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Protein
Submitted name:

ATP-binding cassette subfamily B member 11

Gene

Abcb11

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi455 – 462ATPPROSITE-ProRule annotation8
Nucleotide bindingi1113 – 1120ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandATP-bindingPROSITE-ProRule annotationImported, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
ATP-binding cassette subfamily B member 11Imported
Gene namesi
Name:Abcb11Imported
Synonyms:BsepImported, SpgpImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei59 – 86HelicalSequence analysisAdd BLAST28
Transmembranei144 – 166HelicalSequence analysisAdd BLAST23
Transmembranei242 – 264HelicalSequence analysisAdd BLAST23
Transmembranei321 – 342HelicalSequence analysisAdd BLAST22
Transmembranei354 – 374HelicalSequence analysisAdd BLAST21
Transmembranei752 – 775HelicalSequence analysisAdd BLAST24
Transmembranei795 – 821HelicalSequence analysisAdd BLAST27
Transmembranei886 – 911HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

SMRiA0A2P1EA62
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini63 – 385ABC transmembrane type-1InterPro annotationAdd BLAST323
Domaini420 – 656ABC transporterInterPro annotationAdd BLAST237
Domaini756 – 1043ABC transmembrane type-1InterPro annotationAdd BLAST288
Domaini1078 – 1316ABC transporterInterPro annotationAdd BLAST239

Keywords - Domaini

RepeatSAAS annotation, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Gene3Di1.20.1560.10, 2 hits
InterProiView protein in InterPro
IPR003593 AAA+_ATPase
IPR011527 ABC1_TM_dom
IPR036640 ABC1_TM_sf
IPR003439 ABC_transporter-like
IPR017871 ABC_transporter_CS
IPR030278 BSEP
IPR027417 P-loop_NTPase
PANTHERiPTHR24221:SF165 PTHR24221:SF165, 1 hit
PfamiView protein in Pfam
PF00664 ABC_membrane, 2 hits
PF00005 ABC_tran, 2 hits
SMARTiView protein in SMART
SM00382 AAA, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
SSF90123 SSF90123, 3 hits
PROSITEiView protein in PROSITE
PS50929 ABC_TM1F, 2 hits
PS00211 ABC_TRANSPORTER_1, 1 hit
PS50893 ABC_TRANSPORTER_2, 2 hits

Sequencei

Sequence statusi: Complete.

A0A2P1EA62-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDSVILRSV KKFGEENHAF ESDGSHNNDK KSRLQDKMKE GDIRVGFFEL
60 70 80 90 100
FRFSSSKDIW LMLMGGVCAL LHGMAQPGIL IIFGIMTDIF IKYDIERQEL
110 120 130 140 150
EIPGKACVNN TIVWINSSFH QNMTNGTVCG LVDIESEMIK FSGIYAGVGM
160 170 180 190 200
TVLILGYFQI RLWVITGARQ IRRMRKIYFR RIMRMEIGWF DCTSVGELNS
210 220 230 240 250
RFADDIEKIN DAIADQLAHF LQRMSTAMCG LLLGFYRGWK LTLVILAVSP
260 270 280 290 300
LIGIGAAVIG LSIAKFTELE LKAYAKAGSI ADEVLSSIRT VAAFGGENKE
310 320 330 340 350
VERYEKNLVF AQRWGIWKGM VMGFFTGYMW CLIFFCYALA FWYGSTLVLD
360 370 380 390 400
EEEYTPGTLV QIFLCVILAA MNIGHASSCL EIFSTGCSAA TNIFQTIDRQ
410 420 430 440 450
PVIDCMSGDG YKLDRIKGEI EFHNVTFHYP SRPDVKILDN LSMVIKPGET
460 470 480 490 500
TALVGSSGAG KSTALQLIQR FYDPCEGMVT LDGHDIRSLN IRWLRDQIGI
510 520 530 540 550
VEQEPVLFST TIAENIRFGR EDATMEDIVQ AAKDANAYNF IMALPQQFDT
560 570 580 590 600
LVGEGGGQMS GGQKQRVAIA RALIRNPKIL LLDMATSALD NESEARVQEA
610 620 630 640 650
LNKIQHGHTI ISVAHRLSTV RAADVIIGFE HGVAVERGTH EELLERKGVY
660 670 680 690 700
FMLVTLQSQG DNAHKETSIM GKDATEGGTL ERTFSRGSYR DSLRASIRQR
710 720 730 740 750
SKSQLSLLTH DPPLAVADHK SSYKDSKDND VLVEEVEPAP VRRILKYNIP
760 770 780 790 800
EWHYILVGSL SAAINGAVTP IYSLLFSQLL GTFSLLDKEQ QRSEIHSMCL
810 820 830 840 850
FFVILGCVSI FTQFLQGYTF AKSGELLTKR LRKFGFKAML GQDIGWFDDL
860 870 880 890 900
RNNPGVLTTR LATDASQVQG ATGSQVGMMV NSFTNIIAAL LIAFFFSWKL
910 920 930 940 950
SLIITIFFPF LALSGAVQTK MLTGFASQDK QALEKAGQIT SEALSNIRTV
960 970 980 990 1000
AGIGVEGRFI KAFEVELQTS YKTAVRKANI YGLCFAFSQG IAFLANSAAY
1010 1020 1030 1040 1050
RYGGYLIAYE GLGFSHVFRV VSSVALSATA VGRTFSYTPS YAKAKISAAR
1060 1070 1080 1090 1100
FFQLLDRKPP INVYSEAGEK WDNFQGKIDF IDCKFTYPSR PDIQVLNGLS
1110 1120 1130 1140 1150
VSVNPGQTLA FVGSSGCGKS TSIQLLERFY DPDQGTVMID GHDSKKVNIQ
1160 1170 1180 1190 1200
FLRSNIGIVS QEPVLFDCSI MDNIKYGDNT KEISVERAIA AAKQAQLHDF
1210 1220 1230 1240 1250
VMSLPEKYET NVGIQGSQLS RGEKQRIAIA RAIVRDPKIL LLDEATSALD
1260 1270 1280 1290 1300
TESEKTVQTA LDKAREGRTC IVIAHRLSTI QNSDIIAVVS QGVVIEKGTH
1310 1320
EKLMAQKGAY YKLVITGAPI S
Length:1,321
Mass (Da):146,258
Last modified:May 23, 2018 - v1
Checksum:i5443F4EF7B9FB1F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
MG254896 mRNA Translation: AVL26215.1
RefSeqiNP_113948.1, NM_031760.1
UniGeneiRn.14539

Genome annotation databases

GeneIDi83569

Similar proteinsi

Entry informationi

Entry nameiA0A2P1EA62_RAT
AccessioniPrimary (citable) accession number: A0A2P1EA62
Entry historyiIntegrated into UniProtKB/TrEMBL: May 23, 2018
Last sequence update: May 23, 2018
Last modified: July 18, 2018
This is version 3 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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