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Protein
Submitted name:

Nuclear receptor subfamily 3 group C member 2

Gene

NR3C2

Organism
Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi600 – 679Nuclear receptorPROSITE-ProRule annotationAdd BLAST80

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation, ReceptorSAAS annotation
Biological processTranscription, Transcription regulationPROSITE-ProRule annotationSAAS annotation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Nuclear receptor subfamily 3 group C member 2Imported
Gene namesi
Name:NR3C2Imported
OrganismiPropithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli)Imported
Taxonomic identifieri379532 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesStrepsirrhiniLemuriformesIndriidaePropithecus
Proteomesi
  • UP000233160 Componenti: Whole Genome Shotgun Assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini600 – 679Nuclear receptorInterPro annotationAdd BLAST80
Domaini729 – 967NR LBDInterPro annotationAdd BLAST239

Sequence similaritiesi

Belongs to the nuclear hormone receptor family.SAAS annotation

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

GeneTreeiENSGT00760000118887

Family and domain databases

Gene3Di3.30.50.10, 1 hit
InterProiView protein in InterPro
IPR035500 NHR_like_dom_sf
IPR000536 Nucl_hrmn_rcpt_lig-bd
IPR001628 Znf_hrmn_rcpt
IPR013088 Znf_NHR/GATA
PfamiView protein in Pfam
PF00104 Hormone_recep, 1 hit
PF00105 zf-C4, 1 hit
PRINTSiPR00047 STROIDFINGER
SMARTiView protein in SMART
SM00430 HOLI, 1 hit
SM00399 ZnF_C4, 1 hit
SUPFAMiSSF48508 SSF48508, 2 hits
PROSITEiView protein in PROSITE
PS51843 NR_LBD, 1 hit
PS00031 NUCLEAR_REC_DBD_1, 1 hit
PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2K6G5X7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
METKGYHSLP EGLDMERRWG QASQTMERSS LDPTEKTDEN NYMEIVNVSC
60 70 80 90 100
VSGAIPNNST QGSSKEKHEL LPCLQQDSSR SGILTSDVKT ELESKELSAT
110 120 130 140 150
VAESMGLYMD SVRDADYTYD QQNQQGSMSP AKVYQNVEQL MKFYKENGHR
160 170 180 190 200
PSTLSSVSRP LRSFMSDSGS SVNGGMMRAM VKSPIMCHEK SPSVCSPLNM
210 220 230 240 250
SSSVCSPAGI NSVSSTTASF GSFPVHSPIT QGTPLTCSPN VENRGSRSHS
260 270 280 290 300
PAHASNVGSP LSSPLSSMKS PISSPPSHCS VKSPVSSPNN VTLRSSVSSP
310 320 330 340 350
ANINNSRCSV SSPSNTNNRS TLSSPTASTV GSICSPINNA FSYPASSTSA
360 370 380 390 400
GSSATRDVVP SPDTHEKGAQ DVSFPKTEEV ESAISNGVTG QLNIIQYIKP
410 420 430 440 450
EPDGAFSSSC LGGNSKINSD SPFSVPIKQE STKHSCSGAS FKGNPTVNLF
460 470 480 490 500
PFMDGSYFSF MDDKDYYSLS GILGPPVPGF DGNCEGSGFP VGIKQEPDDG
510 520 530 540 550
SYYPEASIPS SAIVGVNSGG QSFHYRIGAQ GTISLSRSAR DQSFQHLSSF
560 570 580 590 600
PPVNTLVESW KSHGDLSSRR SDGYPVLEYI PENVSSSTLR SVSTGSSRPS
610 620 630 640 650
KICLVCGDEA SGCHYGVVTC GSCKVFFKRA VEGKCSWQHN YLCAGRNDCI
660 670 680 690 700
IDKIRRKNCP ACRLQKCLQA GMNLGARKSK KLGKLKGIHE EQPQQQPPPP
710 720 730 740 750
PPPPQSPEEG TTYIAPAKEP SVNTALVPQL STISRALTPS PAMLLESIEP
760 770 780 790 800
EIVYAGYDSS KPDTAENLLS TLNRLAGKQM IQVVKWAKVL PGFKNLPLED
810 820 830 840 850
QITLIQYSWM CLSSFALSWR SYKHTNSQFL YFAPDLVFNE EKMHQSAMYE
860 870 880 890 900
LCQGMHQISL QFVRLQLTFE EYSIMKVLLL LSTIPKDGLK SQAAFEEMRT
910 920 930 940 950
NYIKELRKMV TKCPNNSGQS WQRFYQLTKL LDSMHDLVSD LLEFCFYTFR
960 970 980
ESHALKVEFP AMLVEIISDQ LPKVESGNAK PLYFHRK
Length:987
Mass (Da):107,583
Last modified:March 28, 2018 - v1
Checksum:i8720355C01EE9739
GO

Genome annotation databases

EnsembliENSPCOT00000032311; ENSPCOP00000021644; ENSPCOG00000022854

Similar proteinsi

Entry informationi

Entry nameiA0A2K6G5X7_PROCO
AccessioniPrimary (citable) accession number: A0A2K6G5X7
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: June 20, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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