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Protein
Submitted name:

Adhesion G protein-coupled receptor G6

Gene

ADGRG6

Organism
Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Adhesion G protein-coupled receptor G6Imported
Gene namesi
Name:ADGRG6Imported
OrganismiSaimiri boliviensis boliviensis (Bolivian squirrel monkey)Imported
Taxonomic identifieri39432 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeSaimiriinaeSaimiri
Proteomesi
  • UP000233220 Componenti: Whole Genome Shotgun Assembly

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei838 – 861HelicalSequence analysisAdd BLAST24
Transmembranei873 – 894HelicalSequence analysisAdd BLAST22
Transmembranei900 – 922HelicalSequence analysisAdd BLAST23
Transmembranei942 – 963HelicalSequence analysisAdd BLAST22
Transmembranei991 – 1021HelicalSequence analysisAdd BLAST31
Transmembranei1042 – 1061HelicalSequence analysisAdd BLAST20
Transmembranei1067 – 1089HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 37Sequence analysisAdd BLAST37
ChainiPRO_501431881938 – 1222Sequence analysisAdd BLAST1185

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi94 ↔ 111PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 149CUBInterPro annotationAdd BLAST109
Domaini772 – 824GPSInterPro annotationAdd BLAST53
Domaini836 – 1090G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST255

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00930000150821
KOiK08463

Family and domain databases

CDDicd00041 CUB, 1 hit
Gene3Di2.60.120.290, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000859 CUB_dom
IPR017981 GPCR_2-like
IPR000832 GPCR_2_secretin-like
IPR017983 GPCR_2_secretin-like_CS
IPR000203 GPS
IPR001759 Pentraxin-related
IPR035914 Sperma_CUB_dom_sf
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF00431 CUB, 1 hit
PF01825 GPS, 1 hit
PF00354 Pentaxin, 1 hit
PRINTSiPR00249 GPCRSECRETIN
SMARTiView protein in SMART
SM00042 CUB, 1 hit
SM00303 GPS, 1 hit
SM00159 PTX, 1 hit
SUPFAMiSSF49854 SSF49854, 1 hit
SSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS01180 CUB, 1 hit
PS00650 G_PROTEIN_RECEP_F2_2, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
PS50221 GPS, 1 hit
PS51828 PTX_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A2K6SCN4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMFHSDRMWS CHWKWKPNPL LFLLALYIMC VPRSVSGCAN CRVVLSNPSG
60 70 80 90 100
TFTSPCYPND YPNSQACMWT LRAPTGYIIQ ITFNDFDIEE APNCIYDSLS
110 120 130 140 150
LDNGESQTKF CGATAKGLSF NSSVNEMHVS FSSDFSIQKK GFNASYIRVA
160 170 180 190 200
VSLRNQKVIL PQTSDAYQVS IAKSVSIPEL SAFTLCFEAT KVGHEDNDWT
210 220 230 240 250
AFSYSNASFT QLLSFGKAKS GYFLSISDSK CLLNNALPIK EKEDIFAESF
260 270 280 290 300
EQLCLVWNNS LGSVGVNFKR NYEIVQCDST ISKVIPGNGK LFLGSNQNEI
310 320 330 340 350
ASLKGDIYNF RLWNFTMNSK ILSNLSCNVK GNVVDWQNDF WNIPNLALKA
360 370 380 390 400
ESNLSCGSYL IPLPAAELAS CADLGTLCQD GILYRISVVI QNILRHPEVK
410 420 430 440 450
IQSKVAEWLN STFQNWNYTV YVINISFHLS SGEDKIKVKR STENDSRLVL
460 470 480 490 500
WALLVYNATN NTNLEGKIIQ QKLLKSNESL DEGLRLHRVN VRQLYLCPAV
510 520 530 540 550
EEPEGFKWPS IVPSEYTLPC PEKPGFNVTR ICFYNASNFS ETYWGPVDIS
560 570 580 590 600
NCLKEANEVA TQILNYTADG QNLTSANIID IVEQVKRIVN KEENIDITLG
610 620 630 640 650
STLMSIFSNI LSSSDSDLLE SSSEALKTID ELAFKIDLNN ISHVNITTQN
660 670 680 690 700
LALGVSSLLP GTNAISNFSI GLPSNNESYF QMDFESGQVD PLASVILPPN
710 720 730 740 750
LLENLSQEDA ALVRRAQFTF FNKTGLFQDV GPQRNPLVSY VMACSIGNIT
760 770 780 790 800
IQNLKDPVQI KIKHMSTQEV HHPICAFWDL NKNKSFGGWN TSGCVAHRDS
810 820 830 840 850
DASETVCLCN HFTHFGVLMD LSRSTSQLDA RNTKVLTFIT YIGCGISAIF
860 870 880 890 900
SAVTLLTYVA FEKLRRDYPS KILMNLSTAL LFLNLLFLLD GWITSFNVDG
910 920 930 940 950
LCIAIAALLH FFLLATFTWM GLEAIHMYIA LVKVFNTYIR RYILKFCIIG
960 970 980 990 1000
WGLPALVVSV ILVSRNKNEV YGKESYGKEK SDEFCWIQDP VIFYVTCAGY
1010 1020 1030 1040 1050
FGIMFFLNIA MFIVVMVQIC GRNGKRSNQT LRDEVLRNLR SVVSLTFLLG
1060 1070 1080 1090 1100
MTWGFAFFAW GPLNIPFLYL FAIFNSLQGL FIFIFHCAMK ENVQKQWRRH
1110 1120 1130 1140 1150
LCCGRFRLAD NSDWSKTATN IIKKSSDNLG KSLSSSSIGS NSTYLTSKSK
1160 1170 1180 1190 1200
SSSITYFKRN SHTDNTSMDK SLSKLAHADG EQTSIIPVHQ VIDKVKGYCN
1210 1220
AHSDNFYKNI IMSDTFSHST KF
Length:1,222
Mass (Da):137,124
Last modified:March 28, 2018 - v1
Checksum:i8116567BAA2ACEB5
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2K6SCM5A0A2K6SCM5_SAIBB
Adhesion G protein-coupled receptor...
ADGRG6
1,250Annotation score:
A0A2K6SCQ0A0A2K6SCQ0_SAIBB
Adhesion G protein-coupled receptor...
ADGRG6
1,011Annotation score:

Sequence databases

RefSeqiXP_003926913.1, XM_003926864.2

Genome annotation databases

EnsembliENSSBOT00000021720; ENSSBOP00000005143; ENSSBOG00000019284
GeneIDi101047458
KEGGisbq:101047458

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_003926913.1, XM_003926864.2

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSSBOT00000021720; ENSSBOP00000005143; ENSSBOG00000019284
GeneIDi101047458
KEGGisbq:101047458

Organism-specific databases

CTDi57211

Phylogenomic databases

GeneTreeiENSGT00930000150821
KOiK08463

Family and domain databases

CDDicd00041 CUB, 1 hit
Gene3Di2.60.120.290, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000859 CUB_dom
IPR017981 GPCR_2-like
IPR000832 GPCR_2_secretin-like
IPR017983 GPCR_2_secretin-like_CS
IPR000203 GPS
IPR001759 Pentraxin-related
IPR035914 Sperma_CUB_dom_sf
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF00431 CUB, 1 hit
PF01825 GPS, 1 hit
PF00354 Pentaxin, 1 hit
PRINTSiPR00249 GPCRSECRETIN
SMARTiView protein in SMART
SM00042 CUB, 1 hit
SM00303 GPS, 1 hit
SM00159 PTX, 1 hit
SUPFAMiSSF49854 SSF49854, 1 hit
SSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS01180 CUB, 1 hit
PS00650 G_PROTEIN_RECEP_F2_2, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
PS50221 GPS, 1 hit
PS51828 PTX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2K6SCN4_SAIBB
AccessioniPrimary (citable) accession number: A0A2K6SCN4
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: November 7, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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