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Protein
Submitted name:

Transcription factor 7 like 1

Gene

TCF7L1

Organism
Macaca nemestrina (Pig-tailed macaque)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi347 – 415HMG boxPROSITE-ProRule annotationAdd BLAST69

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Transcription factor 7 like 1Imported
Gene namesi
Name:TCF7L1Imported
OrganismiMacaca nemestrina (Pig-tailed macaque)Imported
Taxonomic identifieri9545 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000233120 Componenti: Whole Genome Shotgun Assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini347 – 415HMG boxInterPro annotationAdd BLAST69

Phylogenomic databases

GeneTreeiENSGT00390000009964

Family and domain databases

Gene3Di1.10.30.10, 1 hit
4.10.900.10, 1 hit
InterProiView protein in InterPro
IPR027397 Catenin_binding_dom_sf
IPR013558 CTNNB1-bd_N
IPR009071 HMG_box_dom
IPR036910 HMG_box_dom_sf
IPR024940 TCF/LEF
IPR028773 TCF7L
PANTHERiPTHR10373 PTHR10373, 1 hit
PTHR10373:SF25 PTHR10373:SF25, 1 hit
PfamiView protein in Pfam
PF08347 CTNNB1_binding, 1 hit
PF00505 HMG_box, 1 hit
SMARTiView protein in SMART
SM00398 HMG, 1 hit
SUPFAMiSSF47095 SSF47095, 1 hit
PROSITEiView protein in PROSITE
PS50118 HMG_BOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

A0A2K6E949-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPQLGGGGGG GGGGGSGGGS GSSAGAAGGG DDLGANDELI PFQDEGGEEQ
60 70 80 90 100
EPSSDSASAQ RDLDEVKSSL VNESENQSSS SDSEAERRPQ PARDTFQKPR
110 120 130 140 150
DYFAEVRRPQ DSAFFKGPPY PGYPFLMIPD LSSPYLSNGP LSPGGARTYL
160 170 180 190 200
QMKWPLLDVP SSATVKDTRS PSPAHLSNKV PVVQHPHHMH PLTPLITYSN
210 220 230 240 250
DHFSPGSPPT HLSPEIDPKT GIPRPPHPSE LSPYYPLSPG AVGQIPHPLG
260 270 280 290 300
WLVPQQGQPV YSLPPGGFRH PYPALAMNAS MSSLVSSRFS PHMVAPAHPG
310 320 330 340 350
LPTSGIPHPA IVSPIVKQEP APPSLSPAVS AKSPVTVKKE EEKKPHVKKP
360 370 380 390 400
LNAFMLYMKE MRAKVVAECT LKESAAINQI LGRKWHNLSR EEQAKYYELA
410 420 430 440 450
RKERQLHSQL YPTWSARDNY GKKKKRKREK QLSQTQPQQQ VQEAEGALAS
460 470 480 490 500
KSKKPCVQYL PPEKPCDSPA SSHGSMLDSP ATPSAALASP AAPAATHSEQ
510 520 530 540 550
AQPLSLTTKP ETRAQLALHS AAFLSAKAAA SSSGQMGSQP PLLSRPLPLG
560 570 580
SMPTALLASP PSFPATLHAH QALPVLQAQP LSLVTKSAH
Length:589
Mass (Da):62,640
Last modified:March 28, 2018 - v1
Checksum:i28C5E4ECF5A86437
GO

Sequence databases

RefSeqiXP_011712084.1, XM_011713782.1

Genome annotation databases

EnsembliENSMNET00000069206; ENSMNEP00000044695; ENSMNEG00000044913
GeneIDi105465371

Similar proteinsi

Entry informationi

Entry nameiA0A2K6E949_MACNE
AccessioniPrimary (citable) accession number: A0A2K6E949
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: July 18, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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