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Protein
Submitted name:

von Willebrand factor A domain containing 5B2

Gene

VWA5B2

Organism
Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
von Willebrand factor A domain containing 5B2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:VWA5B2Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPropithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri379532 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesStrepsirrhiniLemuriformesIndriidaePropithecus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000233160 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Whole Genome Shotgun Assembly

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 138VITInterPro annotationAdd BLAST138

Phylogenomic databases

Ensembl GeneTree

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GeneTreei
ENSGT00940000157096

Database of Orthologous Groups

More...
OrthoDBi
955432at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.50.410, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013694 VIT
IPR002035 VWF_A
IPR036465 vWFA_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13757 VIT_2, 1 hit
PF13768 VWA_3, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF53300 SSF53300, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51468 VIT, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

A0A2K6GF16-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPGLYCPSSW TPLPLTDSWV RACANGPCLS LRARLTYHNP QPQPVDGVFV
60 70 80 90 100
YPLAEAEVVS GFEAEAAGQR VSFQLQSRRR SQAACCRALG PGLGAATPRR
110 120 130 140 150
CAQGHLVLDL AQARSTLVLP TGLIAAAGTM TVTLHSSREL PSRPDGVLHV
160 170 180 190 200
ALPTVLTPLA LPGPPGPPRP PGLCDDSPTS CFGVGSPQEE GVPWEEPAAP
210 220 230 240 250
LDVFSGPARC PAPYTFSFEM LVTGPCLLAG LESPSHVLRA DAPPHASSAA
260 270 280 290 300
TICVTLAEGH RCDRALEILL HPSEPHQPHL MLEAGSLSSE EYEAQVRARR
310 320 330 340 350
DFQRLQRRDS DGDRQMWFLK RRFHKDIMLN PVLMLSFCPD LSSRPGHLGM
360 370 380 390 400
ATRELLFLLD GSSAAHKDAI VLAVKSLPPQ TLINLAMFGM SVQPLFPESR
410 420 430 440 450
PCSDDTVQLI CDSIETLQAV SGPPDVLAVL DWAMGQPQHR GHPRQLFLLT
460 470 480 490 500
AASPMAATTH QTLELMRWHR GAARCFSFGL GPACHQLLQG LSALSRGQAY
510 520 530 540 550
FLRPGERLQP MLVQALRKAL EPALSDISVD WFVPDAVEAL LTPREIPALY
560 570 580 590 600
PGDQLLGYCS LFRVDGFRPH PPGGQEPGWQ NLGGSVFPSP EEVPSAVSPS
610 620 630 640 650
TEPTGTSEPL GTGTVSAELS SPWAAGDSEQ STDALTDPVT DPGPNPSSDT
660 670 680 690 700
AIWRRIFQSS YIREQYVLTH CSASPEPGPG STGSSESPGS QGPGSPEGSA
710 720 730 740 750
PPDPPSQQGC RSLACGEHAG SRSCPLPASL PAPFKAGALS TEVLGRRRRV
760 770 780 790 800
ALAGRSLSSP PGRANPVSGR PQNPSLGAAP DGPGPEPGQQ LGQGLDDSGN
810 820 830 840 850
LLSPAPLDWD MLMEPPFLFM AMPPNGESAP PAVPLPPQAP RCHVVIRALC
860 870 880 890 900
GEQPMCWEVG VGLETLWGPG DGSQPLSPSV REAAWDQALH RLTAASVVRD
910 920 930 940 950
NEQLALRGGA ETTADHGHAR RCWLRALQTS KVSFAPSCFT CPVAVDATTR
960 970 980 990 1000
EVLPQALQVG SSEPAELPGT PPTSQNQLDA ASLPTRVHSK GLQGGSPAGA
1010 1020 1030 1040 1050
WHSDQNGNSK TALGDPVAHT RGPHRPPPQP PSRLSLGRRR RLCSPDPGQA
1060 1070 1080 1090 1100
CDSNSEGSDH DYLPLVRLQE APGSFRLDAP FCAAVRIPQE RLCRASPFAV
1110 1120 1130 1140 1150
HRASLSPTSS SSPWALLGPG VGQGDSATAS CSPSPSSGSE GPGQVDSGRG
1160 1170 1180 1190 1200
SDTEASEGAE GLGGTDLRGR SWATAVALAW LEHRCAAAFG EWELTAAKAD
1210 1220 1230 1240
CWLRAQHLPD GLDLAALKAA ARGLFLLLRH WDQNLQLHLL CYSPANV
Length:1,247
Mass (Da):132,020
Last modified:March 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iEF3E68F247FF06E7
GO

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_012496150.1, XM_012640696.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSPCOT00000035509; ENSPCOP00000024824; ENSPCOG00000024622

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
105807333

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_012496150.1, XM_012640696.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPCOT00000035509; ENSPCOP00000024824; ENSPCOG00000024622
GeneIDi105807333

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
90113

Phylogenomic databases

GeneTreeiENSGT00940000157096
OrthoDBi955432at2759

Family and domain databases

Gene3Di3.40.50.410, 1 hit
InterProiView protein in InterPro
IPR013694 VIT
IPR002035 VWF_A
IPR036465 vWFA_dom_sf
PfamiView protein in Pfam
PF13757 VIT_2, 1 hit
PF13768 VWA_3, 1 hit
SUPFAMiSSF53300 SSF53300, 1 hit
PROSITEiView protein in PROSITE
PS51468 VIT, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2K6GF16_PROCO
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2K6GF16
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: January 16, 2019
This is version 7 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
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