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Protein

Alpha-synuclein

Gene

SNCA

Organism
Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-synucleinUniRule annotation
Gene namesi
Name:SNCAImported
OrganismiPropithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli)Imported
Taxonomic identifieri379532 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesStrepsirrhiniLemuriformesIndriidaePropithecus
Proteomesi
  • UP000233160 Componenti: Whole Genome Shotgun Assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the synuclein family.UniRule annotation

Phylogenomic databases

GeneTreeiENSGT00390000016161

Family and domain databases

InterProiView protein in InterPro
IPR001058 Synuclein
IPR002460 Synuclein_alpha
PANTHERiPTHR13820 PTHR13820, 1 hit
PTHR13820:SF5 PTHR13820:SF5, 1 hit
PfamiView protein in Pfam
PF01387 Synuclein, 1 hit
PRINTSiPR01212 ASYNUCLEIN
PR01211 SYNUCLEIN

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

A0A2K6FYB9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDIFKKGLSK AKEGVVAAAE KTKQGVAEAA GKTKEGVLYV GSKTKEGVVH
60 70 80 90 100
GVTTVAEKTK EQVTNVGGAV VTGVTAVAQK TVEGAGSIAA ATGFGKKDQF
110 120 130 140
GKSEEGAPQE GILEDTPMDP DSEAYEMPSE EGYQDYEPEA
Length:140
Mass (Da):14,441
Last modified:March 28, 2018 - v1
Checksum:i4E96CFF4AFD53279
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2K6FYA6A0A2K6FYA6_PROCO
Alpha-synuclein
SNCA
126Annotation score:
A0A2K6FYA8A0A2K6FYA8_PROCO
Alpha-synuclein
SNCA
112Annotation score:

Sequence databases

RefSeqiXP_012502617.1, XM_012647163.1
XP_012502618.1, XM_012647164.1

Genome annotation databases

EnsembliENSPCOT00000029610; ENSPCOP00000018965; ENSPCOG00000021411
GeneIDi105812661

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_012502617.1, XM_012647163.1
XP_012502618.1, XM_012647164.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPCOT00000029610; ENSPCOP00000018965; ENSPCOG00000021411
GeneIDi105812661

Organism-specific databases

CTDi6622

Phylogenomic databases

GeneTreeiENSGT00390000016161

Family and domain databases

InterProiView protein in InterPro
IPR001058 Synuclein
IPR002460 Synuclein_alpha
PANTHERiPTHR13820 PTHR13820, 1 hit
PTHR13820:SF5 PTHR13820:SF5, 1 hit
PfamiView protein in Pfam
PF01387 Synuclein, 1 hit
PRINTSiPR01212 ASYNUCLEIN
PR01211 SYNUCLEIN
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2K6FYB9_PROCO
AccessioniPrimary (citable) accession number: A0A2K6FYB9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: October 10, 2018
This is version 6 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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