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Protein
Submitted name:

Uncharacterized protein

Gene

PTPN7

Organism
Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.SAAS annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei362SubstrateUniRule annotation1
Active sitei396Phosphocysteine intermediateUniRule annotation1
Binding sitei440SubstrateUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Protein phosphataseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:PTPN7Imported
OrganismiRhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana)Imported
Taxonomic identifieri61622 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeColobinaeRhinopithecus
Proteomesi
  • UP000233200 Componenti: Whole Genome Shotgun Assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini202 – 455Tyrosine-protein phosphataseInterPro annotationAdd BLAST254
Domaini373 – 446TYR_PHOSPHATASE_2InterPro annotationAdd BLAST74

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni396 – 402Substrate bindingUniRule annotation7

Phylogenomic databases

GeneTreeiENSGT00920000148980

Family and domain databases

Gene3Di3.90.190.10, 1 hit
InterProiView protein in InterPro
IPR029021 Prot-tyrosine_phosphatase-like
IPR000242 PTPase_domain
IPR016130 Tyr_Pase_AS
IPR003595 Tyr_Pase_cat
IPR008356 Tyr_Pase_KIM-con
IPR000387 TYR_PHOSPHATASE_dom
PfamiView protein in Pfam
PF00102 Y_phosphatase, 1 hit
PRINTSiPR01778 KIMPTPASE
PR00700 PRTYPHPHTASE
SMARTiView protein in SMART
SM00194 PTPc, 1 hit
SM00404 PTPc_motif, 1 hit
SUPFAMiSSF52799 SSF52799, 1 hit
PROSITEiView protein in PROSITE
PS00383 TYR_PHOSPHATASE_1, 1 hit
PS50056 TYR_PHOSPHATASE_2, 1 hit
PS50055 TYR_PHOSPHATASE_PTP, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A2K6PAY3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
IVGKAWPLTH SQGTGPWAPE GHRREAADPW WQRQQAQEGR MQLGCAWVAA
60 70 80 90 100
RRGGGRKLAS WSLLSPQRQT DRQTDSWQEA AWGPQLLQQT SWLNEPPLGL
110 120 130 140 150
APHPSMVQAC GGRSRAQPLT LSLGAAMTQP PPAKTPAKKH VRLQERRGSN
160 170 180 190 200
VALMLDVRSL GAVEPICSVN TPREVTLHFL RTAGHPLTRW ALQHQPPSPK
210 220 230 240 250
QLEEEFLKIP SNFVSPEDLD IPGHASKDRY KTILPNPQSR VCLGRAQSQE
260 270 280 290 300
DGDYINANYI RGYDGKEKVY IATQGPMPNT VSDFWEMVWQ EEVSLIVMLT
310 320 330 340 350
QLREGKEKCV HYWPTEEETY GPFQIRIQDM KECPEYTVRQ LTIQYREECR
360 370 380 390 400
SVKHILFSAW PDHQTPESAG PLLRLVAEVE ESPETAAHPG PIVVHCSAGI
410 420 430 440 450
GRTGCFIATR IGCQQLKARR EVDILGIVCQ LRLDRGGMIQ TAEQYQFLHH
460
TLALYAGQLP EEPSPPSP
Length:468
Mass (Da):52,538
Last modified:March 28, 2018 - v1
Checksum:iE1830FED3DB930C9
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2K6PAY0A0A2K6PAY0_RHIRO
Uncharacterized protein
PTPN7
116Annotation score:

Genome annotation databases

EnsembliENSRROT00000037823; ENSRROP00000013698; ENSRROG00000031082

Similar proteinsi

Cross-referencesi

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRROT00000037823; ENSRROP00000013698; ENSRROG00000031082

Phylogenomic databases

GeneTreeiENSGT00920000148980

Family and domain databases

Gene3Di3.90.190.10, 1 hit
InterProiView protein in InterPro
IPR029021 Prot-tyrosine_phosphatase-like
IPR000242 PTPase_domain
IPR016130 Tyr_Pase_AS
IPR003595 Tyr_Pase_cat
IPR008356 Tyr_Pase_KIM-con
IPR000387 TYR_PHOSPHATASE_dom
PfamiView protein in Pfam
PF00102 Y_phosphatase, 1 hit
PRINTSiPR01778 KIMPTPASE
PR00700 PRTYPHPHTASE
SMARTiView protein in SMART
SM00194 PTPc, 1 hit
SM00404 PTPc_motif, 1 hit
SUPFAMiSSF52799 SSF52799, 1 hit
PROSITEiView protein in PROSITE
PS00383 TYR_PHOSPHATASE_1, 1 hit
PS50056 TYR_PHOSPHATASE_2, 1 hit
PS50055 TYR_PHOSPHATASE_PTP, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2K6PAY3_RHIRO
AccessioniPrimary (citable) accession number: A0A2K6PAY3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: October 10, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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