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Entry version 14 (11 Dec 2019)
Sequence version 1 (28 Mar 2018)
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Protein
Submitted name:

PATJ crumbs cell polarity complex component

Gene

PATJ

Organism
Macaca nemestrina (Pig-tailed macaque)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
PATJ crumbs cell polarity complex componentImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PATJImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMacaca nemestrina (Pig-tailed macaque)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9545 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniCercopithecidaeCercopithecinaeMacaca
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000233120 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Whole Genome Shotgun Assembly

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini5 – 65L27InterPro annotationAdd BLAST61
Domaini134 – 221PDZInterPro annotationAdd BLAST88
Domaini248 – 328PDZInterPro annotationAdd BLAST81
Domaini365 – 453PDZInterPro annotationAdd BLAST89
Domaini553 – 639PDZInterPro annotationAdd BLAST87
Domaini686 – 758PDZInterPro annotationAdd BLAST73
Domaini1069 – 1161PDZInterPro annotationAdd BLAST93
Domaini1240 – 1323PDZInterPro annotationAdd BLAST84
Domaini1438 – 1521PDZInterPro annotationAdd BLAST84
Domaini1534 – 1616PDZInterPro annotationAdd BLAST83
Domaini1677 – 1763PDZInterPro annotationAdd BLAST87

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1167 – 1225DisorderedSequence analysisAdd BLAST59
Regioni1337 – 1361DisorderedSequence analysisAdd BLAST25
Regioni1621 – 1643DisorderedSequence analysisAdd BLAST23
Regioni1783 – 1802DisorderedSequence analysisAdd BLAST20

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili495 – 515Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1167 – 1182PolarSequence analysisAdd BLAST16
Compositional biasi1337 – 1355PolarSequence analysisAdd BLAST19
Compositional biasi1784 – 1802PolyampholyteSequence analysisAdd BLAST19

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155136

Identification of Orthologs from Complete Genome Data

More...
OMAi
ELLEXNE

Database of Orthologous Groups

More...
OrthoDBi
1419918at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR015132 L27_2
IPR004172 L27_dom
IPR036892 L27_dom_sf
IPR001478 PDZ
IPR041489 PDZ_6
IPR036034 PDZ_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF09045 L27_2, 1 hit
PF00595 PDZ, 9 hits
PF17820 PDZ_6, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00569 L27, 1 hit
SM00228 PDZ, 10 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF101288 SSF101288, 1 hit
SSF50156 SSF50156, 10 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51022 L27, 1 hit
PS50106 PDZ, 10 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

A0A2K6B0E9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPENPATDKL QVLQVLDRLK MKLQEKGDTS QNEKLSVFYE TLKSPLFNQI
60 70 80 90 100
LTLQQSIKQL KGQLNHIPSD CSAHFDFSRK GLLVFTDGSI ANGNVHRPSN
110 120 130 140 150
NSTVSGLFPW TPKLGNEDFN SVIQQMAQGR QIEYIDIERP SSGGLGFSVV
160 170 180 190 200
ALRSQNMGNV DIFVKDVQPG SVADRDQRLK ENDQILAVNH TPLDQNVSHQ
210 220 230 240 250
QAIALLQQTT GSLQLIVARE PIHTKSSTSS SLTDTTLPET VCWGHVEEVE
260 270 280 290 300
LINDGSGLGF GIVGGKTSGV VVRTIVPGGL ADRDGRLQTG DHILKIGGTN
310 320 330 340 350
VQGMTSEQVA QVLRNCGNSV RMLVARDPAG DISVTPPAPA ALPVALPTVA
360 370 380 390 400
SKGPGSDSSL FETYNVELVK KDGQSLGIRI VGYVGTSHTG EASGIYVKSI
410 420 430 440 450
IPGSAAYHNG HIQVNDKIVA VNGVNIQGFA NQDVVEVLRN AGQVVHLTLV
460 470 480 490 500
RRKTSSSTSP LEPLSARGTV VEPPKPPALF LTGAVETETN VDGEQEEIKD
510 520 530 540 550
RMDNLKNDNI QALEKLEKAP DSPENELKSR WENLLGPDYE VMVATLDTQI
560 570 580 590 600
ADDAELQKYS KLLPIHTLRL GVEVDSFDGH HYISSIVSGG PVDTLGLLQP
610 620 630 640 650
EDELLEVNGT QLYGKSRREA VSFLKEVPPP FTLVCCRRLF DDEASVDEPR
660 670 680 690 700
CTETSLPEME IDRDMDVNAE EDDDGELALW SPEVKIVELV KDCKGLGFSI
710 720 730 740 750
LDYQDPLDST RSVIVIRSLV ADGVAERSGG LLPGDRLVSV NEYCLDNTSL
760 770 780 790 800
AEAVEILKAL PPGIVRLGIC KPLVEDNKEE ESCYILHSSS NEDKTELSGT
810 820 830 840 850
IHDINSSLIL EAPKGFRDEP YFKEELVDEP FLDLGKSFHS QQKEIEQSKE
860 870 880 890 900
TWEMHEFLTP RLQEMDEERE MLVDEEYELY QDPSQSMELY PLSHIQEATP
910 920 930 940 950
VPSLKELHFG TQWLHDNEPS ESQEARSGRN IYSQEAQPYG YCPENVMKEN
960 970 980 990 1000
FVMESLPSVP STEGNSQQCR FDDLENLNSL AKSSLDLGMI PDDAQGPSLL
1010 1020 1030 1040 1050
IDLPVVAQSR EQEDLPLYQH QVTRVISKTS AYTGMLSSRY ATDTCELPER
1060 1070 1080 1090 1100
EEGEGEETPN FSHWGPPRIV EIFREPNVSL GISIVGGQTV IKRLKNGEEL
1110 1120 1130 1140 1150
KGIFIKQVLE DSPAGKTNAL KTGDKILEVS GVDLQNASHS EAVEAIKNAG
1160 1170 1180 1190 1200
NPVVFVVQSL SSTPRVIPNV HNKANKITGN QNQDTQEKKE KRQGTAPPPM
1210 1220 1230 1240 1250
KLPPPYKARS DDSDENEEED AFTHQKIRQR YADLPGELHI IELEKDKNGL
1260 1270 1280 1290 1300
GLSLAGNKDR SRMSIFVVGI NPEGPAATDG RMRIGDELLE INNQILYGRS
1310 1320 1330 1340 1350
HQNASAIIKT APSKVKLVFI RNEDAVNQMA VPPFLVPSSS PSSIEDQSGT
1360 1370 1380 1390 1400
EPVSSEEDGS LEVGIKQLPE SESFKLAVSQ MKQQKYPTKV SFSSQEIPLA
1410 1420 1430 1440 1450
PDSSYHSTDA DFIGYGGFQA PLSVDPATCP IVPGQEMIIE ISKGRSGLGL
1460 1470 1480 1490 1500
SIVGGKDTPL NAIVIHEVYE EGAAARDGRL WAGDQILEVN GVDLRNSSHE
1510 1520 1530 1540 1550
EAITALRQTP QKVRLVVYRD EAHYRDEENL EMFPVDLQKK AGRGLGLSIV
1560 1570 1580 1590 1600
GKRNGSGVFI SDIVKGGAAD LDGRLIQGDQ ILSVNGEDMR NASQETVATI
1610 1620 1630 1640 1650
LKCAQGLVQL EIGRLRAGSW TSARQTPQNS QGSQQSAHSS CHPSFAPVIT
1660 1670 1680 1690 1700
GLQNLVGTKR VSDPSQKNSG IDMEPRTVEI NRELSDALGI SIAGGRGSPL
1710 1720 1730 1740 1750
GDIPIFIAMI QASGVAARTQ KLKVGDRIVS INGQPLDGLS HADVVNLLKN
1760 1770 1780 1790 1800
AFGRIILQVV ADTNISAIAA QLENMSTGYH LGSPTAEHHR EDTEEPLQMT

AD
Length:1,802
Mass (Da):196,595
Last modified:March 28, 2018 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB4F9B92A59D565C5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2K6B0I5A0A2K6B0I5_MACNE
PATJ crumbs cell polarity complex c...
PATJ
1,192Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2K6B0F4A0A2K6B0F4_MACNE
PATJ crumbs cell polarity complex c...
PATJ
452Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2K6B0H5A0A2K6B0H5_MACNE
PATJ crumbs cell polarity complex c...
PATJ
589Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2K6B0H7A0A2K6B0H7_MACNE
PATJ crumbs cell polarity complex c...
PATJ
1,159Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A2K6B0F9A0A2K6B0F9_MACNE
PATJ crumbs cell polarity complex c...
PATJ
1,179Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

NCBI Reference Sequences

More...
RefSeqi
XP_011762734.1, XM_011764432.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMNET00000024360; ENSMNEP00000004882; ENSMNEG00000022006

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
105495168

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

RefSeqiXP_011762734.1, XM_011764432.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

EnsembliENSMNET00000024360; ENSMNEP00000004882; ENSMNEG00000022006
GeneIDi105495168

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
10207

Phylogenomic databases

GeneTreeiENSGT00940000155136
OMAiELLEXNE
OrthoDBi1419918at2759

Family and domain databases

InterProiView protein in InterPro
IPR015132 L27_2
IPR004172 L27_dom
IPR036892 L27_dom_sf
IPR001478 PDZ
IPR041489 PDZ_6
IPR036034 PDZ_sf
PfamiView protein in Pfam
PF09045 L27_2, 1 hit
PF00595 PDZ, 9 hits
PF17820 PDZ_6, 1 hit
SMARTiView protein in SMART
SM00569 L27, 1 hit
SM00228 PDZ, 10 hits
SUPFAMiSSF101288 SSF101288, 1 hit
SSF50156 SSF50156, 10 hits
PROSITEiView protein in PROSITE
PS51022 L27, 1 hit
PS50106 PDZ, 10 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiA0A2K6B0E9_MACNE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: A0A2K6B0E9
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: March 28, 2018
Last sequence update: March 28, 2018
Last modified: December 11, 2019
This is version 14 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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