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Protein

Protein transport protein sec16

Gene

SEC16B

Organism
Rhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus and for normal transitional endoplasmic reticulum (tER) organization.UniRule annotation

GO - Biological processi

Keywordsi

Biological processER-Golgi transportUniRule annotation, Protein transportUniRule annotation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Protein transport protein sec16UniRule annotation
Gene namesi
Name:SEC16BImported
OrganismiRhinopithecus bieti (Black snub-nosed monkey) (Pygathrix bieti)Imported
Taxonomic identifieri61621 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeColobinaeRhinopithecus
Proteomesi
  • UP000233180 Componenti: Unplaced

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulumUniRule annotation, Golgi apparatusUniRule annotation, MembraneUniRule annotation

Interactioni

Subunit structurei

SEC16A and SEC16B are each present in multiple copies in a heteromeric complex.UniRule annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini282 – 378Sec16InterPro annotationAdd BLAST97
Domaini447 – 680Sec16_CInterPro annotationAdd BLAST234

Sequence similaritiesi

Belongs to the SEC16 family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00530000063746

Family and domain databases

CDDicd09233 ACE1-Sec16-like, 1 hit
InterProiView protein in InterPro
IPR024298 ACE1_Sec16_Sec31
IPR024880 Sec16
IPR024340 Sec16_CCD
PfamiView protein in Pfam
PF12932 Sec16, 1 hit
PF12931 Sec16_C, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2K6KWS9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MELWAPQRLP QTRGKVTASS KDPDGGFWRD GHHRPVPHSR HSGERFHQWQ
60 70 80 90 100
DNRGSPQPQQ EPRADHQQSH YASRPGDWHQ PLSRTDYYES GYPSQLYSRP
110 120 130 140 150
GYENSYQGYH SPTMREEYAY GSYYYHGHPQ WLQEERVPRQ RSPYIWHEDY
160 170 180 190 200
REQKYLDEHH YENQHSPFGT NSETHFQSNS RNPYKDSPAS NSGQEWPGEL
210 220 230 240 250
FPGSLLAGAQ KNKPSLASES NLLQQRESGL SSSSYELSQY ITDAPERDDP
260 270 280 290 300
PASAAWSPVQ AEDVSSAGPK APMKFYVPHV PVSFGPGGQL VRVGPSSPTD
310 320 330 340 350
GQAALVELHS MEVILNDSEE QEEMRSFSGP LIREDIHKVD IMTFCQQKAA
360 370 380 390 400
QSCKSETLGS RDSALLWQLL VLLCRQNGSM VGSDIAELLM QDCKKLEKYQ
410 420 430 440 450
RQPPVANLIS LTDEDWPVLS SGTPNLLTGE IPPSVETPAQ IVEKFTRLLY
460 470 480 490 500
YGRKKEALEW AMKNHLWGHA LFLSSKMDPR TYSWVMSGFT STLAVNDPLQ
510 520 530 540 550
TLFQLMSGRI PQAATCCGEK QWGDWRPHLA VILSNQAGDP ELYQRAIVAM
560 570 580 590 600
GDTLAGKGLV EAAHFCYLMA HVPFGHYTVK TDHLVLLGSS HSQEFLKFAT
610 620 630 640 650
TEAIQRTEIF EYCQMLGRPK SFIPSFQVYK LLYASRLADY GLVSQALHYC
660 670 680 690 700
EAIGAAVLNQ GESSHPVLLA ELIKLAEKLK LSDPLVLERR SRDRDLEPDW
710 720 730 740 750
LVQLRRQLEQ KTAGDTGDPH PTRSAILGAR GTTTENTFYQ DFSGCQGYSE
760 770 780 790 800
APGYRSALWL TLEQTCLHQP SPQQPLPLQP GSYPAGGGAG QTGAPMPLYS
810 820 830 840 850
VPEIHLPGTG SSVAVTEAPG GTVWEETLQT HLGPGENTVS QETSQPPDGQ
860 870 880 890 900
EVISKAKTPL AARAPSISES STNSAKEDEE ESSDEADKNS PQNTARRGKL
910 920 930 940 950
RDGKEHTKSP GFGWFSWFRS KPTKNASPSG EEDSSDSPDS ERETPRASSP
960 970 980 990 1000
HQAGLGLSLT PSPESPPLPA LSAFSIGTGG GEGRGSTSSG GAAADAGVGG
1010 1020 1030 1040 1050
LSGPESVSFE LCSNPGVLLP PPALKGAVPL YNPSQVPQLP MATSLNRPNR
1060
LAQRRYPTQP C
Length:1,061
Mass (Da):116,807
Last modified:March 28, 2018 - v1
Checksum:iB57BA3E3588B45DE
GO

Sequence databases

RefSeqiXP_017747177.1, XM_017891688.1

Genome annotation databases

EnsembliENSRBIT00000039564; ENSRBIP00000015720; ENSRBIG00000031958
GeneIDi108541921

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_017747177.1, XM_017891688.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRBIT00000039564; ENSRBIP00000015720; ENSRBIG00000031958
GeneIDi108541921

Organism-specific databases

CTDi89866

Phylogenomic databases

GeneTreeiENSGT00530000063746

Family and domain databases

CDDicd09233 ACE1-Sec16-like, 1 hit
InterProiView protein in InterPro
IPR024298 ACE1_Sec16_Sec31
IPR024880 Sec16
IPR024340 Sec16_CCD
PfamiView protein in Pfam
PF12932 Sec16, 1 hit
PF12931 Sec16_C, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2K6KWS9_RHIBE
AccessioniPrimary (citable) accession number: A0A2K6KWS9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: September 12, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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