Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Uncharacterized protein

Gene

PKD2

Organism
Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi764 – 775PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:PKD2Imported
OrganismiRhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana)Imported
Taxonomic identifieri61622 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeColobinaeRhinopithecus
Proteomesi
  • UP000233200 Componenti: Whole Genome Shotgun Assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei225 – 249HelicalSequence analysisAdd BLAST25
Transmembranei424 – 444HelicalSequence analysisAdd BLAST21
Transmembranei464 – 489HelicalSequence analysisAdd BLAST26
Transmembranei510 – 528HelicalSequence analysisAdd BLAST19
Transmembranei557 – 578HelicalSequence analysisAdd BLAST22
Transmembranei598 – 620HelicalSequence analysisAdd BLAST23
Transmembranei660 – 681HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini751 – 786EF-handInterPro annotationAdd BLAST36

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili393 – 413Sequence analysisAdd BLAST21
Coiled coili769 – 793Sequence analysisAdd BLAST25

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

GeneTreeiENSGT00700000104221
KOiK04986

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
IPR013122 PKD1_2_channel
IPR003915 PKD_2
IPR027359 Volt_channel_dom_sf
PfamiView protein in Pfam
PF08016 PKD_channel, 1 hit
PRINTSiPR01433 POLYCYSTIN2
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS50222 EF_HAND_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2K6P9H9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVNSSRVQPQ QPGDAKRPPA PRAPDPGRLM AGCAAVGASL AAPGGLREQR
60 70 80 90 100
GLEIEMQRIR QAAARDPPAG ASASPSPPLS SCSRQAWSRD NPGFEAEEEE
110 120 130 140 150
EEEVEGEEGG MVVEMDVEWR PGSRRSAASS AVSSAGARGR GLGGYHSTGH
160 170 180 190 200
PSGRRRRRED QGPPCPSPAG GGDPLHRHLP LDGQAPRVAW AERLVRGLRG
210 220 230 240 250
LWGTRFMEES STNREKYLKI VLRELVTYLL FLIVLCILTY GMMSSNVYYY
260 270 280 290 300
TRMMSQLFLD TPVSKTENTN FKTLSSMEDF WKFTEGSLLD GLYWKMQPSN
310 320 330 340 350
QTEADNRSFI FYENLLLGVP RIRQLRVRNG SCSIPQDLRD EIKECYDVYS
360 370 380 390 400
VSSEDRAPFG PRNGTAWIYT SEKDLNGSSH WGIIATYSGA GYYLDLSRRR
410 420 430 440 450
EETAAQVASL KKNVWLDRGT RATFIDFSVY NANINLFCVV RLLVEFPATG
460 470 480 490 500
GVIPSWQFQP LKLIRYVTTF DFFLAACEII FCFFILYYVV EEILEIRIHK
510 520 530 540 550
LHYFRSFWNC LDVVIVVLSV VAIGINIYRT SNVEVLLQFL EDQNTFPNFE
560 570 580 590 600
HLAYWQIQFN NIAAVTVFFV WIKLFKFINF NRTMSQLSTT MSRCAKDLFG
610 620 630 640 650
FAIMFFIIFL AYAQLAYLVF GTQVDDFSTF QECIFTQFRI ILGDINFAEI
660 670 680 690 700
EEANRVLGPI YFTTFVFFMF FILLNMFLAI INDTYSEVKS DLAQQKAEME
710 720 730 740 750
LSDLIRKGYH KALVKLKLKK NTVDDISESL RQGGGKLNFD ELRQDLKGKG
760 770 780 790 800
HTDAEIEAIF TKYDQDGDQE LTEHEHQQMR DDLEKEREDL DLDHSSLPRP
810 820 830 840 850
MSSRSFPRSL DDSEEDDDED SGHSSRRRGS ISSGVSYEEF QVLVRRVDRM
860 870 880 890 900
EHSIGSIVSK IDAVIVKLEI MERAKLKRRE VLGRLLDGVA EDERLGRDSE
910 920 930 940 950
IHREQMERLV REELERWESD DAASQISHGL GTPVGLNGQP RPRSSRPSSS
960
QSTEGMEGAG GNGSSNVHV
Length:969
Mass (Da):109,890
Last modified:March 28, 2018 - v1
Checksum:iDE29802E51085E4F
GO

Sequence databases

RefSeqiXP_010364456.1, XM_010366154.1

Genome annotation databases

EnsembliENSRROT00000037321; ENSRROP00000013198; ENSRROG00000030863
GeneIDi104664612
KEGGirro:104664612

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_010364456.1, XM_010366154.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRROT00000037321; ENSRROP00000013198; ENSRROG00000030863
GeneIDi104664612
KEGGirro:104664612

Organism-specific databases

CTDi5311

Phylogenomic databases

GeneTreeiENSGT00700000104221
KOiK04986

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR002048 EF_hand_dom
IPR013122 PKD1_2_channel
IPR003915 PKD_2
IPR027359 Volt_channel_dom_sf
PfamiView protein in Pfam
PF08016 PKD_channel, 1 hit
PRINTSiPR01433 POLYCYSTIN2
SUPFAMiSSF47473 SSF47473, 1 hit
PROSITEiView protein in PROSITE
PS50222 EF_HAND_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2K6P9H9_RHIRO
AccessioniPrimary (citable) accession number: A0A2K6P9H9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: November 7, 2018
This is version 8 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again