported

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotation, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
ORF Names:CTY32_03510Imported
OrganismiMethylotenera sp.Imported
Taxonomic identifieri2051956 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesMethylophilaceaeMethylotenera

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

CytoplasmUniRule annotation

Interactioni

Subunit structurei

Monomer.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini3 – 86Arg_tRNA_synt_NInterPro annotationAdd BLAST84
Domaini435 – 552DALR_1InterPro annotationAdd BLAST118

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi123 – 133"HIGH" regionUniRule annotationAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2P5LCZ7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKTHLTQLLT TAAKSIAPEI TDLTIILERP KSADHGDFAT NLALVLAKPL
60 70 80 90 100
KQNPRAIATQ IIEALPVSEY IAKTEIAGAG FINFFLSPQS KQVVIKDIFN
110 120 130 140 150
AAEQYGRNNN GNQQKVQVEF VSANPTGPLH VGHGRGAAVG DCLARLLDAN
160 170 180 190 200
GWNVTREFYY NDAGAQIDNL TISVLARCKG ISTEHESFPE NGYRGEYIND
210 220 230 240 250
IAAAFLAKHT VVADDIEVTA SGDINDLNSI RTFSVAYLRH EQDLDLKAFQ
260 270 280 290 300
IKFDVFSLES ALYTTGKVEQ TVQALIKSGH TYEENDALWL KTTDFGDDKD
310 320 330 340 350
RVMRKTDGGY TYFVPDVAYH TDKWNRGFVR VINEQGADHH STITRVRAGL
360 370 380 390 400
QALDIGIPKG WPDYVLHQMV TVMRGGEEVK LSKRAGSYVT LRDLIEEVGC
410 420 430 440 450
DATRYFLAAR RADSQLVFDI DLARSQSNDN PVYYIQYAHA RICSVLSQWG
460 470 480 490 500
GDISSLANAN LNPLVTAHET ALMQRLSEYP EVVANAATEL APHVVANYLK
510 520 530 540 550
ELASDLHSYY NEYKFLIEDE SLKLARLSLI SATQQVLKNG LDLLGVAAKE

RM
Length:552
Mass (Da):61,163
Last modified:May 23, 2018 - v1
Checksum:iF1DF992E4FCDD55C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
PERH01000013 Genomic DNA Translation: PPC96950.1

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
PERH01000013 Genomic DNA Translation: PPC96950.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001412 aa-tRNA-synth_I_CS
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
PROSITEiView protein in PROSITE
PS00178 AA_TRNA_LIGASE_I, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2P5LCZ7_9PROT
AccessioniPrimary (citable) accession number: A0A2P5LCZ7
Entry historyiIntegrated into UniProtKB/TrEMBL: May 23, 2018
Last sequence update: May 23, 2018
Last modified: July 18, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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