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Protein
Submitted name:

Transmembrane and coiled-coil domains 3

Gene

TMCO3

Organism
Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Submitted name:
Transmembrane and coiled-coil domains 3Imported
Gene namesi
Name:TMCO3Imported
OrganismiSaimiri boliviensis boliviensis (Bolivian squirrel monkey)Imported
Taxonomic identifieri39432 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeSaimiriinaeSaimiri
Proteomesi
  • UP000233220 Componenti: Whole Genome Shotgun Assembly

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei325 – 347HelicalSequence analysisAdd BLAST23
Transmembranei367 – 385HelicalSequence analysisAdd BLAST19
Transmembranei397 – 416HelicalSequence analysisAdd BLAST20
Transmembranei422 – 441HelicalSequence analysisAdd BLAST20
Transmembranei453 – 475HelicalSequence analysisAdd BLAST23
Transmembranei495 – 518HelicalSequence analysisAdd BLAST24
Transmembranei539 – 559HelicalSequence analysisAdd BLAST21
Transmembranei595 – 613HelicalSequence analysisAdd BLAST19
Transmembranei620 – 643HelicalSequence analysisAdd BLAST24
Transmembranei649 – 670HelicalSequence analysisAdd BLAST22
Transmembranei682 – 701HelicalSequence analysisAdd BLAST20

Keywords - Cellular componenti

Membrane

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini315 – 701Na_H_ExchangerInterPro annotationAdd BLAST387

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili102 – 122Sequence analysisAdd BLAST21
Coiled coili166 – 200Sequence analysisAdd BLAST35
Coiled coili218 – 245Sequence analysisAdd BLAST28

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00390000001394

Family and domain databases

Gene3Di1.20.1530.20, 1 hit
InterProiView protein in InterPro
IPR006153 Cation/H_exchanger
IPR038770 Na+/solute_symporter_sf
PfamiView protein in Pfam
PF00999 Na_H_Exchanger, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A2K6TPF4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNYYSTICDS NSFSAENVYL KCEVSKAETC GLLCPALQTW IMKGLGRSFF
60 70 80 90 100
WVLFPVLPWA TQAVEHEEVA QRVIKLHRGR GAAATQSRQW VRDSCRKLTG
110 120 130 140 150
LLRQKNAVLN KLKNAIGAVE RDVGLSGEEK LFQVHTFEIF QKELNESENS
160 170 180 190 200
VFQAIYGLQR ALQGDYKDVV NMKESSRQRL EALREAAIKE ETEYVELLAA
210 220 230 240 250
EKHQAEALKN MQHQNKSLSM LDEILEDVRK AADRLEEEIE EHAFDDNKSV
260 270 280 290 300
KGVNFEAVLR VEEEEANSKQ NMTKREVEGD LGLSMLIDSQ NNQYILTKPR
310 320 330 340 350
DSTIPRADHH FIKDIVTIGM LSLPCGWLCT AIGLPTMFGY IICGVLLGPS
360 370 380 390 400
GLNSIKSIVQ VETLGEFGVF FTLFLVGLEF SPEKLRKVWK ISLQGPCYMT
410 420 430 440 450
LLTIAFGLLW GHLLRIKPTQ SVFISTCLSL SSTPLVSRFL VGSARGDKEG
460 470 480 490 500
DIDYSTVLLG MLVTQDVQLG LFMAVMPTLI QAGTSASSSI VMEVLRILVL
510 520 530 540 550
IGQILFSLAA VFLLCLVIKK YLIGPYYRKL HVESKGNKEI LILGISAFIF
560 570 580 590 600
LMLTVTELLD VSMELGCFLA GALVSSQGPV VTEEIAASIE PIRDFLAIIF
610 620 630 640 650
FASIGLHVFP TFVAYELTVL VFLTLSVVVM KFLLAALVLS LTLPRSSQYI
660 670 680 690 700
KWIVSAGLAQ VSEFSFVLGS RARRAGIISR EVYLLILSVT TLSLLLAPVL
710
WRAAITRCVP RPERRSSL
Length:718
Mass (Da):79,944
Last modified:March 28, 2018 - v1
Checksum:iE4F3471DE2F35430
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2K6TPE4A0A2K6TPE4_SAIBB
Transmembrane and coiled-coil domai...
TMCO3
677Annotation score:

Sequence databases

RefSeqiXP_003928312.2, XM_003928263.2

Genome annotation databases

EnsembliENSSBOT00000038379; ENSSBOP00000021541; ENSSBOG00000027320
GeneIDi101050655
KEGGisbq:101050655

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_003928312.2, XM_003928263.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSSBOT00000038379; ENSSBOP00000021541; ENSSBOG00000027320
GeneIDi101050655
KEGGisbq:101050655

Organism-specific databases

CTDi55002

Phylogenomic databases

GeneTreeiENSGT00390000001394

Family and domain databases

Gene3Di1.20.1530.20, 1 hit
InterProiView protein in InterPro
IPR006153 Cation/H_exchanger
IPR038770 Na+/solute_symporter_sf
PfamiView protein in Pfam
PF00999 Na_H_Exchanger, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2K6TPF4_SAIBB
AccessioniPrimary (citable) accession number: A0A2K6TPF4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: July 18, 2018
This is version 5 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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