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Protein

Non-specific serine/threonine protein kinase

Gene

PAK4

Organism
Propithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Non-specific serine/threonine protein kinaseSAAS annotation (EC:2.7.11.1SAAS annotation)
Gene namesi
Name:PAK4Imported
OrganismiPropithecus coquereli (Coquerel's sifaka) (Propithecus verreauxi coquereli)Imported
Taxonomic identifieri379532 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesStrepsirrhiniLemuriformesIndriidaePropithecus
Proteomesi
  • UP000233160 Componenti: Whole Genome Shotgun Assembly

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini11 – 24CRIBInterPro annotationAdd BLAST14
Domaini318 – 569Protein kinaseInterPro annotationAdd BLAST252

Phylogenomic databases

GeneTreeiENSGT00930000150829

Family and domain databases

CDDicd01093 CRIB_PAK_like, 1 hit
Gene3Di3.90.810.10, 1 hit
InterProiView protein in InterPro
IPR000095 CRIB_dom
IPR036936 CRIB_dom_sf
IPR011009 Kinase-like_dom_sf
IPR033923 PAK_BD
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
PfamiView protein in Pfam
PF00786 PBD, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00285 PBD, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50108 CRIB, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

A0A2K6EWA9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MFGKKKKRVE ISAPSNFEHR VHTGFDQNEQ KFTGLPRQWQ SLIEESARRP
60 70 80 90 100
KPLVDPACIT SIQPGAPKTI VRGSKGAKDG ALTLLLDEFE NMSVTRSNSL
110 120 130 140 150
RRDSPPPPAR ARQENGMPEE QAATARGGPG KAGGRGRTAG HSEAGGSSGD
160 170 180 190 200
RRRVGPEKRP KSSREGSGGP QESSRDKRPL SGPDVGTPQP ASLASGAKLA
210 220 230 240 250
AGRPFNTYPR ADTDHPSRGA QGEPREMAPN GPSAGGLPVP QSSSRPATRT
260 270 280 290 300
RGPPGPGVLG PHASEPQLAP PARAPAAPAA PGPPGPRSPQ REPQRVSHEQ
310 320 330 340 350
FRAALQLVVD PGDPRSYLDN FIKIGEGSTG IVCIATVRSS GKLVAVKKMD
360 370 380 390 400
LRKQQRRELL FNEVVIMRDY QHENVVEMYN SYLVGDELWV VMEFLEGGAL
410 420 430 440 450
TDIVTHTRMN EEQIAAVCLA VLQALSVLHA QGVIHRDIKS DSILLTHDGR
460 470 480 490 500
VKLSDFGFCA QVSKEVPRRK SLVGTPYWMA PELISRLPYG PEVDIWSLGV
510 520 530 540 550
MVIEMVDGEP PYFNEPPLKA MKMIRDNLPP RLKNLHKVSP SLKGFLDRLL
560 570 580
VRDPAQRATA AELLKHPFLA KAGPPSSIVP LMRQNRTR
Length:588
Mass (Da):63,847
Last modified:March 28, 2018 - v1
Checksum:i10D77AA6A746AFD3
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2K6EWB0A0A2K6EWB0_PROCO
Non-specific serine/threonine prote...
PAK4
435Annotation score:

Sequence databases

RefSeqiXP_012512585.1, XM_012657131.1

Genome annotation databases

EnsembliENSPCOT00000016505; ENSPCOP00000006025; ENSPCOG00000014081
GeneIDi105820606

Similar proteinsi

Cross-referencesi

Sequence databases

RefSeqiXP_012512585.1, XM_012657131.1

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSPCOT00000016505; ENSPCOP00000006025; ENSPCOG00000014081
GeneIDi105820606

Organism-specific databases

CTDi10298

Phylogenomic databases

GeneTreeiENSGT00930000150829

Family and domain databases

CDDicd01093 CRIB_PAK_like, 1 hit
Gene3Di3.90.810.10, 1 hit
InterProiView protein in InterPro
IPR000095 CRIB_dom
IPR036936 CRIB_dom_sf
IPR011009 Kinase-like_dom_sf
IPR033923 PAK_BD
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
PfamiView protein in Pfam
PF00786 PBD, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00285 PBD, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50108 CRIB, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiA0A2K6EWA9_PROCO
AccessioniPrimary (citable) accession number: A0A2K6EWA9
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: November 7, 2018
This is version 7 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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