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Protein
Submitted name:

Uncharacterized protein

Gene

CLGN

Organism
Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperoneUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Uncharacterized proteinImported
Gene namesi
Name:CLGNImported
OrganismiRhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana)Imported
Taxonomic identifieri61622 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeColobinaeRhinopithecus
Proteomesi
  • UP000233200 Componenti: Whole Genome Shotgun Assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei471 – 492HelicalUniRule annotationAdd BLAST22

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19UniRule annotationAdd BLAST19
ChainiPRO_501421208720 – 610UniRule annotationAdd BLAST591

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the calreticulin family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalUniRule annotation, Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

GeneTreeiENSGT00430000030841
KOiK09551

Family and domain databases

Gene3Di2.10.250.10, 1 hit
InterProiView protein in InterPro
IPR001580 Calret/calnex
IPR018124 Calret/calnex_CS
IPR009033 Calreticulin/calnexin_P_dom_sf
IPR013320 ConA-like_dom_sf
PANTHERiPTHR11073 PTHR11073, 1 hit
PfamiView protein in Pfam
PF00262 Calreticulin, 1 hit
PRINTSiPR00626 CALRETICULIN
SUPFAMiSSF49899 SSF49899, 1 hit
SSF63887 SSF63887, 1 hit
PROSITEiView protein in PROSITE
PS00803 CALRETICULIN_1, 1 hit
PS00804 CALRETICULIN_2, 1 hit
PS00805 CALRETICULIN_REPEAT, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

A0A2K6NSB1-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRFQVFWLCL GLLFISINAE FMDDDVEMEN FEENSEEIDV NEGELSSEIK
60 70 80 90 100
YKTPQPIGEV YFAETFDSGR LAGWVLSKAK KDDMDEEISI YDGRWEIEEL
110 120 130 140 150
KENQVPGDRG LVLKSRAKHH AISAVLAKPF IFADKPLIVQ YEVNFQDGID
160 170 180 190 200
CGGAYIKLLA DTDDLILENF YDRTSYIIMF GPDKCGEDYK LHFIFRHKHP
210 220 230 240 250
KTGVFEEKHA KPPDVDLKKF FTDRKTHLYT LVMNPDDTFE VLVDQTVVNK
260 270 280 290 300
GSLLEDVVPP INPPKEIEDP SDKKPEEWDE RAKIPDPRAV KPEDWDESEP
310 320 330 340 350
AQIEDSSAVK PAGWLDDEPK FIHDPNAEKP DDWNEDMDGE WEAPQILNPA
360 370 380 390 400
CRIGCGEWKP PMIDNPKYKG VWRPPLVDNP TYQGIWSPRK IPNPDYFEDD
410 420 430 440 450
HPFLLTSFSA LGLELWSMTA DIYFDNFIIC SEKEVADHWA ADGWRWKIMI
460 470 480 490 500
ANANEPGVLK QLMAAAEGHP WLWLIYLITA GVPIALITSF CWPRKVKKKY
510 520 530 540 550
KDTEYKKTDI CIPQTKGVLE QEGKEEKAAL EKPMDLEEEK KQSDGEMLEK
560 570 580 590 600
EEESEPEEKS EEEIEILEGQ EERNKSNKSG SEDEMKEADE STGSGDGPMK
610
SVRKRRVRKD
Length:610
Mass (Da):70,183
Last modified:March 28, 2018 - v1
Checksum:iD3A8FC716D40AF08
GO

Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2K6NSB6A0A2K6NSB6_RHIRO
Uncharacterized protein
CLGN
537Annotation score:
A0A2K6NS92A0A2K6NS92_RHIRO
Uncharacterized protein
CLGN
460Annotation score:
A0A2K6NSC2A0A2K6NSC2_RHIRO
Uncharacterized protein
CLGN
431Annotation score:

Sequence databases

RefSeqiXP_010351764.1, XM_010353462.1

Genome annotation databases

EnsembliENSRROT00000030279; ENSRROP00000007153; ENSRROG00000027041
GeneIDi104654330
KEGGirro:104654330

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_010351764.1, XM_010353462.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRROT00000030279; ENSRROP00000007153; ENSRROG00000027041
GeneIDi104654330
KEGGirro:104654330

Organism-specific databases

CTDi1047

Phylogenomic databases

GeneTreeiENSGT00430000030841
KOiK09551

Family and domain databases

Gene3Di2.10.250.10, 1 hit
InterProiView protein in InterPro
IPR001580 Calret/calnex
IPR018124 Calret/calnex_CS
IPR009033 Calreticulin/calnexin_P_dom_sf
IPR013320 ConA-like_dom_sf
PANTHERiPTHR11073 PTHR11073, 1 hit
PfamiView protein in Pfam
PF00262 Calreticulin, 1 hit
PRINTSiPR00626 CALRETICULIN
SUPFAMiSSF49899 SSF49899, 1 hit
SSF63887 SSF63887, 1 hit
PROSITEiView protein in PROSITE
PS00803 CALRETICULIN_1, 1 hit
PS00804 CALRETICULIN_2, 1 hit
PS00805 CALRETICULIN_REPEAT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2K6NSB1_RHIRO
AccessioniPrimary (citable) accession number: A0A2K6NSB1
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: October 10, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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