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Protein
Submitted name:

Fibulin 2

Gene

FBLN2

Organism
Macaca nemestrina (Pig-tailed macaque)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Fibulin 2Imported
Gene namesi
Name:FBLN2Imported
OrganismiMacaca nemestrina (Pig-tailed macaque)Imported
Taxonomic identifieri9545 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
Proteomesi
  • UP000233120 Componenti: Whole Genome Shotgun Assembly

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 27Sequence analysisAdd BLAST27
ChainiPRO_501445756128 – 1225Sequence analysisAdd BLAST1198

Keywords - PTMi

Disulfide bondSAAS annotation

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini439 – 474Anaphylatoxin-likeInterPro annotationAdd BLAST36
Domaini482 – 513Anaphylatoxin-likeInterPro annotationAdd BLAST32
Domaini515 – 547Anaphylatoxin-likeInterPro annotationAdd BLAST33
Domaini598 – 639EGF-likeInterPro annotationAdd BLAST42
Domaini899 – 937EGF-likeInterPro annotationAdd BLAST39
Domaini942 – 983EGF-likeInterPro annotationAdd BLAST42
Domaini984 – 1022EGF-likeInterPro annotationAdd BLAST39

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili270 – 290Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, EGF-like domainPROSITE-ProRule annotationSAAS annotation, RepeatSAAS annotation, SignalSequence analysis

Phylogenomic databases

GeneTreeiENSGT00760000118806

Family and domain databases

InterProiView protein in InterPro
IPR000020 Anaphylatoxin/fibulin
IPR026823 cEGF
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR037286 Fibulin-2
IPR009030 Growth_fac_rcpt_cys_sf
PANTHERiPTHR44887 PTHR44887, 1 hit
PfamiView protein in Pfam
PF01821 ANATO, 1 hit
PF12662 cEGF, 2 hits
PF07645 EGF_CA, 6 hits
SMARTiView protein in SMART
SM00104 ANATO, 3 hits
SM00181 EGF, 12 hits
SM00179 EGF_CA, 10 hits
SUPFAMiSSF57184 SSF57184, 5 hits
PROSITEiView protein in PROSITE
PS01178 ANAPHYLATOXIN_2, 3 hits
PS00010 ASX_HYDROXYL, 4 hits
PS01186 EGF_2, 3 hits
PS50026 EGF_3, 4 hits
PS01187 EGF_CA, 3 hits

Sequencei

Sequence statusi: Complete.

A0A2K6CJU3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVLLWEPAGA WLALGLALAL GPSVAAAAPR QDCTGVECPP LENCIEEALE
60 70 80 90 100
PGACCATCVQ QGCACEGYQY YDCLQGGFVR GRVPAGQSYF VDFGSTECTC
110 120 130 140 150
PPGGGKISCQ FMLCPELPPN CIEAVVVADS CPQCGQVGCI HAGRKYAAGH
160 170 180 190 200
TVHLPPCRAC HCPDAGGELI CYQLPGCHGN FSDAEEGDPE RHYEDPYSYD
210 220 230 240 250
QEVAEVEAAA ALGGEVQAGA VQAGAGGPPA ALGGGSQPLS TIQAPPWPAA
260 270 280 290 300
LPRPTAAAAL GPPAPVQAKA RRVTEDSEEE EEEEEEREEM AVTEQLAAGG
310 320 330 340 350
HRGLDGLPTT APAGPSLPIQ EERAEAGARP EENLIPDAQA TSRSSGLEGM
360 370 380 390 400
TPAPGPGKAA LIPTQAVPGS PRDPVKPSPH TILSTPLPDA AWIPPTREVP
410 420 430 440 450
RKPQVLPHSH VEEDIDPNSV HSVPRSSPEG STKDLIETCC AAGQQWAIDN
460 470 480 490 500
DECLEIPESG TEGNICRTAQ RHCCVSYLKE KSCMAGVLGA KEGETCGAED
510 520 530 540 550
NDTCGISLYK QCCDCCGLGL RVRAEGQLCE SNPNLGYPCN HVMLSCCEGE
560 570 580 590 600
EPLIVPEVRR PPEPAAAPRR VSEAEMAGRE ALSLGTEAEL PNSLPGDDQD
610 620 630 640 650
ECLLLPGELC QHLCINTVGS YHCACFPGFS LQDDGRTCRP EGHPPQPEAP
660 670 680 690 700
QEPALKSEFS QVASNTIPLP LPQPNTCKDN GPCKQVCSTV GGSAICSCFP
710 720 730 740 750
GYAIMADGVS CEDRDECLMG AHDCSRRQFC VNTLGSFYCV NHTVLCADGY
760 770 780 790 800
ILNAHRKCVD INECVTDLHT CSRGEHCVNT LGSFHCYTAL TCEPGYALKD
810 820 830 840 850
GECEDVDECA MGTHTCQAGF LCQNTKGSFY CQARQRCMDG FLQDPEGNCV
860 870 880 890 900
DINECTSLSE PCRPGFSCIN TVGSYTCQRN PLICGRGYHA SDDGAKCVDV
910 920 930 940 950
NECETGVHRC GEGQVCHNLP GSYRCDCKAG FQRDAFGRGC IDVNECWASP
960 970 980 990 1000
GRLCQHTCEN TLGSYRCSCA SGFLLAADGK HCEDVNECEA QRCSQECANI
1010 1020 1030 1040 1050
YGSYQCYCRQ GYQLAEDGHT CTDIDECAQG AGILCTFRCL NVPGSYQCAC
1060 1070 1080 1090 1100
PEQGYTMTAN GRSCKDLDEC ALGTHNCSEA ETCHNIQGSF RCLRFECPPN
1110 1120 1130 1140 1150
YVRVSKTKCE RTTCHDFLEC QNSPARITHY QLNFQTGLLV PAHIFRIGPA
1160 1170 1180 1190 1200
PAFTGDTIAL TIIKGNEEGY FGTRRLNAYT GVVYLQRAVL EPRDFALDVE
1210 1220
MKLWRQGSVT TFLAKMHIFF TTFAL
Length:1,225
Mass (Da):131,174
Last modified:March 28, 2018 - v1
Checksum:i805DDFA77D0935AC
GO

Sequence databases

RefSeqiXP_011732743.1, XM_011734441.1
XP_011732744.1, XM_011734442.1

Genome annotation databases

EnsembliENSMNET00000048200; ENSMNEP00000023934; ENSMNEG00000035537
GeneIDi105477743

Similar proteinsi

Entry informationi

Entry nameiA0A2K6CJU3_MACNE
AccessioniPrimary (citable) accession number: A0A2K6CJU3
Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: July 18, 2018
This is version 4 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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