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Protein
Submitted name:

Adhesion G protein-coupled receptor G6

Gene

ADGRG6

Organism
Saimiri boliviensis boliviensis (Bolivian squirrel monkey)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
Adhesion G protein-coupled receptor G6Imported
Gene namesi
Name:ADGRG6Imported
OrganismiSaimiri boliviensis boliviensis (Bolivian squirrel monkey)Imported
Taxonomic identifieri39432 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniPlatyrrhiniCebidaeSaimiriinaeSaimiri
Proteomesi
  • UP000233220 Componenti: Whole Genome Shotgun Assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei866 – 889HelicalSequence analysisAdd BLAST24
Transmembranei901 – 922HelicalSequence analysisAdd BLAST22
Transmembranei928 – 950HelicalSequence analysisAdd BLAST23
Transmembranei970 – 991HelicalSequence analysisAdd BLAST22
Transmembranei1019 – 1049HelicalSequence analysisAdd BLAST31
Transmembranei1070 – 1089HelicalSequence analysisAdd BLAST20
Transmembranei1095 – 1117HelicalSequence analysisAdd BLAST23

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 37Sequence analysisAdd BLAST37
ChainiPRO_501433889238 – 1250Sequence analysisAdd BLAST1213

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi94 ↔ 111PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 149CUBInterPro annotationAdd BLAST109
Domaini800 – 852GPSInterPro annotationAdd BLAST53
Domaini864 – 1118G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST255

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00930000150821

Family and domain databases

CDDicd00041 CUB, 1 hit
Gene3Di2.60.120.290, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000859 CUB_dom
IPR017981 GPCR_2-like
IPR000832 GPCR_2_secretin-like
IPR017983 GPCR_2_secretin-like_CS
IPR000203 GPS
IPR001759 Pentraxin-related
IPR035914 Sperma_CUB_dom_sf
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF00431 CUB, 1 hit
PF01825 GPS, 1 hit
PF00354 Pentaxin, 1 hit
PRINTSiPR00249 GPCRSECRETIN
SMARTiView protein in SMART
SM00042 CUB, 1 hit
SM00303 GPS, 1 hit
SM00159 PTX, 1 hit
SUPFAMiSSF49854 SSF49854, 1 hit
SSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS01180 CUB, 1 hit
PS00650 G_PROTEIN_RECEP_F2_2, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
PS50221 GPS, 1 hit
PS51828 PTX_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A2K6SCM5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMFHSDRMWS CHWKWKPNPL LFLLALYIMC VPRSVSGCAN CRVVLSNPSG
60 70 80 90 100
TFTSPCYPND YPNSQACMWT LRAPTGYIIQ ITFNDFDIEE APNCIYDSLS
110 120 130 140 150
LDNGESQTKF CGATAKGLSF NSSVNEMHVS FSSDFSIQKK GFNASYIRVA
160 170 180 190 200
VSLRNQKVIL PQTSDAYQVS IAKSVSIPEL SAFTLCFEAT KVGHEDNDWT
210 220 230 240 250
AFSYSNASFT QLLSFGKAKS GYFLSISDSK CLLNNALPIK EKEDIFAESF
260 270 280 290 300
EQLCLVWNNS LGSVGVNFKR NYEIVQCDST ISKVIPGNGK LFLGSNQNEI
310 320 330 340 350
ASLKGDIYNF RLWNFTMNSK ILSNLSCNVK GNVVDWQNDF WNIPNLALKA
360 370 380 390 400
ESNLSCGSYL IPLPAAELAS CADLGTLCQA TVNSPSTTPR TVTTNMPVTN
410 420 430 440 450
RIDKQMNDGI LYRISVVIQN ILRHPEVKIQ SKVAEWLNST FQNWNYTVYV
460 470 480 490 500
INISFHLSSG EDKIKVKRST ENDSRLVLWA LLVYNATNNT NLEGKIIQQK
510 520 530 540 550
LLKSNESLDE GLRLHRVNVR QLYLCPAVEE PEGFKWPSIV PSEYTLPCPE
560 570 580 590 600
KPGFNVTRIC FYNASNFSET YWGPVDISNC LKEANEVATQ ILNYTADGQN
610 620 630 640 650
LTSANIIDIV EQVKRIVNKE ENIDITLGST LMSIFSNILS SSDSDLLESS
660 670 680 690 700
SEALKTIDEL AFKIDLNNIS HVNITTQNLA LGVSSLLPGT NAISNFSIGL
710 720 730 740 750
PSNNESYFQM DFESGQVDPL ASVILPPNLL ENLSQEDAAL VRRAQFTFFN
760 770 780 790 800
KTGLFQDVGP QRNPLVSYVM ACSIGNITIQ NLKDPVQIKI KHMSTQEVHH
810 820 830 840 850
PICAFWDLNK NKSFGGWNTS GCVAHRDSDA SETVCLCNHF THFGVLMDLS
860 870 880 890 900
RSTSQLDARN TKVLTFITYI GCGISAIFSA VTLLTYVAFE KLRRDYPSKI
910 920 930 940 950
LMNLSTALLF LNLLFLLDGW ITSFNVDGLC IAIAALLHFF LLATFTWMGL
960 970 980 990 1000
EAIHMYIALV KVFNTYIRRY ILKFCIIGWG LPALVVSVIL VSRNKNEVYG
1010 1020 1030 1040 1050
KESYGKEKSD EFCWIQDPVI FYVTCAGYFG IMFFLNIAMF IVVMVQICGR
1060 1070 1080 1090 1100
NGKRSNQTLR DEVLRNLRSV VSLTFLLGMT WGFAFFAWGP LNIPFLYLFA
1110 1120 1130 1140 1150
IFNSLQGLFI FIFHCAMKEN VQKQWRRHLC CGRFRLADNS DWSKTATNII
1160 1170 1180 1190 1200
KKSSDNLGKS LSSSSIGSNS TYLTSKSKSS SITYFKRNSH TDNTSMDKSL
1210 1220 1230 1240 1250
SKLAHADGEQ TSIIPVHQVI DKVKGYCNAH SDNFYKNIIM SDTFSHSTKF
Length:1,250
Mass (Da):140,182
Last modified:March 28, 2018 - v1
Checksum:i905CC5094A11D78C
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2K6SCN4A0A2K6SCN4_SAIBB
Adhesion G protein-coupled receptor...
ADGRG6
1,222Annotation score:
A0A2K6SCQ0A0A2K6SCQ0_SAIBB
Adhesion G protein-coupled receptor...
ADGRG6
1,011Annotation score:

Sequence databases

RefSeqiXP_010335853.1, XM_010337551.1

Genome annotation databases

EnsembliENSSBOT00000021713; ENSSBOP00000005138; ENSSBOG00000019284
GeneIDi101047458

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_010335853.1, XM_010337551.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

GPCRDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSSBOT00000021713; ENSSBOP00000005138; ENSSBOG00000019284
GeneIDi101047458

Organism-specific databases

CTDi57211

Phylogenomic databases

GeneTreeiENSGT00930000150821

Family and domain databases

CDDicd00041 CUB, 1 hit
Gene3Di2.60.120.290, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000859 CUB_dom
IPR017981 GPCR_2-like
IPR000832 GPCR_2_secretin-like
IPR017983 GPCR_2_secretin-like_CS
IPR000203 GPS
IPR001759 Pentraxin-related
IPR035914 Sperma_CUB_dom_sf
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF00431 CUB, 1 hit
PF01825 GPS, 1 hit
PF00354 Pentaxin, 1 hit
PRINTSiPR00249 GPCRSECRETIN
SMARTiView protein in SMART
SM00042 CUB, 1 hit
SM00303 GPS, 1 hit
SM00159 PTX, 1 hit
SUPFAMiSSF49854 SSF49854, 1 hit
SSF49899 SSF49899, 1 hit
PROSITEiView protein in PROSITE
PS01180 CUB, 1 hit
PS00650 G_PROTEIN_RECEP_F2_2, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit
PS50221 GPS, 1 hit
PS51828 PTX_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2K6SCM5_SAIBB
AccessioniPrimary (citable) accession number: A0A2K6SCM5
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: November 7, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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