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Entry version 16 (19 Jan 2022)
Sequence version 1 (28 Mar 2018)
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Protein
Submitted name:

Spectrin repeat containing nuclear envelope protein 1

Gene

SYNE1

Organism
Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActin-bindingARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Spectrin repeat containing nuclear envelope protein 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SYNE1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaimiri boliviensis boliviensis (Bolivian squirrel monkey)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri39432 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeSaimiriinaeSaimiri
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000233220 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 8699CytoplasmicPROSITE-ProRule annotationAdd BLAST8699
Topological domaini8721 – 8750Perinuclear spacePROSITE-ProRule annotationAdd BLAST30

Keywords - Cellular componenti

Membrane, NucleusARBA annotation

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini27 – 141Calponin-homology (CH)InterPro annotationAdd BLAST115
Domaini185 – 290Calponin-homology (CH)InterPro annotationAdd BLAST106
Domaini8691 – 8750KASHInterPro annotationAdd BLAST60

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1299 – 1319DisorderedSequence analysisAdd BLAST21
Regioni5789 – 5816DisorderedSequence analysisAdd BLAST28
Regioni8174 – 8211DisorderedSequence analysisAdd BLAST38
Regioni8624 – 8686DisorderedSequence analysisAdd BLAST63

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili334 – 354Sequence analysisAdd BLAST21
Coiled coili629 – 656Sequence analysisAdd BLAST28
Coiled coili782 – 802Sequence analysisAdd BLAST21
Coiled coili824 – 844Sequence analysisAdd BLAST21
Coiled coili936 – 956Sequence analysisAdd BLAST21
Coiled coili1321 – 1348Sequence analysisAdd BLAST28
Coiled coili1420 – 1454Sequence analysisAdd BLAST35
Coiled coili1561 – 1581Sequence analysisAdd BLAST21
Coiled coili1633 – 1653Sequence analysisAdd BLAST21
Coiled coili1909 – 1929Sequence analysisAdd BLAST21
Coiled coili1987 – 2014Sequence analysisAdd BLAST28
Coiled coili2021 – 2041Sequence analysisAdd BLAST21
Coiled coili2091 – 2111Sequence analysisAdd BLAST21
Coiled coili2175 – 2202Sequence analysisAdd BLAST28
Coiled coili2237 – 2271Sequence analysisAdd BLAST35
Coiled coili2349 – 2383Sequence analysisAdd BLAST35
Coiled coili2489 – 2509Sequence analysisAdd BLAST21
Coiled coili2783 – 2810Sequence analysisAdd BLAST28
Coiled coili2969 – 2989Sequence analysisAdd BLAST21
Coiled coili3168 – 3188Sequence analysisAdd BLAST21
Coiled coili3412 – 3439Sequence analysisAdd BLAST28
Coiled coili3473 – 3493Sequence analysisAdd BLAST21
Coiled coili3607 – 3627Sequence analysisAdd BLAST21
Coiled coili3675 – 3695Sequence analysisAdd BLAST21
Coiled coili3768 – 3788Sequence analysisAdd BLAST21
Coiled coili4075 – 4095Sequence analysisAdd BLAST21
Coiled coili4204 – 4234Sequence analysisAdd BLAST31
Coiled coili4702 – 4736Sequence analysisAdd BLAST35
Coiled coili4780 – 4800Sequence analysisAdd BLAST21
Coiled coili4997 – 5017Sequence analysisAdd BLAST21
Coiled coili5081 – 5101Sequence analysisAdd BLAST21
Coiled coili5286 – 5313Sequence analysisAdd BLAST28
Coiled coili5339 – 5359Sequence analysisAdd BLAST21
Coiled coili5398 – 5418Sequence analysisAdd BLAST21
Coiled coili5434 – 5461Sequence analysisAdd BLAST28
Coiled coili5528 – 5548Sequence analysisAdd BLAST21
Coiled coili5556 – 5583Sequence analysisAdd BLAST28
Coiled coili5670 – 5690Sequence analysisAdd BLAST21
Coiled coili5701 – 5738Sequence analysisAdd BLAST38
Coiled coili5933 – 5953Sequence analysisAdd BLAST21
Coiled coili5988 – 6015Sequence analysisAdd BLAST28
Coiled coili6092 – 6119Sequence analysisAdd BLAST28
Coiled coili6157 – 6184Sequence analysisAdd BLAST28
Coiled coili6456 – 6476Sequence analysisAdd BLAST21
Coiled coili6514 – 6538Sequence analysisAdd BLAST25
Coiled coili6987 – 7021Sequence analysisAdd BLAST35
Coiled coili7093 – 7123Sequence analysisAdd BLAST31
Coiled coili7742 – 7769Sequence analysisAdd BLAST28
Coiled coili7849 – 7869Sequence analysisAdd BLAST21
Coiled coili8421 – 8441Sequence analysisAdd BLAST21
Coiled coili8595 – 8619Sequence analysisAdd BLAST25

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi5792 – 5816Polar residuesSequence analysisAdd BLAST25
Compositional biasi8174 – 8197Polar residuesSequence analysisAdd BLAST24
Compositional biasi8624 – 8684Polar residuesSequence analysisAdd BLAST61

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the nesprin family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysisARBA annotation, RepeatARBA annotation, Transmembrane, Transmembrane helixARBA annotation

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000154481

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00014, CH, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.418.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001589, Actinin_actin-bd_CS
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR012315, KASH
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00307, CH, 2 hits
PF10541, KASH, 1 hit
PF00435, Spectrin, 12 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00033, CH, 2 hits
SM01249, KASH, 1 hit
SM00150, SPEC, 42 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47576, SSF47576, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00019, ACTININ_1, 1 hit
PS00020, ACTININ_2, 1 hit
PS50021, CH, 2 hits
PS51049, KASH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

A0A2K6TBN9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
HDIHRGRKRC QGKTHKNFFF LLDEQEIVQK RTFTKWINSH LAKRKPPMVV
60 70 80 90 100
DDLFEDMKDG VKLLALLEVL SGQKLPCEQG RRMKRIHAVA NIGTALKFLE
110 120 130 140 150
GRKSMHRGSP IKLVNINSTD IADGRPSIVL GLMWTIILYF QIEELTSNLP
160 170 180 190 200
QLQSLSSSAS SVDSLVSSET PSPPSKRKVT TKIQGNAKKA LLKWVQYTAG
210 220 230 240 250
KQIGIEVKDF GKSWRSGVAF HSVIHAIRPE LVDLEKVKGR PNRENLEDAF
260 270 280 290 300
TIAETELGIP RLLDPEDVDV DKPDEKSIMT YVAQFLKHYP DIHNAGTDGQ
310 320 330 340 350
EDDEILPGFP SFANSIQNFK REDRLILKEM KVWIEQFERD LTRAQMVESN
360 370 380 390 400
LQDKYQSFKH FRVQYEMKRK QIEHLIQPLH RDGKLSLDQA LVKQSWDRVS
410 420 430 440 450
SRLCDWHIQL DKSLPAPLGT IGAWLYRAEV ALREEITIQQ VHEETANTIQ
460 470 480 490 500
RKLEQHKDLL QNTDAHKRAF HEIYRTRSVN GIPVPPDQLE DMAERFHFVS
510 520 530 540 550
STSELHLMKM EFLELKYRLL SLLVLAESKL KSWIIKYGRR ESVEQLLQNY
560 570 580 590 600
VSFIENSKFF EQYEVTYQIL KQTAEMYIKA DGSVEEAENV MKFMNETTAQ
610 620 630 640 650
WRNLSVEVRS VRSMLEEVIS NWDRYGNTVA SLQAWLEDAE KMLNQSENAK
660 670 680 690 700
KDFFRNLPHW IQQHTAMNDA GNFLIETCNE MVSRDLKQQL LLLNGRWREL
710 720 730 740 750
FMEVKQYAQA DEMDRMKKEY TDCVVTLSAF ATESLKKLSE PLEVSFMNVK
760 770 780 790 800
LLIQDLEDIE QRVPVMDAQY KIITKTAHLI TKESSQEEGK EMLATMSKLK
810 820 830 840 850
EQLTKVKECY SPLLYECQQL LIPLEELEKQ MTSFYDSLEK INEIITVLEH
860 870 880 890 900
EAQSSALFKQ KHQELLACQD NSKKTLTLIE KGSQSVQKFV TLSNVLKHFD
910 920 930 940 950
QTRLQRQIAD VHVAFQIMVK KTGDWKKHVE TNSRLMKKFE ESRAELEKVL
960 970 980 990 1000
RIAQEGLEEK GDPEVLLRRH TEFFSQLDQR VLNAFLKACD ELTDILPEQE
1010 1020 1030 1040 1050
QQGLQEAVRK LHKQWKDLQG EAPYHLLHLK IDVEKNRFLA SVEECRAELD
1060 1070 1080 1090 1100
RETKLMPQEG SEKIIKEHRV FFSDKGPHHL CEKRLQLIEE LCVKLPVRDP
1110 1120 1130 1140 1150
VRDTPGTCHA TLKELRAAID STYRKLMEDP DKWKDYMSRF SEFSSWISTK
1160 1170 1180 1190 1200
ETQLKGIKGE AINTANHGEV KCAVEEIRNG IAKRGETLSW LKSRLKVLTE
1210 1220 1230 1240 1250
VSSENEAQKQ GDELATLSSS FKGLSTLLSE VEKMVSNFGD CVQYKEIVKN
1260 1270 1280 1290 1300
SLEELISGSK EAQEQAEKIL DTENLFEAQQ LLLHHQQKTK RISAKKKDVQ
1310 1320 1330 1340 1350
QQMAQAQQGE GGLPDRGREE LRKLESTLDG LERSRERQER RIQVTLRKWE
1360 1370 1380 1390 1400
RFETNKETVV RYLFQTGSSH ERFLSFSSLE SLSSELEQTK EFSKRTESIA
1410 1420 1430 1440 1450
VQAENLVKEA SEIPLGPQNK QLLQQQAKSI KEQVKKLEDT LEEDIKTMEM
1460 1470 1480 1490 1500
VKTKWDHFGS NFETLSAWIT EKEKELNDLE TSSSAMDMQI SQIKVTIQEI
1510 1520 1530 1540 1550
ESKLSSIIGL EEEAQSFAQF VTTGESARIK AKLTQIRRYW EELREHAQCL
1560 1570 1580 1590 1600
EGTILGHLSQ QQKFEANLRK IQQSVSEFED KLAVPIKICA SATETYKVLQ
1610 1620 1630 1640 1650
EHMDLCQALE SLSSPITAFS ASARKVVNRD FCVQEAAALQ QQYEGTLRKA
1660 1670 1680 1690 1700
KERQTVLENL LAHWQRMEKE LSSFLTWLER CEAIASSPEM DISADRVKVE
1710 1720 1730 1740 1750
SELQLIQALQ NEVVSQASFY SKLLQLKEAL FSVASKEDVK MLKLHLEQLD
1760 1770 1780 1790 1800
ERWRDLPQII SKRIRFLQSV VAEHQQFDEL LLSFSIWIKL FLSELQATSE
1810 1820 1830 1840 1850
ISIMDHQVAL TRHKDHTADV ESKKGELQSL QGHLAKLGSL GRAEDLHLLQ
1860 1870 1880 1890 1900
GKAEDCFQLF EEASQVVERR QLALSHLAEF LQSHASLSSV LHQLRQTVEA
1910 1920 1930 1940 1950
TNSMNKNQSD LIEKNLNDAI QDAKALESTA VSLDGILSKA QYHLKSGSSE
1960 1970 1980 1990 2000
QRTSCRATVD QLFGELERIQ NLLGTKQSEA DALAVLKKAF QDQKDELLKS
2010 2020 2030 2040 2050
IENIEERTDK ERLKEPTRQA LQQRLRVFNQ LEDELNSHEH ELCWLKDKAK
2060 2070 2080 2090 2100
QIAQKDVAFA PEVDREINCL EVTWNDTKRL IHENQGQCCG LIDLMREYQN
2110 2120 2130 2140 2150
LKSAVSKVLE NATSVIVTRT TIKDQEDLKW AFSKHETARN KMNYKQNDLD
2160 2170 2180 2190 2200
NFTSKGKHLL SELKKIHSSD FSLMKTDMES TVDKWLDVAE KLEENMDRLR
2210 2220 2230 2240 2250
VSLSIWDDVL SSKDEIEGWS NNSVPQMAES ISNLSNHLRA EELLKEFEAE
2260 2270 2280 2290 2300
VKNKALRLEE LHSKVNDLKK LTKNPETPPD LRFIEADLRQ KLEHAKEITE
2310 2320 2330 2340 2350
VAKGTLKDFT AQSTQVEKFI NDVTAWLAKV EESLTNCAQT ETCEGLKKVK
2360 2370 2380 2390 2400
DIQKELQSQQ SNISSTQENL NSLCRKYHSA ELESLGRAMT GLIKKHEAVS
2410 2420 2430 2440 2450
QLCSKTQASL QDSLEKHFSE SMQEFREWFL GAKSAAKESS DRTGDSKVLE
2460 2470 2480 2490 2500
AKLQDLQSVL DSVSDGQSKL DAVTQEGQTL YAHLSKQIVS SIQEQITKAN
2510 2520 2530 2540 2550
EEFQAFLKQC LKDKQALQDC ASELGSFEDQ HRKLNSWIRE MEERLNTENL
2560 2570 2580 2590 2600
GESKQHIPEK KNEVHKVEMF LGELLAARES LDKLSQRGQL LSEEGHGAGQ
2610 2620 2630 2640 2650
EGRLCSQLLT SHQNLLRMTK EKLRSCQVAL QEHEALEEAL KSMWSWVKAI
2660 2670 2680 2690 2700
QERLACAEST LGSKDTLEKR LSQIQDILLM KGEGDVKLNM AIGKGEQALR
2710 2720 2730 2740 2750
SSNKEGQRVI QTQLETLKEV WADIMSSSVH AQSTLESVIS QWNDYLERKN
2760 2770 2780 2790 2800
QLEQWMESVD QKVEHPLQPQ PGLKEKFALL DHLQSILSEA EDHSRALHRL
2810 2820 2830 2840 2850
NAKSRELYEK TEDESFKDTT QEELKTQFTD IMTVAKEKMR KVEEIVKDHL
2860 2870 2880 2890 2900
MYLDAVQEFT DWLHSAKEEL HRWSDMSGDS SATQKKLSKI KELIDSREIG
2910 2920 2930 2940 2950
ASRLSRVELL APEVKQNTTA SGCELMHTEM QALRADWKQW EDSVFQTQSR
2960 2970 2980 2990 3000
LEDLVSQMAL SEQEFSGQVA QLEQALEEFS ALLKTWAQQL TLLEGKNTDE
3010 3020 3030 3040 3050
EIVECWHKGQ EILDALQKAE PRTEDLKSQL NELCRFSRDL STYSGKVSGL
3060 3070 3080 3090 3100
IKEYNCLCLQ ASKGCQNKEQ ILQQRFRKAF RDFQQWLVNA KITTAKCFDI
3110 3120 3130 3140 3150
PQNISEVSTS LQKIQEFMSE SENGQHKLNM MLSKGELLST LLDKEKAKGI
3160 3170 3180 3190 3200
QAKVAAAKED WKNFHSSLHQ KESALENLKI QMKDFEVSAE PIQDWLSKTE
3210 3220 3230 3240 3250
KMVQESSNRL YDLPAKRREQ QKLQSVLEEI HCYEPQLNRL KEKAQQLWEG
3260 3270 3280 3290 3300
QAASKSFRHR VSQLSSQYLA LSNLTKEKVS RLDRIVAEHN QFSLGIKELQ
3310 3320 3330 3340 3350
DWMTDAIHML DSYCHPTSDK SVLDSRMLKL EALLSVKQEK EIQMKMIVTR
3360 3370 3380 3390 3400
GESVLQNTSP EGIPTIQQQL QSVKDMWASL LSAAIRCKSQ LEGALSKWTS
3410 3420 3430 3440 3450
YQDDVRQFSG WMDSMEANLN ESERQHAELR DKITMLGKAK LLNEEVLSYS
3460 3470 3480 3490 3500
SLLETIEVKR SGMTEHYVTQ LELQDLQERY RAIQERAKEA VTKSEKLVRL
3510 3520 3530 3540 3550
HQEYQRDLKA FEAWLGQEQE KLDTYSVLEG DAHTHETTLR DLQELQVHCA
3560 3570 3580 3590 3600
EGQALLNSVL HTREDVIPSG IPQAEDRSLE SLRQDWQAYQ HRLSETRTHF
3610 3620 3630 3640 3650
NNIVNKLRLM EQKFQQVEEW LKTAEEKKWH EEVTAYRDEV EEVGARAQEI
3660 3670 3680 3690 3700
LDESHVSSRM GCQATQLTSR YQALLLQVLE QIKFLEEEIQ SLEESESSLS
3710 3720 3730 3740 3750
SYSDWYGSMH KNFKNVATKI DKVDTAMMGK KLKTLEVLLK DMEKGHSLLK
3760 3770 3780 3790 3800
SAREKGERAI KYLEESEADR LRKEIHDHME QLKELTSTVR KEHMTLEKGL
3810 3820 3830 3840 3850
HLAKEFSDKC KALTQWIAEY QEILHVPEEP KMELYEKKAQ LSKYKSLQQM
3860 3870 3880 3890 3900
VLSHEPSVKS VREKGEALLE MVQDVTLKDK IDQLQSDYQD LCSVGKAMME
3910 3920 3930 3940 3950
EIAGFEDRLN NLQMKGDALI GQCADHLQAK LKQNVHAHVQ GTKDSYSAIC
3960 3970 3980 3990 4000
STAQRVYQSL EHELQKHVSR QDTLQQCQAW LSAVQPDLEP SPQPPLSRAE
4010 4020 4030 4040 4050
AVKQVKHFRA LQEQARTYLD LLCSMCDLSN ASVKTTAKDI QQTEQMIEQR
4060 4070 4080 4090 4100
LVQAQNLTQG WEEIKHLKAE LWIYLQDADQ QLQNMKRRHS ELELNIAQNM
4110 4120 4130 4140 4150
VSQVKDFVKK LQSKQASMNT IIEKVNKLTK KEESPEHKEI NHLNDQWLDL
4160 4170 4180 4190 4200
CHQSNNLCLQ REEDLQRTRN YHDCMNVVEV FLEKFTTEWD NLARSDAEST
4210 4220 4230 4240 4250
AVHLEALKKL ALALQERKHA IEDLKDQKQK MIEHLNLDDK ELVKEQTSHL
4260 4270 4280 4290 4300
EQRWFQLEDL IQRKIQVSIT NLEELNVVQS RFQELMEWAE EQQPNIAEAL
4310 4320 4330 4340 4350
KQSPPPEMAQ NLLMDHLAIC SELEAKQMLL KSLIKDADRV MADLGLNERQ
4360 4370 4380 4390 4400
VIQKALSDAQ RHVNCLSDLV GQRRKYLNKA LSEKTQFLMA VFQATSQIQQ
4410 4420 4430 4440 4450
HERKIMFREH ICLLPDDVSK QVKTCKSAQA SLKTYQNEVT GLWAQGRELM
4460 4470 4480 4490 4500
KGVTEQEKGE VLGKLQELQS VYDSVLQKCS HRLQELEKNL VSRKHFKEDF
4510 4520 4530 4540 4550
DKACHWLKQA DIVTFPEINL MNESAELHTQ LAKYQHILEQ SPEYENLLLT
4560 4570 4580 4590 4600
LQRTGQTILP SLNEVDHSYL SEKLNALPQQ FNVIVALAKD KFYKVQEAIL
4610 4620 4630 4640 4650
ARKEYASLIE LTTQSLSELE AQFLGMSKVP TDLAVEEASS LQDGCRAILD
4660 4670 4680 4690 4700
EVVGLGEAVD ELNQKKEGFR STGQPWQPDK MLHLVTLYHR LKRQTEQRVS
4710 4720 4730 4740 4750
LLEDTTSAYQ EHEKMCQQLE RQLKSVKEEQ SKVNEETLPA EEKLKIYHSL
4760 4770 4780 4790 4800
AGSLQDSGIL LKRVAIHLED LAPHLDPLAY EKARNQIQSW QEELKLLTSA
4810 4820 4830 4840 4850
IGETVTECES RMVQSIDFQT EMSRSLEWLR RVKAELSGPV SLDLNLQDIQ
4860 4870 4880 4890 4900
EEIRKIQIHQ EEVQSSLRIM NALSHKEKEK FTKAKELISA DLEHSLAELS
4910 4920 4930 4940 4950
ELDGDIQEAL RTRQATLTEI YSQCQRYYQV FQAANDWLDD AQEMLQLAGN
4960 4970 4980 4990 5000
GLDVESAEEN LKSHMEFFST EDQFHSNLQE LHSLVANLDP LIKPTGKEDL
5010 5020 5030 5040 5050
AQKMASLELR SQRMSQDSCA QVDILQRCAT QWQDYQKARE EVIELMNDTE
5060 5070 5080 5090 5100
KKLSEFSLLK TSSSHEAEEK LSEHKALVSV VNSFHEKIVA LEDKASQLEK
5110 5120 5130 5140 5150
TGNDASKAAL SRSMTTVWQR WTRLRAVAQD QEKILEDAVD EWKGFNNKVK
5160 5170 5180 5190 5200
KATEMIDQLQ DKLPGSSAEK ASKAELLTLL EYHDTFVLEL EQQQLALGML
5210 5220 5230 5240 5250
RQQALSMLQD GALPTPGGEP PLMQEITAMQ DRCLNMQEKV KTNGKLVKQE
5260 5270 5280 5290 5300
LKDREMVETQ INSVKCWVQE TKEYLGNPTI EVDAQLEELQ ILLTEATNHR
5310 5320 5330 5340 5350
QNIEKMAEEQ KDKYLSLYTI LPSELSLQLA EVALDLKIRD QIQDRIKEVE
5360 5370 5380 5390 5400
QSKAMSQELS RQVQKIAKDL TTILTKLKAK TDNLVQAKTD QKVLGEELDD
5410 5420 5430 5440 5450
CNSKLMELDA AVQKFSEQNG QLGKPLVKKI GKLTELHQQT IRQAENRLSK
5460 5470 5480 5490 5500
LNQAASHLEE YNEMLELILK WIEKAKVLAH GNIAWNSASQ LREQYILHQT
5510 5520 5530 5540 5550
LLEESKEIHS DLEVMTEKLH YLTSVYCTEK MSQQVAELGR ETEELQQMIK
5560 5570 5580 5590 5600
IRLQNLQDAA KDMKKFEAEL KKLQVALEQA QATLTSPEVG RLSLKEQLSH
5610 5620 5630 5640 5650
RQHLLSEMES LKPKVQAVQI CQSALRIPED VVASLPLCHA ALRLQEEASR
5660 5670 5680 5690 5700
LQHTAIQQCN IMQAGAVVQY EQYEQEMKHL QQLIEGAHRE IEDKPVATSN
5710 5720 5730 5740 5750
IQELQAQISR HEELAQKIKG YQEQIASLNS KCKMLTMKAK HATMLLTVTE
5760 5770 5780 5790 5800
VEGLAEGTED LDGELLPAPS AHPSVVMMTA GRCHTLLSPV TEESGEEGTN
5810 5820 5830 5840 5850
SEISSPPACR SPSPVANTDA SVNQDIAYYQ ALSAERLQTD AAKIHPSTST
5860 5870 5880 5890 5900
SQEFYEPGLE PSATAKLGDL QRSWETLKNV ISEKQRTLYE ALERQQKYQD
5910 5920 5930 5940 5950
SLQSISTKME AIELKLSESP EPGRSPESQM AEHQALMDEI LMLQDEINEL
5960 5970 5980 5990 6000
QSSLAEELVS ESCEADPAEQ LALQSTLTVL AERMSTIRMK ASGKRQLLEE
6010 6020 6030 6040 6050
KLNDQLEEQR QEQALQRYRC EADELDSWLL STKATLDIAL GTPKEPMDME
6060 6070 6080 6090 6100
AQLVDCQNML VEIEQKVVAL SELSVHNENL LLEGKAHTKD EAEQLAGKLR
6110 6120 6130 6140 6150
RLKGSLLELQ RALHDKQLNM QGTAQEKEES DVDLTATQSP GVQEWLAQAR
6160 6170 6180 6190 6200
TTRTHQRQSS LQQQKELEQE LAEQKSLLRS VASRGEEILI QHSAAETSGG
6210 6220 6230 6240 6250
TGEKPDVLSQ ELGMEGEKSS TEDQMRMKWE SLHQEFSTKQ KLLQNVLEQE
6260 6270 6280 6290 6300
QEQVLYSRPN RLLSGVPLYK GEVPTQDKSA VTSLLDGLNQ AFEEVSSQSG
6310 6320 6330 6340 6350
GTKRQSIHLE QKLYDGVSAT STWLDDVEEH LFVATALLPE ETETCLFNQE
6360 6370 6380 6390 6400
ILAKDIKEMS EEMDKNKHLF SQAFPENGDN RDVIEDTLGC LLGRLSLLDS
6410 6420 6430 6440 6450
VVNQRCHQMK ERLQQILNFQ NDLKVLFTSL ADNKYIILQK LANVFEQPVA
6460 6470 6480 6490 6500
EQIEAIQQAE DGLKELDAGI IELKRRGDKL QIEQPSMQEL SKLQDMYDEL
6510 6520 6530 6540 6550
MMTIGSRRSG LNQNLTLKSQ YERALQDLAD LLETGQEKMA GDQKIIVSSK
6560 6570 6580 6590 6600
EEIQQLLDKH KEYFQGLESH MILTETLFRK IISFAVQKET QFHTEMMAQA
6610 6620 6630 6640 6650
SAVLKRAHKR GVELEYILET WSHLEEDQQE LSRQLEVVES SIPSVGLVEE
6660 6670 6680 6690 6700
NEDRLIDRIT LYQHLKSSLN EYQPKLYQVL DDGKRLLISI SCSDLESQLN
6710 6720 6730 6740 6750
QLGEHWLSNT NKVSKELHRL ETILKHWTRY QSESADLIHW LQSAKDRLEF
6760 6770 6780 6790 6800
WTQQSVTVPQ ELEMVRDHLN AFLEFSKEVD AKSSLKSSVL STGNQLLRLK
6810 6820 6830 6840 6850
KVDTATLRSE LSHIDSQWTD LLTNIPAVQE KLHQLQMDKL PSRHAISEVM
6860 6870 6880 6890 6900
SWISLMENVI QMDEDNIKNS IGYKAIHEYL QKYKGFKIDI NCKQLTVDFV
6910 6920 6930 6940 6950
NQSVLQISSQ DVESKRSDKT DFAEQLGAMN KSWQILQGLV TEKIQLLESL
6960 6970 6980 6990 7000
LESWSEYENN VQCLKTWFET QEKRLKQQHR IGDQASVQNA LKDCQDLEDL
7010 7020 7030 7040 7050
IKAKEKEVEK IEQNGLALIQ NKKEDVSGAV MSTLRELGQT WANLDHMVGQ
7060 7070 7080 7090 7100
LQILLKSVLD QWSNHKAAFD EINSYLMEAR YSLSRFRLLT GSLEAVQVQV
7110 7120 7130 7140 7150
DNLQNLQDDL EKQETSLQKF GSVTNQLLKE CQPPVTETLT NTLKEVNMRW
7160 7170 7180 7190 7200
NNLLEEIAEQ LHSSKALLQL WQRYKDYSKQ CSSTVQQQED RTNELLKAAT
7210 7220 7230 7240 7250
NKDIADDEVA TWIQDCNDLL KGLGTVKDSL FVLHELGEQL KQQVDASAAS
7260 7270 7280 7290 7300
AIQSDQLSLS QHLCALEQAL CKQQTALQAG VLDYETFAKS LEALEAWIVE
7310 7320 7330 7340 7350
AEEILQGQDP SHSSDLSTIQ ERMEELKGQM LKFSSMAPDL DRLNELGYRL
7360 7370 7380 7390 7400
PLNDKEIKRM QNLNRHWSLI SSQTTERFSK LQSFLLQHQT FLEKCETWME
7410 7420 7430 7440 7450
FLVQTEQKLA VEISGNYQHL LEQQRAHELF QAEMFSRQQI LHSIIIDGQR
7460 7470 7480 7490 7500
LLEQGQVDDR DEFNLKLTLL SNQWQGVIRR AQQRRGIIDS QIRQWQRYRE
7510 7520 7530 7540 7550
MAEKLRKWLV EVSYLPMSGL GSVPIPLQQA RTLFDEVQFK EKVFLRQQGS
7560 7570 7580 7590 7600
YILTVEAGKQ LLLSADSGAE AALQAELTEI QEKWKSASMR LEEQKKKLAF
7610 7620 7630 7640 7650
LLKDWEKCEK GIADSLEKLR TFKKKLSQSL PDHHEDLHAE QMRCKELENA
7660 7670 7680 7690 7700
AGSWTDDLTQ LTLLKDTLSA YISADDISIL NERIELLQRQ WEELCHQLSL
7710 7720 7730 7740 7750
RRQQISERLN EWAVFSEKNK ELCEWLTQME SKVSQNGDIL IEEMIEKLKK
7760 7770 7780 7790 7800
DYQEEIAIAQ ENKIQLQQMG ERLAKASHES KASEIEYKLG KVNDRWQHLL
7810 7820 7830 7840 7850
DLIAARVKKL KETLVAVQQL DKNMSILRTW LAHIESELAK PIVYDSCNSE
7860 7870 7880 7890 7900
EIQRKLNEQQ ELQRDIEKHS TGVASVLNLC EVLLHDCDAC ATDAECDSIQ
7910 7920 7930 7940 7950
QATRNLDRRW RNICAMSMER RLKIEETWRL WQKFLDDYSR FEDWLKISER
7960 7970 7980 7990 8000
TAAFPSSSGV IYTVAKEELK KFEAFQRQVH ECLTQLELIN KQYRRLAREN
8010 8020 8030 8040 8050
RTDSACSLKQ MVHEGNQRWD NLQKRVTSIL RRLKHFIGQR EEFETARDSI
8060 8070 8080 8090 8100
LVWLTEMDLQ LTNIEHFSEC DVQAKIKQLK AFQQEISLNH SKIEQIIAQG
8110 8120 8130 8140 8150
EQLIEKSEPL DAAVIEEELD ELRRYCQEVF GRVERYHKKL IRLPLPDDEH
8160 8170 8180 8190 8200
DLSDRELELE DSAALSDLHW QDRSADSVLS PQPSSNPSLS LAQPLRSERS
8210 8220 8230 8240 8250
GRDTPASVDS IPLEWDHDYD LSRDLESAVS RALPSEDEDG QDDKDFYLRG
8260 8270 8280 8290 8300
AVGLSDIMIP ESPEAYVKLT ENAIKNTSGD HSALESQIRQ LGRALDESRF
8310 8320 8330 8340 8350
QIQQTENIIR SKTPTGPELD TSYKGYMKLL GECSGSIDSV KRLEHKLKEE
8360 8370 8380 8390 8400
EESLPGFVNL HSTETQMAGV IDRWELLQAQ ALSKELRMKQ NLQKWQQFNS
8410 8420 8430 8440 8450
DLNSIWAWLG DTEEELEHLQ HLELSTDIQT IELQIKKLKE LQKAVDHRKA
8460 8470 8480 8490 8500
IILSINLCSP EFTQADSKES RDLQDRLSQM NGRWDRVCSL LEEWRGLLQD
8510 8520 8530 8540 8550
ALMQCQGFHE MSHGLLLMLE NIDRRKNEIV PIDPSLDAEV LQDHHKQLMQ
8560 8570 8580 8590 8600
IRHELLESQL RVASLQDMSC QLLVNAEGAD CLEAKEKVHV IGNRLKLLLK
8610 8620 8630 8640 8650
EVSRHIKELE KLLDVSSSQQ DLSSWSSADE LDTSGSVSPT SGRSTPNRQK
8660 8670 8680 8690 8700
TPRGKCSLSQ PGPSVSSPHS RSTKGGSDSS LSEPGPARSG RAFLFRVLRA
8710 8720 8730 8740 8750
ALPLQLLLLL LIGLACLVPM SEEDYSCALS NNFARSFHPM LRYTNGPPPL
Length:8,750
Mass (Da):1,005,151
Last modified:March 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBA85AB51663F854B
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2K6TBH1A0A2K6TBH1_SAIBB
Spectrin repeat containing nuclear ...
SYNE1
8,797Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2K6TBL2A0A2K6TBL2_SAIBB
Spectrin repeat containing nuclear ...
SYNE1
8,797Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2K6TBX0A0A2K6TBX0_SAIBB
Spectrin repeat containing nuclear ...
SYNE1
8,405Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2K6TC18A0A2K6TC18_SAIBB
Spectrin repeat containing nuclear ...
SYNE1
8,371Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2K6TC31A0A2K6TC31_SAIBB
Spectrin repeat containing nuclear ...
SYNE1
975Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2K6TC53A0A2K6TC53_SAIBB
Spectrin repeat containing nuclear ...
SYNE1
1,703Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2K6TC77A0A2K6TC77_SAIBB
Spectrin repeat containing nuclear ...
SYNE1
1,433Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2K6TCA5A0A2K6TCA5_SAIBB
Spectrin repeat containing nuclear ...
SYNE1
473Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2K6TCB1A0A2K6TCB1_SAIBB
Spectrin repeat containing nuclear ...
SYNE1
611Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSSBOT00000033863; ENSSBOP00000017056; ENSSBOG00000023809

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSSBOT00000033863; ENSSBOP00000017056; ENSSBOG00000023809

Phylogenomic databases

GeneTreeiENSGT00940000154481

Family and domain databases

CDDicd00014, CH, 2 hits
Gene3Di1.10.418.10, 2 hits
InterProiView protein in InterPro
IPR001589, Actinin_actin-bd_CS
IPR001715, CH-domain
IPR036872, CH_dom_sf
IPR012315, KASH
IPR018159, Spectrin/alpha-actinin
IPR002017, Spectrin_repeat
PfamiView protein in Pfam
PF00307, CH, 2 hits
PF10541, KASH, 1 hit
PF00435, Spectrin, 12 hits
SMARTiView protein in SMART
SM00033, CH, 2 hits
SM01249, KASH, 1 hit
SM00150, SPEC, 42 hits
SUPFAMiSSF47576, SSF47576, 1 hit
PROSITEiView protein in PROSITE
PS00019, ACTININ_1, 1 hit
PS00020, ACTININ_2, 1 hit
PS50021, CH, 2 hits
PS51049, KASH, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2K6TBN9_SAIBB
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2K6TBN9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: January 19, 2022
This is version 16 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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